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PHAR 114 MS Drugs SP19

Total questions: 30

Worksheet time: 22mins

Name
Class
Date
1.

Neuromuscular blocking agents are described as

a)

muscle relaxants

b)

paralytic agents

c)

anti-spasmotics

d)

DMARDs

2.

Which of the following is not considered an autoimmune disease?

a)

Multiple sclerosis (MS)

b)

Systemic lupus erythematosus (SLE)

c)

Osteoarthritis

d)

Myasthenia gravis

3.

Which of the following is used to treat muscle spasms in patients with MS?

a)

pancuronium

b)

meloxicam

c)

methotrexate

d)

tizanidine

4.

Which of the following does not require refrigeration?

a)

pancuronium (Pavalon)

b)

succinylcholine (Quelicin)

c)

vecuronium (Norcuron)

d)

cisatracurium (Nimbex)

5.

What class of drug with reverse nondepolarizing NMB drugs?

a)

benzodiazepine antagonist

b)

cholinesterase inhhibitors

c)

SSRIs

d)

anticholinergics

6.

Which of the following is not an indication for botulinum toxins?

a)

migraine headaches

b)

surgery

c)

cervical dystonia

d)

excessive sweating

7.

Which class of medication is prescribed commonly to suppress inflammation, reduce flare-ups, and treat pain in autoimmune disorders?

a)

Mineralocorticoids

b)

Muscle relaxants

c)

Bisphosphonates

d)

Glucocorticoids

8.

Which muscle relaxant drug is used to prevent/treat malignant hyperthermia?

a)

dantrolene (Dantrium)

b)

diazepam (Valium)

c)

tizanidine (Zanflex)

d)

carisprodol (Soma)

9.

Which muscle relaxant drug requires the warning: may change color of urine.

a)

cyclobenzaprine (Flexeril)

b)

methocarbamol (Robaxin)

c)

diazepam (Valium)

d)

orphenadrine (Norflex)

10.

Myasthenia Gravis is treated with which following classes of drugs?

a)

glucocorticoids

b)

cholinesterase inhhibitors

c)

DMARDs

d)

muscle relaxants

11.

Which symptom is characteristic of SLE (lupus)?

a)

muscle weakness

b)

osteoporosis

c)

pain in the big toe

d)

butterfly rash on the face

12.

All of the following are DMARDs except:

a)

interferon B-1a

b)

etanercept

c)

infliximab

d)

methotrexate

13.

USP <800> provides information on the handling of all of the following DMARDs except:

a)

cyclophosphamide (Cytoxan)

b)

methotrexate (Rhematrex)

c)

mitoxantrone (Navantrone)

d)

certolizumab (Cimzia)

14.

Use of glucocorticoids and immunsuppressant drugs increase the risk of ________________ in patients.

a)

anemia

b)

bruising

c)

infection

d)

osteoporosis

15.

Which statement is false regarding monoclonal antibodies?

a)

they have a drug stem of 'mab'

b)

they are stored in the refrigerator

c)

they are used for muscle spasms

d)

they are classified as immunomodulators

16.

hydroxychloroquine (Plaquenil) is used to treat RA and Lupus, and is classified as __________________ drug.

a)

interferon

b)

an antimalarial

c)

aminosalicylate

d)

TNF Inhibitor

17.

Which anti-gout medication inhibits production of uric acid and has a narrow therapeutic range?

a)

colchine

b)

probenacid

c)

febuxostat

d)

allopurinol

18.

Osteoporosis can be treated with all of the following except:

a)

bisphosphonates

b)

SERMS

c)

Calcitonin

d)

glucocorticoids

19.

Which of the following osteoporosis treatments is administered intranasally?

a)

denosumab (Prolia)

b)

calcitonin (Miacalcin)

c)

reloxifene (Evista)

d)

alendronate (Fosamax)

20.

All of the following are DMARDs except:

a)

monoclonal antibodies

b)

gold salts

c)

leukotriene inhibitors

d)

interferons

21.

Which agent is used to treat Multiple Sclerosis?

a)

fingolimod (Gilenya)

b)

methotrexate (Trexall)

c)

infliximab (Remicade)

d)

diazepam (Valium)

22.

Tumor necrosis factor-a inhibitors are _____________ engineered drugs that block the inflammatory process triggered by high concentrations of tumor necrosis factor.

a)

chemically

b)

biologically

c)

neurologically

d)

synthetically

23.

Select the false statement regarding the oral administration of the bisphosphonates.

a)

After taking the medication patients must stay in the upright position for 30 minutes.

b)

Oral absorption is very poor.

c)

Patients should take these drugs with a full glass of water.

d)

They are administered on an empty stomach, at least 30 minutes after the first meal of the day.

24.

Vitamin _____ is involved in the formation of osteoclasts.

a)

A

b)

B

c)

C

d)

D

e)

E

25.

For raloxifene (Evista) to work, what hormone must be present?

a)

testosterone

b)

minercordicoids

c)

vitamin D

d)

estrogen

26.

Which of the following is only administered once a year?

a)

alendronate (Fosamax)

b)

zoledronic acid (Reclast)

c)

ibandronate (Boniva)

d)

etidronate (Didronel)

27.

Drugs that decrease ACh release or deplete the neuron of ACh will also cause _____ of muscles.

a)

relaxation

b)

stiffening

c)

contraction

d)

tremor

28.

Which of the following drug classes inhibits osteoclasts from removing calcium from the bone tissue?

a)

corticosteroids

b)

insulin

c)

SERM

d)

bisphosphonates

29.

Drugs that inhibit uric acid synthesis are used to treat:

a)

MG

b)

Gout

c)

Osteoporosis

d)

MS

30.

Patients taking skeletal muscle relaxants should avoid using all of the following except:

a)

opiates

b)

alcohol-containing cough preprations

c)

CNS depressant medications

d)

NSAIDs