WorksheetsDNA Replication and Protein Synthesis
Total questions: 50
Worksheet time: 25mins
In his experiment with streptococcus pneumoniae, Griffith found that
The DNA of the heat killed S bacteria entered some of the R bacteria when mixed.
The S bacteria were transformed
The capsule did not protect the bacterium
Mice injected with the R bacteria always died.
Hershey and Chase used bacteriophage with radioactive labels to determine genetic material is made up of
Proteins
RNA
DNA
Bacteriophage
In the Hershey and Chase experiment they used radioactive phosphorus to trace the _?_ and radioactive sulfur to trace the _?_.
DNA, Protein
Protein, DNA
Bacteriophage, e-coli
E.coli, Bacteriophage
A microorganism's ability to cause disease is known as its
Vaccine
Adaptability
Transformation
Virulence
What is the name of the process that was involved in changing Griffith’s R bacteria into S bacteria?
DNA replication
Transformation
Crossing-over
Polymerization
A base that forms bonds with Cytosine is
Guanine
Adenine
Thymine
Uracil
Two strands of nucleotides winding around each other like a twisted ladder is known as a
Double helix
Helicses
Pyrimidine
Deoxyribose
DNA consists of a 5 carbon sugar called
Ribose
Deoxyribose
Cytosine
Uracil
What two alternating molecules make up the backbone of the DNA strand?
Purine & Pyrimidines
Adenine & Thymine
Sugar & Phosphate
Cytosine & Guanine
A DNA nucleotide does not include a
5 carbon sugar
Double helix
Phosphate group
Nitrogen base
Choose the complementary strand to the DNA strand below:
C G A T G G A T T C
CGA TGG ATT C
TAG CAA GCC T
GCT ACC TAA G
ATC GTT CGG A
When DNA makes an extra copy of itself, this is known as
DNA replication
Transformation
Translation
DNA repeat
Proteins are made up of _?_.
Blocks
Amino Acids
Pepcids Chains
Ribosomes
Each set of three bases representing an amino acid on a mRNA molecule known as_?_.
tRNA
nucleotide
ribosome
codon
Fill in the complementary sequence that RNA would code off of this DNA sequence
A T C G T T C A T A A G C A T
TAG CAA GTA TTCGTA
UAG CAA GUA UUCGUA
TUG CUU GTU TTCGTU
UAG UAA GTA TTUGTA
RNA does not contain the nitrogen base Thymine like DNA. In place of thymine, RNA contains __?__?
Adenine
Cytosine
Uracil
Guanine
Which of the following is not a difference between DNA and RNA?
RNA has Uracil while DNA has Thymine
RNA is single stranded and DNA is double stranded
RNA does not have the phosphate backbone and DNA does
RNA has the sugar ribose, while DNA has the sugar deoxyribose
During transcription, the enzyme helicase is responsible for…
Adding nucleotides to the exposed complementary nitrogen bases
Breaking the hydrogen bonds that hold the two strands together
Binds the DNA strands back together when the replication is complete
Transports the needed nitrogen bases to the RNA
During transcription, the enzyme polymerase is responsible for…
Adding RNA nucleotides to the exposed DNA bases
Breaking the hydrogen bonds that hold the two strands together
Binds the DNA strands back together when the replication is complete
Transports the needed nitrogen bases to the RNA
The portion of DNA where the double helix separates during transcription is known as _?_.
Replication spoon
Replication fork
Deoxyribose
Hydrogen bond
which of the following mRNA sequences codes for Valine (Val), Glutamic acid (Glu), and serine (Ser)
UGG-AGG-CUA
GUA-GGG-AGC
GUC-GAA-ACU
GUG-GAG-AGC
The mRNA sequence ACU codes for the amino acid Thr. A mutation occurs, and the resulting mRNA sequence is AUU. What amino acid will replace Thr?
Val
Met
lle
Ala
Persons A and B have similar mRNA sequences with the exception of 1 nucleotide.
Person A: AUGGUUACUAAGGGCUGA
Person B: AUGGUUACUGAGGGCUGA
Use the genetic code chart to determine how this difference affects the sequence of amino acids in the resulting protein.
Lys in Person A is replaced with Glu in Person B.
Phe in Person A is replaced with Leu in Person B.
