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DNA Test Review

Total questions: 70

Worksheet time: 46mins

Name
Class
Date
1.
What is the  name of this image
a)
Image 51
b)
Series 51
c)
Franklin's Photograph
d)
Photograph 51
2.
Who is responsible for producing this image?
a)
Francis Crick
b)
James Watson
c)
Rosalind Franklin
d)
Watson and Crick
3.

What does this image show?

a)

The structure of DNA

b)

The structure of a carbohydrate

c)

The structure of a protein

d)

The structure of a lipid

4.

Who was awarded the Nobel Prize for the discovery of DNA?

a)

Rosalind Franklin

b)

Francis Crick

c)

James Watson

d)

Maurice Wilkins

5.
How did Rosalind take pictures of the shape of DNA
a)
X-Ray diffraction
b)
X-Ray microscopy
c)
Scanning Electron Microscope
d)
Radioation diffraction
6.
What type of macromolecule is DNA?
a)
Protein
b)
Lipid
c)
Carbohydrate
d)
Nucleic Acid
7.
What is the monomer of nucleic acids?
a)
Amino acids
b)
Monosaccharides
c)
Nucleotide
d)
Fatty acids
8.
What are the 3 parts of a Nucleotide?
a)
5 Carbon sugar, Phosphate group, Nitrogen containing base
b)
Sugar and a fatty acid tail
c)
Chains of amino acids
d)
None of the above
9.
The overall shape of a DNA molecule is called...
a)
Single stranded
b)
Double Helix
c)
Globular shape
d)
Circular
10.
What does Chargraff's rule state?
a)
In a sample of DNA..A=T
G=C
b)
In a sample of DNA   A=G
T=C
c)
In a sample of DNA  A=U  C=T
d)
None of the above
11.
What type of chemical bond holds the "backbone" of a DNA molecule together?
a)
Ionic
b)
Hydrogen
c)
Covalent
d)
Hydrophobic
12.
What type of chemical bond holds the Nitrogen bases together?
a)
Covalent
b)
Hydrogen
c)
Ionic
d)
Hydrophobic
13.
What makes up the "rungs" of the ladder in a DNA molecule?
a)
Nitrogen bases 
b)
Phosphate group
c)
Deoxyribose
d)
Amino acids
14.
The sugar found in DNA is called..
a)
Fructose
b)
Glucose
c)
Ribose
d)
Deoxyribose
15.
What is pictured?
a)
Amino acid
b)
Nucleic acid
c)
Nucleotide
d)
DNA molecule
16.
Which enzyme has the job of unzipping the double helix?
a)
Helicase
b)
Polymerase
c)
Ligase
d)
Primerase
17.
Which enzyme fixes the Okazaki fragments in the lagging strand?
a)
Helicase
b)
Polymerase
c)
Ligase
d)
Primerase
18.
If a strand reads:
3' A A A T T T C 5'
The matching strand would read...
a)
5' T T T A A A G 3'
b)
3' T T T A A A G 5'
c)
5' A A A T T T C 3'
d)
3' U U U A A A G 5'
19.

What are the gaps between the newly synthesized DNA molecule on the lagging strand called?

a)

Okazaki fragments

b)

Polymer gaps

c)

Helicase fragments

d)

Acidic gaps

20.
This picture is illustrating the ____ nature of DNA.
a)
anti-parallel
b)
deoxyribosic
c)
helical
d)
radioactive
21.

This enzyme builds DNA.

a)

DNA Polymerase

b)

Heicase

c)

Ligase

d)

Primase

22.

This enzyme adds RNA primers needed to start the duplication of DNA.

a)

DNA Polymerase

b)

Heicase

c)

Ligase

d)

Primase

23.

The strand created by DNA polymerase following the helicase.

a)

Leading strand

b)

Lagging strand

c)

Okazaki fragments

24.

