Cushings

What is Cushing's characterized by?

• Too little cortisol in the body

• Too much cortisol in the body

• Too little ACTH in the body

• Too much CRH in the body

Which sequence correctly describes the normal regulation of cortisol production?

• Hypothalamus secretes ACTH, which stimulates the anterior pituitary to secrete CRH, leading to cortisol production.

• Anterior pituitary secretes CRH, which stimulates the hypothalamus to secrete ACTH, leading to cortisol production.

• Hypothalamus secretes CRH, which stimulates the anterior pituitary to secrete ACTH, leading to cortisol production by the adrenal gland.

• Adrenal gland secretes cortisol, which stimulates the hypothalamus to secrete CRH, leading to ACTH production.

What is the most common cause of Cushing's Disease?

• An adrenal gland tumor

• A hypothalamic lesion

• A pituitary adenoma

• Excessive external cortisol intake

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How do ACTH levels differ between Cushing's Disease and Cushing's Syndrome?

• Cushing's Disease has high ACTH, while Cushing's Syndrome has low ACTH.

• Cushing's Disease has low ACTH, while Cushing's Syndrome has high ACTH.

• Both Cushing's Disease and Cushing's Syndrome are characterized by high ACTH levels.

• Both Cushing's Disease and Cushing's Syndrome are characterized by low ACTH levels.

What effect does long-term exogenous cortisol (e.g., prednisone) administration have on the adrenal glands?

• The adrenal glands increase in size due to overstimulation.

• The adrenal glands atrophy due to a lack of ACTH stimulation.

• Only one adrenal gland atrophies, while the other remains normal.

• The adrenal glands become hyperactive and produce excessive cortisol.