Cori Cycle Lactate Recycling

The video tutorial discusses two metabolic pathways involving skeletal muscles: the Cori cycle and the glucose-alanine cycle. It focuses on the role of lactate dehydrogenase in converting pyruvate to lactate under anaerobic conditions and vice versa under aerobic conditions. The Cori cycle is explained in detail, highlighting how lactate produced in muscles is transported to the liver, converted back to glucose, and then returned to muscles as a fuel source. This cycle is crucial during high-intensity exercise when oxygen is limited.

What are the two cycles discussed that are commonly confused in exercise physiology?

• Electron transport chain and glycolysis

• Krebs cycle and urea cycle

• Cori cycle and glucose-alanine cycle

• Beta-oxidation and gluconeogenesis

Which enzyme is crucial for the conversion of pyruvate to lactate under anaerobic conditions?

• Aldolase

• Lactate dehydrogenase

• Pyruvate kinase

• Hexokinase

Under what conditions does pyruvate convert to lactate?

• Aerobic conditions

• Low ATP levels

• High glucose levels

• Anaerobic conditions

In the Cori cycle, what happens to lactate produced in the muscles?

• It is stored in the muscles

• It is converted to glucose in the liver

• It is used directly for energy

• It is excreted from the body

What process converts pyruvate back to glucose in the liver during the Cori cycle?

• Beta-oxidation

• Gluconeogenesis

• Transamination

• Glycolysis

What is the primary fuel source for the liver during the Cori cycle?

• Glucose

• Lactate

• Lipids

• Proteins

What is the main significance of the Cori cycle?

• It increases the oxygen supply to muscles

• It helps in the storage of glucose in muscles

• It enhances protein synthesis in muscles

• It converts muscle waste into a usable fuel source