Persons A and B have identical amino acid sequences.
A stop codon is generated in Person B and not in Person A.
1 and 2 only
1 and 3 only
2 and 3 only
1, 2, and 3
A, G, T, and C occur in equal percentages
A and G occur in equal percentages, and T and C occur in equal percentages
A and T occur in equal percentages, and G and C occur in equal percentages
A and C occur in equal percentages, and T and G occur in equal percentages
Figure 12–2 shows the structure of
DNA molecule.
amino acid.
RNA molecule.
protein
Which of the following is a nucleotide found in DNA?
adenine + phosphate group + thymine
cytosine + phosphate group + guanine
deoxyribose + phosphate group + polymerase
deoxyribose + phosphate group + cytosine
The table in Figure 12–3 shows the results of measuring the percentages of the four bases in the DNA of several different organisms. Some of the values are missing from the table. Based on Chargaff’s rule, the percentages of guanine bases in chicken DNA should be around
28.8%
19.9%
21.5%
13.4%
Which scientist(s) figured out that the shape of a DNA molecule is a double helix?
Hershey and Chase
Griffith
Watson and Crick
Franklin
What would happen to the percentage of G in Figure 12–4 if the percentage of A rose to 25%?
G would drop to 19%
G would drop to 25%
G would rise to 29%
G would rise to 32%
DNA replication results in two DNA molecules,
each with two new strands. .
one with two new strands and the other with two original strands.
each with one new strand and one original strand.
each with two original strands.
During DNA replication, a DNA strand that has the bases CTAGGT produces a strand with the bases
TCGAAC.
GATCCA.
AGCTTG.
GAUCCA
What enzyme works to add DNA to ends of chromosomes in rapidly dividing cells such as those found in an embryo, to prevent genes from being lost during replication?
DNA polymerase
histones
telomerase
chromatin
In Figure 12–5, what nucleotide is going to be added at point 1, opposite from thymine?
adenine
thymine
cytosine
guanine
In eukaryotes (Animal cell), DNA
is located in the nucleus.
floats freely in the cytoplasm.
is located in the ribosomes.
is circular.
In both prokaryotes and eukaryotes, how many copies of the chromosome are left after replication?
1
2
3
4
In both prokaryotes and eukaryotes, DNA replication happens
before cell division.
in the nucleus.
only to telomeres.
around the histones.
RNA contains the sugar
ribose.
deoxyribose.
glucose.
lactose
Which of the following are found in both DNA and RNA?
ribose, phosphate groups, and adenine
deoxyribose, phosphate groups, and guanine
phosphate groups, guanine, and cytosine
phosphate groups, guanine, and thymine
Which nucleotide in Figure 13–1 indicates the nucleic acid above is RNA?
uracil
guanine
cytosine
adenine
Which of the following is true of transcription?
In eukaryotes, transcription takes place in the cytoplasm and requires many enzymes.
RNA polymerase recognizes and binds to specific regions of the DNA called introns.
RNA editing removes the exons from pre-mRNA, leaving only the introns in the final molecule.
RNA polymerase can make many molecules of RNA from a single DNA sequence.
Which molecules are involved in protein synthesis?
transfer RNA, introns, and mutagens
t messenger RNA, introns, and ribosomal RNA
ribosomal RNA, transfer RNA, and mutagens
messenger RNA, ribosomal RNA, and transfer RNA
During eukaryotic transcription, an RNA molecule is formed that is
complementary to both strands of DNA.
identical to an entire single strand of DNA. .
double-stranded and inside the nucleus.
complementary to part of one strand of DNA .
How many nucleotides are needed to specify three amino acids?
3
6
9
12
When Griffith mixed heat-killed, harmful bacteria with live, harmless bacteria and injected the mixture into mice, the mice died.
True
False
Bacteriophages inject protein into bacteria, altering the bacteria’s genetic information.
true
false
Watson and Crick discovered that covalent bonds hold base pairs together at the center of a strand of DNA. _________________________
true
false
In Figure 12–4, the percentages of all four columns should add up to 90.
True
False
In Figure 12–5, what nucleotide is going to be added at point 1, opposite from thymine?
adenine
thymine
cytosine
guanine
In which step of the cell cycle does DNA replication occur?
G1
M
S
G2