The strand created by several DNA polymerase enzymes moving in the opposite direction of helicase.

a)

Leading strand

b)

Lagging strand

c)

Okazaki fragments

25.

The fragments of new DNA found on the lagging strand are called ___ fragments.

a)

Primer

b)

STR

c)

Okazaki

d)

Watson and Crick

26.

What would the amino acid sequence be for TAGTGATTTAAT?

a)

met-asn-phe-his

b)

gly-arg-ser-pro

c)

ser-ala-glu-gly

d)

ile-thr-lys-leu

27.

What would the mRNA be from the template strand?

a)

AUCACUAAAUUA

b)

UACUAAUUUA

c)

TAATTTAGTGAT

d)

AATCGCGATTGCA

28.

Messenger RNA is formed in the process of

a)

translation

b)

mutation

c)

replication

d)

transcription

29.
This type of substitution codes for a stop codon
a)
Missense
b)
Nonsense
c)
Silent
d)
Deletion
30.
If you are missing or have an extra base  at the end of your mutated DNA . What type of mutation occurred?
a)
Substitution
b)
Frameshift
c)
Duplication 
d)
Insertion
31.
A type of substitution in which no  amino acids change is called 
a)
Missense
b)
Nonsense
c)
Silent
d)
Deletion
32.
Which of the following would result in a frameshift mutation?
a)
Insertions only
b)
Substitution only
c)
Deletion only
d)
Insertions and Deletions
33.
DNA molecule segment is : TTACGCAAG
The mutated DNA segment is TTCGCAAG. This is an example of ___ mutation.
a)
Substitution
b)
Deletion
c)
Insertion
d)
Inversion
34.
mRNA is read in chunks of three, called...
a)
quadralets
b)
anticodons
c)
codons
d)
capsids
35.
Normal-
GAG-CTC-GAC-AGA
Mutant
GAG CTC-CAC-AGA
a)
no mutation
b)
substitution
c)
insertion
d)
deletion
36.
What mutation has occurred here? 
T-G-A-C-C-A
T-G-A-G-C-A
a)
Substitution
b)
Deletion
c)
Insertion
d)
Frameshift 
37.
Original: ATC CAT
Mutation: ATC GCAT
What mutation occurred?
a)
deletion
b)
insertion
c)
silent
d)
transverse
38.
Original: A A U U G G C C
Mutated: A U U U G G C C
What kind of mutation occurred?
a)
Substitution
b)
Addition
c)
Deletion
d)
Frameshift
39.

A frameshift mutation can occur with either _________ or __________ mutations.

a)

Insertion, division

b)

Deletion, substitution

c)

Insertion, substitution

d)

Insertion, deletion

40.

Which type of mutation is MOST LIKELY to cause the greatest change to gene that codes for a protein?

a)

Frameshift

b)

Silent

c)

Point

41.

This molecule prevents a gene from being expressed in the lac operon.

a)

repressor

b)

RNA polymerase

c)

Ribosome

d)

Beta-galactosidase

e)

Permease

42.

In a lac operon, this enzyme will transcribe a gene into mRNA once the repressor is removed.

a)

repressor

b)

RNA polymerase

c)

Ribosome

d)

Beta-galactosidase

e)

Permease

43.

This must bind to the mRNA to translate it into a protein.

a)

repressor

b)

RNA polymerase

c)

Ribosome

d)

Beta-galactosidase

e)

Permease

44.

In a lac operon, this enzyme is produced which splits a lactose molecule into two simple sugars

a)

repressor

b)

RNA polymerase

c)

Ribosome

d)

Beta-galactosidase

e)

Permease

45.

In a lac operon, this enzyme speeds up the import of lactose into a bacterial cell.

a)

repressor

b)

RNA polymerase

c)

Ribosome

d)

Beta-galactosidase

e)

Permease

46.

In eukaryotes, genes that are expressed all the time because they are constantly being used is made by the process of ___.

a)

Constitutive transcription

b)

Regulated transcription

47.

