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DNA Replication and Protein Synthesis

Total questions: 50

Worksheet time: 25mins

Name
Class
Date
1.

In his experiment with streptococcus pneumoniae, Griffith found that

a)

The DNA of the heat killed S bacteria entered some of the R bacteria when mixed.

b)

The S bacteria were transformed

c)

The capsule did not protect the bacterium

d)

Mice injected with the R bacteria always died.

2.

Hershey and Chase used bacteriophage with radioactive labels to determine genetic material is made up of

a)

Proteins

b)

RNA

c)

DNA

d)

Bacteriophage

3.

In the Hershey and Chase experiment they used radioactive phosphorus to trace the _?_ and radioactive sulfur to trace the _?_.

a)

DNA, Protein

b)

Protein, DNA

c)

Bacteriophage, e-coli

d)

E.coli, Bacteriophage

4.

A microorganism's ability to cause disease is known as its

a)

Vaccine

b)

Adaptability

c)

Transformation

d)

Virulence

5.

What is the name of the process that was involved in changing Griffith’s R bacteria into S bacteria?

a)

DNA replication

b)

Transformation

c)

Crossing-over

d)

Polymerization

6.

A base that forms bonds with Cytosine is

a)

Guanine

b)

Adenine

c)

Thymine

d)

Uracil

7.

Two strands of nucleotides winding around each other like a twisted ladder is known as a

a)

Double helix

b)

Helicses

c)

Pyrimidine

d)

Deoxyribose

8.

DNA consists of a 5 carbon sugar called

a)

Ribose

b)

Deoxyribose

c)

Cytosine

d)

Uracil

9.

What two alternating molecules make up the backbone of the DNA strand?

a)

Purine & Pyrimidines

b)

Adenine & Thymine

c)

Sugar & Phosphate

d)

Cytosine & Guanine

10.

A DNA nucleotide does not include a

a)

5 carbon sugar

b)

Double helix

c)

Phosphate group

d)

Nitrogen base

11.

Choose the complementary strand to the DNA strand below:

C G A T G G A T T C

a)

CGA TGG ATT C

b)

TAG CAA GCC T

c)

GCT ACC TAA G

d)

ATC GTT CGG A

12.

When DNA makes an extra copy of itself, this is known as

a)

DNA replication

b)

Transformation

c)

Translation

d)

DNA repeat

13.

Proteins are made up of _?_.

a)

Blocks

b)

Amino Acids

c)

Pepcids Chains

d)

Ribosomes

14.

Each set of three bases representing an amino acid on a mRNA molecule known as_?_.

a)

tRNA

b)

nucleotide

c)

ribosome

d)

codon

15.

Fill in the complementary sequence that RNA would code off of this DNA sequence


A T C G T T C A T A A G C A T

a)

TAG CAA GTA TTCGTA

b)

UAG CAA GUA UUCGUA

c)

TUG CUU GTU TTCGTU

d)

UAG UAA GTA TTUGTA

16.

RNA does not contain the nitrogen base Thymine like DNA. In place of thymine, RNA contains __?__?

a)

Adenine

b)

Cytosine

c)

Uracil

d)

Guanine

17.

Which of the following is not a difference between DNA and RNA?

a)

RNA has Uracil while DNA has Thymine

b)

RNA is single stranded and DNA is double stranded

c)

RNA does not have the phosphate backbone and DNA does

d)

RNA has the sugar ribose, while DNA has the sugar deoxyribose

18.

During transcription, the enzyme helicase is responsible for…

a)

Adding nucleotides to the exposed complementary nitrogen bases

b)

Breaking the hydrogen bonds that hold the two strands together

c)

Binds the DNA strands back together when the replication is complete

d)

Transports the needed nitrogen bases to the RNA

19.

During transcription, the enzyme polymerase is responsible for…

a)

Adding RNA nucleotides to the exposed DNA bases

b)

Breaking the hydrogen bonds that hold the two strands together

c)

Binds the DNA strands back together when the replication is complete

d)

Transports the needed nitrogen bases to the RNA

20.

The portion of DNA where the double helix separates during transcription is known as _?_.

a)

Replication spoon

b)

Replication fork

c)

Deoxyribose

d)

Hydrogen bond

21.

which of the following mRNA sequences codes for Valine (Val), Glutamic acid (Glu), and serine (Ser)

a)

UGG-AGG-CUA

b)

GUA-GGG-AGC

c)

GUC-GAA-ACU

d)

GUG-GAG-AGC

22.

The mRNA sequence ACU codes for the amino acid Thr. A mutation occurs, and the resulting mRNA sequence is AUU. What amino acid will replace Thr?

a)

Val

b)

Met

c)

lle

d)

Ala

23.

Persons A and B have similar mRNA sequences with the exception of 1 nucleotide.


Person A: AUGGUUACUAAGGGCUGA

Person B: AUGGUUACUGAGGGCUGA


Use the genetic code chart to determine how this difference affects the sequence of amino acids in the resulting protein.

a)

Lys in Person A is replaced with Glu in Person B.

b)

Phe in Person A is replaced with Leu in Person B.

c)

Persons A and B have identical amino acid sequences.

d)

A stop codon is generated in Person B and not in Person A.

