Biosignaling - Receptor Tyrosine Kinases & Insulin

The video explains the receptor tyrosine kinase (RTK) pathway, focusing on insulin signaling. It describes how insulin binds to RTK, causing dimerization and activation through auto-phosphorylation. The pathway involves a series of proteins, including IRS-1, GRB2, SOS, and RAF1, leading to gene transcription. The video also discusses the role of RTKs in growth factor signaling and the potential for mutations in this pathway to cause cancer.

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