Rheumatoid Arthritis Treatment and Effects

Rheumatoid arthritis (RA) is an autoimmune disease causing joint inflammation and damage. It affects 1-1.5% of North Americans, predominantly women. RA incurs significant economic costs. Treatments include NSAIDs and DMARDs, which reduce symptoms and prevent joint damage. DMARDs are categorized into small molecule and biologic types, each with distinct production, cost, and administration challenges. Biologic DMARDs are expensive and used when other treatments fail. Both types can cause side effects and increase infection risk. DMARDs also treat other immune disorders.

What is the primary area affected by the chronic inflammation caused by Rheumatoid Arthritis?

• The bones

• The cartilage

• The synovium or lining of the joints

• The muscles

Which demographic is more likely to be affected by Rheumatoid Arthritis?

• Children

• Women

• Elderly

• Men

What is the primary limitation of NSAIDs in the treatment of RA?

• They cause severe side effects

• They do not slow disease progression

• They do not relieve pain

• They are too expensive

What is the main function of DMARDs in RA treatment?

• To reduce swelling

• To relieve pain

• To increase joint flexibility

• To limit underlying inflammation

What distinguishes biologic DMARDs from small molecule DMARDs?

• They are cheaper to produce

• They are taken orally

• They are smaller in size

• They are antibodies

How are biologic DMARDs typically administered?

• By injection

• Through inhalation

• Orally

• Topically

Why are biologic DMARDs more expensive than small molecule DMARDs?

• They are mass-produced

• They are chemically synthesized

• They have fewer side effects

• They require complex biological processes

What is a common side effect of small molecule DMARDs?

• Range of side effects

• Improved vision

• Hair loss

• Increased appetite

What is a potential risk associated with the immunosuppressive nature of DMARDs?

• Weight gain

• Improved immune function

• Opportunistic infections

• Increased energy levels

Besides RA, which condition can DMARDs also treat due to their immunosuppressive effects?

• Hypertension

• Asthma

• Plaque psoriasis

• Diabetes