In eukaryotes, genes that are expressed only when they are needed are made by the process of ___.

a)

Constitutive transcription

b)

Regulated transcription

48.

Proteins that regulate transcription in a eukaryotic cell.

a)

Transcription factors

b)

Signal molecules

c)

Phosphates

49.

This molecule starts regulated transcription in a eukaryotic cell.

a)

Transcription factor

b)

Signal molecule

c)

Phosphate

50.

Proteins in a cell needed to start transcription in eukaryotic cells are activated using this molecule.

a)

Transcription factor

b)

Signal molecule

c)

Phosphate

51.

This laboratory procedure is known as

a)

CLONING

b)

gel electrophoresis

c)

chromatography

d)

use of a dichotomous key

52.

In preparation for an electrophoresis procedure, enzymes are added to DNA in order to

a)

convert the DNA into gel

b)

cut the DNA into fragments

c)

change the color of the DNA

d)

produce longer sections of DNA

53.

A student performed a gel electrophoresis experiment. The results are represented in the diagram

below. Compared to the fragments at the top of the gel, the fragments at the lower end are

a)

larger, and move slower

b)

larger, and move faster

c)

smaller, and move faster

d)

smaller, and move slower

54.
What applications can gel electrophoresis be used for?
a)
Parental Testing
b)
Criminal Investigations
c)
Sequence Endangered Species DNA
d)
All of the above
55.
In gel electrophoresis, the largest DNA fragment will appear
a)
closest to the starting wells
b)
farthest from the starting wells
c)
three quarters away from the starting wells
d)
it depends on how many fragments there are
56.
Based on these results whose blood was found in the blood stain at the crime scene?
a)
Bob
b)
Sue
c)
John
d)
Lisa
57.
Which suspect is linked to the crime scene by this DNA analysis
a)
Suspect A
b)
Suspect C
c)
Suspect D
d)
Suspect B
58.
Shannon does not know who her father is.  There are three possibilities:  Jack, Daniel and Bill.  Who is the father?
a)
Jack
b)
Daniel
c)
Bill
59.
Which two bear species are most closely related?
a)
Bear 1 and Bear 2
b)
Bear 1 and Bear 3
c)
Bear 2 and Bear 3
d)
There’s no way to tell
60.

Which of these choices most closely explain to how CRISPR technology works to allow scientists to edit a genome?

a)

"shake and bake"

b)

"cut and paste"

c)

"hide and seek"

d)

"live and love"

61.

UGU

a)

Cysteine

b)

Arginine

c)

Glutamine

d)

Methionine

e)

Glycine

62.

CGU

a)

Cysteine

b)

Arginine

c)

Glutamine

d)

Methionine

e)

Glycine

63.

CAG

a)

Cysteine

b)

Arginine

c)

Glutamine

d)

Methionine

e)

Glycine

64.

AUG

a)

Cysteine

b)

Arginine

c)

Glutamine

d)

Methionine

e)

Glycine

65.

GGU

a)

Cysteine

b)

Arginine

c)

Glutamine

d)

Methionine

e)

Glycine

66.

What is the name of the lab tool you used to put dyes into the wells of an electrophoresis gel?

a)

micropipette

b)

transfer pipette

c)

graduated cylinder

d)

serological pipette

67.
What charge is DNA?
a)
positive
b)
negative
c)
neutral
68.

In the electrophoresis of dyes lab, what charge did most dyes have?

a)

positive

b)

negative

c)

neutral

69.

In the electrophoresis of dyes lab, what side of the gel box did most of the dyes move towards?

a)

positive end

b)

negative end

70.

In the electrophoresis of dyes lab, why did the different dyes move at different speeds?

a)

some dyes were more charged than others

b)

some of the dyes were made of molecules were bigger than the others

c)

both the charge and the size of the dye molecules influenced the speed at which they moved.

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