24.
a)

1 and 2 only

b)

1 and 3 only

c)

2 and 3 only

d)

1, 2, and 3

25.
a)

A, G, T, and C occur in equal percentages

b)

A and G occur in equal percentages, and T and C occur in equal percentages

c)

A and T occur in equal percentages, and G and C occur in equal percentages

d)

A and C occur in equal percentages, and T and G occur in equal percentages

26.

Figure 12–2 shows the structure of

a)

DNA molecule.

b)

amino acid.

c)

RNA molecule.

d)

protein

27.

Which of the following is a nucleotide found in DNA?

a)

adenine + phosphate group + thymine

b)

cytosine + phosphate group + guanine

c)

deoxyribose + phosphate group + polymerase

d)

deoxyribose + phosphate group + cytosine

28.

The table in Figure 12–3 shows the results of measuring the percentages of the four bases in the DNA of several different organisms. Some of the values are missing from the table. Based on Chargaff’s rule, the percentages of guanine bases in chicken DNA should be around

a)

28.8%

b)

19.9%

c)

21.5%

d)

13.4%

29.

Which scientist(s) figured out that the shape of a DNA molecule is a double helix?

a)

Hershey and Chase

b)

Griffith

c)

Watson and Crick

d)

Franklin

30.

What would happen to the percentage of G in Figure 12–4 if the percentage of A rose to 25%?

a)

G would drop to 19%

b)

G would drop to 25%

c)

G would rise to 29%

d)

G would rise to 32%

31.

DNA replication results in two DNA molecules,

a)

each with two new strands. .

b)

one with two new strands and the other with two original strands.

c)

each with one new strand and one original strand.

d)

each with two original strands.

32.

During DNA replication, a DNA strand that has the bases CTAGGT produces a strand with the bases

a)

TCGAAC.

b)

GATCCA.

c)

AGCTTG.

d)

GAUCCA

33.

What enzyme works to add DNA to ends of chromosomes in rapidly dividing cells such as those found in an embryo, to prevent genes from being lost during replication?

a)

DNA polymerase

b)

histones

c)

telomerase

d)

chromatin

34.

In Figure 12–5, what nucleotide is going to be added at point 1, opposite from thymine?

a)

adenine

b)

thymine

c)

cytosine

d)

guanine

35.

In eukaryotes (Animal cell), DNA

a)

is located in the nucleus.

b)

floats freely in the cytoplasm.

c)

is located in the ribosomes.

d)

is circular.

36.

In both prokaryotes and eukaryotes, how many copies of the chromosome are left after replication?

a)

1

b)

2

c)

3

d)

4

37.

In both prokaryotes and eukaryotes, DNA replication happens

a)

before cell division.

b)

in the nucleus.

c)

only to telomeres.

d)

around the histones.

38.

RNA contains the sugar

a)

ribose.

b)

deoxyribose.

c)

glucose.

d)

lactose

39.

Which of the following are found in both DNA and RNA?

a)

ribose, phosphate groups, and adenine

b)

deoxyribose, phosphate groups, and guanine

c)

phosphate groups, guanine, and cytosine

d)

phosphate groups, guanine, and thymine

40.

Which nucleotide in Figure 13–1 indicates the nucleic acid above is RNA?

a)

uracil

b)

guanine

c)

cytosine

d)

adenine

41.

Which of the following is true of transcription?

a)

In eukaryotes, transcription takes place in the cytoplasm and requires many enzymes.

b)

RNA polymerase recognizes and binds to specific regions of the DNA called introns.

c)

RNA editing removes the exons from pre-mRNA, leaving only the introns in the final molecule.

d)

RNA polymerase can make many molecules of RNA from a single DNA sequence.

42.

Which molecules are involved in protein synthesis?

a)

transfer RNA, introns, and mutagens

b)

t messenger RNA, introns, and ribosomal RNA

c)

ribosomal RNA, transfer RNA, and mutagens

d)

messenger RNA, ribosomal RNA, and transfer RNA

43.

During eukaryotic transcription, an RNA molecule is formed that is

a)

complementary to both strands of DNA.

b)

identical to an entire single strand of DNA. .

c)

double-stranded and inside the nucleus.

d)

complementary to part of one strand of DNA .

44.

How many nucleotides are needed to specify three amino acids?

a)

3

b)

6

c)

9

d)

12

45.

When Griffith mixed heat-killed, harmful bacteria with live, harmless bacteria and injected the mixture into mice, the mice died.

a)

True

b)

False

46.

Bacteriophages inject protein into bacteria, altering the bacteria’s genetic information.

a)

true

b)

false

47.

Watson and Crick discovered that covalent bonds hold base pairs together at the center of a strand of DNA. _________________________

a)

true

b)

false

48.

In Figure 12–4, the percentages of all four columns should add up to 90.

a)

True

b)

False

49.

In Figure 12–5, what nucleotide is going to be added at point 1, opposite from thymine?

a)

adenine

b)

thymine

c)

cytosine

d)

guanine

50.

In which step of the cell cycle does DNA replication occur?

a)

G1

b)

M

c)

S

d)

G2