WorksheetsBiomedical Midterm
Total questions: 48
Worksheet time: 24mins
The use of mice in biomedical research most frequently occurs at which level
Basic
Applied
Clinical
Descriptive epidemiology studies identify
Direct cause and effect
Correlations
Selection bias
Which group is often given a placebo or inactive substance when a new medication is tested in biomedical research
Experimental
Control
Homogeneous
Which type of research involves human subjects and is conducted after other forms of research have already taken place
Basic Research
Applied research
Clinical Research
Which term best describes the study of disease incidence and its distribution in a population
Comparisons
Descriptive
Epidemiology
Stan is working with a type of research study with limitations. The study cannot respond to other functions within a living organism or whole body system. What type is this?
Basic
In vitro
Phase 1
What stage of clinical trials involves extensive testing, using around 1000- 3000 subjects, overall purpose of determining a drug's efficacy and adverse reactions?
Phase 1
Phase 2
Phase 3
Which type of research method may be conducted on either animals, humans, computer models, or tissue cultures?
Clinical Research
In vitro Research
Applied Research
Julio is a researcher and has been assigned to collect data on the Zika virus. What level of research is he working on if his findings will be used to develop a vaccine or new treatment?
Basic
Applied
Clinical
Which type of research is directed toward specific objectives and is conducted using animals and other non animal models such as computers and tissue cultures?
Basic research
Applied Research
Descriptive Research
Chemical, mechanical, and computer simulations are effective research methods but cannot..
Replace building blocks
Replace laboratory testing on animals
Reduce the number of scientists needed
Scientists are currently conducting studies in vitro. Where are these studies most likely taking placed?
In a petri dish or test tube
In a living organism
in an animal cage
During biomedical research using animals, a control group was given a placebo. This group will most likely have what type of response?
A positive response
A negative response
No response
During which phase of clinical trials is the safety and effectiveness of a medication tested on the greatest number and variety of participants?
Phase 1
Phase 2
Phase 3
A major disadvantage of epidemiological studies is that?
They identify patterns in diseases
Ethical Issues may limit their usefulness
Considerable human exposure can take place before a toxic effect is detectable
Epidemiology studies may be divided up into three general types..
experimental,descriptive, and observational
experimental, comparison, and case controlled
observational, retrospective and experimental
An experimental medication is being tested on research mice. To obtain the most accurate results, the test should include an experimental group and a/an?
Epidemic group
Phase 1 group
Control group
Which agency is in charge of enforcing laws that regulate the use of animals in a research testing facility?
AWA
USDA
PETA
Animal research is only valid if the animals are?
over six months old
captured from the wild
not stressed out and are healthy
Which animal rights group stages controversial public demonstrations with activists dressed in attention-getting suits?
AHA
NIH
PETA
The agency that requires all prescriptions and over the counter drugs to be tested on animals before being tested on humans is the?
EPA
FDA
OSHA
The law or act that requires the humane and responsible treatment of animals that are used in biomedical research is the?
Animal Rights Act
Animal Testing Law
Animal Welfare Act
Human intolerance and discrimination of animals is known as?
Fanaticism
Socialism
Speciesism
Which animal, most often used in medical research, has a short life span, breeds easily, and is biologically similar to humans?
Cats
Dogs
Mice
The Animal Welfare Act was originally written to protect the use of?
All animals
All animals except birds, rats, and mice
Dogs and Cats
Scientists will have the opportunity to analyze their research over longer periods of time if animals have a longer:
Tolerance to trial medications
Life span
Coat of hair
The FBI has described the tactics of the Animal Liberation Front (ALF) as:
Domestic Terrorism
Supporting animal research
Non animal activism
The Animal Welfare Act states that the use of animals must be reviewed and approved by which organization?
FDA
PETA
IACUC
The main difference between animal rights and animal welfare is that people who support animal rights believe:
That animals do not have any rights
That humans do not have any rights
That humans should not interfere with the lives of animals
The Animal Welfare Act (AWA) applies to all:
Animal rights
Public and private research facilities
Zoos and Parks
What organization conducts unannounced inspections of animal research facilities?
CDC
FDA
USDA
Research experiments that use animals as models should be set up using the three R's, which are?
Restrict, reduce and reconfigure the use of animals
Reconstruct, recycle, and reconfigure the use of animals
Replace, reduce, and refine the use of animals
Which statement best describes the usefulness of animals in biomedical research?
They are similar to humans in their reactions and responses because they have similar biological structures
They provide a less complex system than in vitro studies
They are limited ethical concerns when using animals in research
In order for scientific findings to be valid and useful, research animals must be?
Housed in individual cages
Healthy and protected from undue stress
Allowed to roam freely within the facility
A xenograft is used in a heart transplant. Where did this tissue come from?
The recipient's body
An identical twin
A different species
What medical device made the external cardiac pump obsolete?
Pace maker
Heart-lung machine
Artificial heart
In regenerative medicine, once the bio material matrix is developed, the scaffolds must be able to :
Leave
Be made smaller
Dissolve
The chromosome pairing XX in a human represents?
A female
A male
Identical twins
Implanting a gene from one organism into an embryo will create a ?
New species
Transgenic animal
Mutant
Replace, reduce, and refine are alternative scientific methods researchers use to?
Examine cellular tissues
Maintain all lab equipment
Design experiments that do not use animals
Regenerative medicine relies heavily on the use of?
Organs harvested from animals
Clones
Stem cells
When a scientist charts the position of known genes and other markers relative to each other, this process is called?
Genome tracing
Genetic engineering
Genetic mapping
Somatic stem cells are undifferentiated cells that are also called?
Embryonic stem cells
Adult stem cells
Zygote stem cells
When creating a cloned mammal, what structures contains the genetic information the scientist intends to clone?
Blastocyst
Surrogate mother
Somatic cell
Examining properties that can be described as one-billionth are?
Genoparticles
Megaparticles
Nanoparticles
Adult stem cells are to be harvested and transplanted into a patient. Where would these cells most likely be found?
In an embryo
In muscle tissue
In human bone marrow
Pluripotent stem cells (iPS cells) are reprogrammed adult cells produce in a lab to take on characteristics of which type of stem cell?
Somatic stem cell
Tissue-specific stem cells
Embryonic stem cells
Chemical properties refer to how the material will?
Be calculated
Interact with other materials
Be pharmed
