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Alterations Of Cellular Function, Adaptation, and Genetics

Total questions: 55

Worksheet time: 31mins

Name
Class
Date
1.

What components are found in the nucleus of a eukaryotic cell? Select all that apply

a)

Golgi Apparatus

b)

RNA

c)

DNA

d)

enzymes required for replication and transcription

e)

organic molecules

2.

What cellular structure is important for regulating growth and proliferation?

a)

Ribosomes

b)

plasma membrane

c)

ATP

d)

The Golgi Apparatus

e)

essential oils

3.

Which organelles are responsible for protein synthesis and packaging? Select all that apply

a)

The Golgi Apparatus

b)

Mitochondria

c)

Ribosomes

d)

Plasma Membrane

e)

RNA

4.

A disease that targets the peroxisomes would have difficulty performing which cellular duty? Select all that apply

a)

Protein synthesis and packaging

b)

Inability to perform apoptosis

c)

inability to produce bile acids in the liver

d)

inability to perform oxidation reactions

5.

A dysfunction with the mitochondria might affect the cell's ability to do: Select all that apply

a)

regulate apoptosis

b)

perform aerobic respiration

c)

packaging proteins and sending them out of the cell

d)

regulating the production of ATP

6.

How many ATP are created from 2 molecules of glucose in anaerobic respiration?

a)

2

b)

4

c)

36

d)

72

7.

How many ATP molecules are made for 1 glucose molecule undergoing cellular respiration in aerobic conditions?

a)

approximately 36

b)

approximately 20

c)

approximately who cares

d)

approximately 129

8.

How many ATP are made before the ETC (assuming the cell is under aerobic conditions) for one glucose molecule?

a)

4 ATP

b)

2 ATP

c)

32 ATP

9.

A cell that uses a G protein linked receptor to make a cellular response, which of the following is incorrect? Select all that apply

a)

The cell would need a amplifier enzyme to stimulate a secondary response

b)

The cell would need an extracellular hormone to stimulate the G protein linked receptor

c)

The cell would need an intracellular hormone to stimulate the G protein

d)

The cell will likely use a second messenger system to amplify the response

10.

Which cell communication uses rapid signaling that is used by muscle cells and nerve impulses?

a)

G protein-linked receptors

b)

Ion channel linked receptors

c)

911

d)

Intracellular receptors

11.

What are the three mechanisms of membrane transport? Select all that apply

a)

diffusion

b)

osmosis

c)

active transport

d)

vesicular transport

e)

MARTA

12.

Diffusion is a passive process. What helps determine the rate of diffusion? Select all that apply.

a)

Relative concentrations of the solutes on either side of the membrane

b)

the amount of ATP in circulation

c)

the amount of ADP in circulation

13.

True or false: Facilitated diffusion involves passing or a molecule through a transporter against their concentration gradient

a)

True

b)

False

c)

Tralse

d)

Depends

14.

True or false: Water moves from an area of lower concentration solutes to a higher concentration of solutes

a)

True

b)

False

15.

In order to have membrane potential what is needed? Select all that apply:

a)

Different concentrations of ions across the membrane

b)

permeability to the ion

c)

semipermeable membrane

d)

resting potential

16.

At resting membrane potential, which ion is more permeable across the plasma membrane?

a)

potassium

b)

sodium

c)

ATP

17.

During a action potential, what ion is the plasma membrane more permeable to?

a)

sodium

b)

potassium

18.

What is the Nernst potential? Select all that apply

a)

is discussed in context with membrane potentials

b)

is discussed in context with the electron transport chain

c)

determined by the ratio of the concentration of a specific ion on the two sides of the membrane

d)

determined by the ratio of the concentration of water on two sides of the membrane

19.

What are characteristics of the Na/K pump? Select all that apply

a)

moves sodium from inside the cell to the extracellular region where the concentration of sodium is greater

b)

moves potassium from outside the cell to inside the cell where it's concentration is greater

c)

is a form of secondary active transport

d)

is a form of primary active transport

e)

moves potassium from inside the cell to outside the cell where it's concentration is greater

20.

How does water get into the cell?

a)

aquaporins

b)

through the plasma membrane without assistance

c)

through a secondary transporter

21.

What are the four categories of the tissues?

a)

epithelial, cardiac, nervous, areolar

b)

adipose, connective, muscle, epithelial

c)

epithelial, connective, muscle, nervous

d)

Puffs ultra soft and strong, kleenex lotion with aloe infusion, Walmart brand, Target brand

22.

A client has suffered nerve damage in his right arm. What can the nurse expect to happen to muscles in his arm?

a)

Increase in size (hypertrophy) as the cells adapt to change

b)

Decrease in the size of the cells (atrophy)

c)

Stay the same

d)

Increase their proliferation cycle to revert cells back to original form

23.

