Antibiotics P1

Which statement best defines a health care–associated infection (HAI)?

• Infection present at admission

• Infection occurring >48 hours after admission

• Infection acquired in the community

• Infection present with colonization only

Empiric antibiotic therapy refers to:

• Using narrowest drug after cultures return

• Immediate broad coverage based on likely pathogens

• Withholding therapy until sensitivities result

• Prophylaxis before clean procedures

Which pair shares the same mechanism of action?

• Macrolides and tetracyclines

• Penicillins and cephalosporins

• Quinolones and aminoglycosides

• Sulfonamides and monobactams

A patient reports throat swelling with penicillin. Which antibiotic is most concerning?

• Azithromycin

• Cefazolin

• Doxycycline

• Ciprofloxacin

Sulfonamides are commonly used for which infection due to high renal concentrations?

• Otitis media

• Urinary tract infection

• Cellulitis

• Pharyngitis

Which macrolide effect can be therapeutically useful in gastroparesis?

• QT shortening

• GI motility stimulation

• Calcium channel blockade

• Beta-lactamase inhibition

Which carbapenem-related precaution is priority?

• Seizure risk

• Red man syndrome

• Ototoxicity

• Photosensitivity

Aztreonam is most active against:

• Anaerobes

• Gram-positive cocci

• Aerobic gram-negative rods

• Fungi

Which organism is typically treated with vancomycin as drug of choice?

• MRSA

• ESBL E. coli

• CRE Klebsiella

• Pseudomonas

Which lab/monitoring is essential with daptomycin therapy?

• Lipase weekly

• CPK levels

• TSH monthly

• Amylase only