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Protein Synthesis and Mutation

Total questions: 34

Worksheet time: 38mins

Name
Class
Date
1.
Original: ATC CAT
Mutation: ATC GCAT
What mutation occurred?
a)
deletion
b)
insertion
c)
silent
d)
transverse
2.

Where do mutations occur?

a)

DNA and RNA

b)

DNA

c)

RNA

d)

mRNA and tRNA

3.
Translation takes place in the 
a)
ribosome
b)
chloroplast
c)
nucleus
d)
mitochondria
4.
Where does transcription take place?
a)
nucleus
b)
cytoplasm
c)
ribosome
5.
How many amino acids are coded for by this sequence of nucleotides:
ATG GGA ACT CCA
a)
4
b)
2
c)
6
d)
12
6.
What is occurring in this picture?
a)
Translation
b)
Replication
c)
Translocation
d)
Transcription
7.
This diagram can be used to -
a)
translate codon into protein
b)
transcribe DNA into RNA
c)
duplicate DNA
d)
cell division
8.
What mutation has occurred here? 
T-G-A-C-C-A
T-G-A-G-C-A
a)
Substitution
b)
Deletion
c)
Insertion
d)
Frameshift 
9.
Any change in the sequence of DNA is...
a)
transgenic shift
b)
Single Genotype
c)
Monohybrid Trait
d)
Mutation
10.
ATTTGAGCC- Original
ATTGAGCC - Mutated
The example above is an example of a 
a)
Insertion- Frameshift
b)
Deletion- Substitution
c)
Deletion -Frameshift
d)
All of the above
11.
Which phrase best describes translation?
a)
converts mRNA into a protein 
b)
catalyzes bonds between amino acids
c)
produces RNA from DNA molecules
d)
recycles tRNA molecules for reuse
12.
Which RNA bases would pair with TACGAA in transcription? 
a)
AUGCUU
b)
ATGCTT
c)
GCATCC
d)
GCAUCC
13.

DNA holds the code for

a)

lipids

b)

carbohydrates

c)

polypeptides

d)

sugar

14.
Choose the nucleotide sequence of the RNA strand that would be complementary to the following strand: 
GTAGTCA
a)
UATUAGA
b)
ACGACTG
c)
CAUCAGU
d)
CATCAGT
15.
Which of these nitrogenous bases is NOT in RNA?
a)
Uracil
b)
Thymine
c)
Cytosine
d)
Guanine
16.
The mRNA leaves the ________ to find the ribosome to make proteins.
a)
cell
b)
nucleotide
c)
nucleus
17.
What amino acid is represented by the codon UUA?
a)
Phenylalanine
b)
Tyrosine
c)
Leucine
d)
Stop codon
18.

Identify the ADDITION mutation form the following:

ATG CCA AAT

a)

ATG TCA AAT

b)

ATG CCT AAA T

c)

not a choice

d)

not a choice

19.

Identify the DELETION mutation form the following:

ATG CCA AAT

a)

ATG TCA AAT

b)

not a choice

c)

ATC CA AT

d)

not a choice

20.

Identify the SUBSTITUTION mutation form the following:

ATG CCA AAT

a)

ATG TCA AAT

b)

not a choice

c)

ATC CA AT

d)

not a choice

21.
What process is going on in this photo? 
a)
Transcription 
b)
Translation 
c)
Replication 
d)
All the above 
22.
Which component of DNA determines the traits of an organism? 
a)
Nitrogen Bases
b)
Sugar-Phosphate Backbone
c)
Hydrogen bonds
23.
Does the order of amino acids in a protein matter?
a)
YES!
b)
NO!
24.
What is the correct amino acid sequence for the mRNA code AUGCCAGUAUGA
a)
Met-Pro-Ala-Val
b)
Met-Pro-Val
c)
Tyr-Gly-His
d)
Tyr-Gly-Arg-His
25.

Which group contains the three main types of RNA that are always used in protein synthesis?

a)

mRNA, miRNA, and rRNA

b)

mRNA, miRNA, and tRNA

c)

mRNA, rRNA, and tRNA

d)

mRNA, tRNA, and RNAi

26.
Which of the following would result in a frameshift mutation?
a)
Insertions only
b)
Substitution only
c)
Deletion only
d)
Insertions and Deletions
27.
Are all mutations bad?
a)
Yes
b)
No
c)
Maybe?
28.
Why are insertion and deletion mutations so harmful?
a)
They change all of the codons from the mutation on down the line, which changes the amino acid sequence
b)
They insert things that an organism doesn't need.
c)
They often delete things that organisms need.
d)
Insertion and deletions are not any more harmful than substitution mutations.
29.
A mutation that does NOT change the protein that is produced is called a 
a)
deletion mutation
b)
inversion mutation
c)
silent mutation
d)
transverse mutation
30.

A mutation in which only one nucleotide is altered is called a:

a)

Frameshift Mutation

b)

Deletion Mutation

c)

Point Mutation

d)

Insertion Mutation

31.

If a mutation codes for an early stop codon, it's called a:

a)

Point mutation

b)

Missense mutation

c)

Nonsense mutation

d)

Insertion mutation

32.

This figure is an example of a:

a)

Silent mutation

b)

Missense mutation

c)

Nonsense mutation

33.

A mutation that alters a single codon changes a single amino acid. This is called a:

a)

Missense

b)

Nonsense

c)

Silent

d)

Frameshift

34.

This figure is an example of:

a)

Missense

b)

Nonsense

c)

Silent

d)

Frameshift

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