True or false: The afferent neuron carries sensory information from the stimulus to the CNS and the efferent neuron carry information away from the CNS and is involved in receptory information from the external environment

a)

True

b)

False

c)

Tralse

24.

What is the function of epithelial tissue? Select all that apply

a)

filtration

b)

protection

c)

insulating

d)

conduction of electricity

25.

What is neuroglia? Select all that apply:

a)

Astrocytes, neurons, microglia, ependymal cells

b)

oligodendrocytes, afferent neurons, astrocytes

c)

cells that support the neurons, form myelin, and have tropic/phagocytic response

d)

astrocytes, oligodendrocytes, microglia, and ependymal cells

26.

What cells myelinate the peripheral nervous system?

a)

Schwann cells

b)

Oligodendrocytes

c)

Astrocytes

d)

Microglia

27.

What are the types of cell junctions? Select all that apply

a)

Continuous tight junction

b)

Adhering junction

c)

Gap junction

d)

conjunction junction what's your function

e)

spaghetti junction

28.

True or false: The cell junctions are important in governing the shape of the body, transmitting mechanical stress from one cell to another, and creating pathways for communication

a)

True

b)

False

29.

What cellular junction is important in connecting cytoplasms of cells to maintain cell to cell conduction, and where would this be important to have?

a)

adhering junction; the heart

b)

adhering junction; the neurons

c)

continuous tight junction; the smooth muscles of the intestines

d)

gap junction; the heart

30.

If a client has been fitted for a cast to the right arm, what can you expect the cellular adaptation would result from?

a)

atrophy

b)

physiologic atrophy

c)

disuse hypertrophy

d)

compensatory hypertrophy

e)

hypertrophy

31.

Competitive athletes might have enlarged hearts as a result of which cellular adaptation?

a)

compensatory hypertrophy

b)

physiologic hypertrophy

c)

adaptive hypertrophy

d)

pathological hypertrophy

32.

What is an example of compensatory hypertrophy?

a)

kidney transplant leaving the donor with one good kidney

b)

increased workout routine overtime leading to increased heart size

c)

myocardial hypertrophy fro valvular heart disease

d)

regeneration of a liver after surgery

33.

What cellular adaptations allows stressed tissues to survive or maintain function? Select all that apply

a)

Metaplasia

b)

Dysplasia

c)

Atrophy

d)

Hyperplasia

e)

Hypertrophy

34.

What is an example of hormonal hyperplasia?

a)

A patient who has cervical dysplasia confirmed through a pap test

b)

A patient who recently donated their liver and their liver is slowly starting to regrow

c)

A pregnant woman who has increased breast size and uterine tissue growth

d)

A patient who use to have ciliated columnar cells in their esophagus but due to smoking has altered the cells but still able to function

35.

What is an example of dysplasia?

a)

A smoker who has had changes to the cells in their airway

b)

A patient who tests positive for cervical dysplasia through a pap test

c)

A patient who has been diagnosed with endometrial hyperplasia

36.

If a cell is under stressed, what types of intracellular accumulations might occur? Select all that apply:

a)

build up of lipids, proteins, and pigments which are all considered abnormal body substances

b)

abnormal exogenous substances such as tattoo ink and pigments

c)

abnormal endogenous substances such as metabolic products consisting of glycogen and lipids

37.

What are examples of agents that can lead to cell injury. Select all that apply

a)

electricity

b)

radiation

c)

using sunscreen

d)

nutritional imbalances

e)

drinking excess tequila and doing "OTC" drugs to cope for this exam

38.

What happens in the state of oxygen depletion? Select all that apply

a)

The cell would continue to make 32 ATP per 1 molecule of glucose

b)

The cell would have increased build up of lactic acid

c)

Decreased activity of the Na/K pump

d)

Decrease glycogen storage available

39.

What does ROS stand for in pathophysiology? (More than three potential answers could be applied but chose the most correct one)

a)

Review of Systems

b)

Reactive Oxygen Species

c)

Rhinos on Steroids

d)

Release of Students

40.

What is true about reactive oxygen species? Select all that apply

a)

They can decrease the amount of ATP being made in the ETC by attacking pyruvate at the end of glycolysis

b)

They are reactive and unstable

c)

They destroy the lipid molecules in the cell membranes which can potentially destroy membrane permeability and potentially nucleic acids in the cell

d)

The Golgi Apparatus is responsible for helping decrease and stabilize the ROS along with peroxisomes

e)

ROS are naturally generated but are usually balanced by an antioxidant system

41.

An example of an exogenous antioxidant system would be: Select all that apply

a)

blueberries

b)

superoxide dismutase

c)

tequila

d)

peroxisomes

e)

strawberries

42.

What is one clinical manifestation of hypoxia leading to ATP depletion or "power failure"

a)

Na/K pump activity declining

b)

edema

c)

sepsis

d)

death, RIP

43.

True or false: Cells usually maintain low cytosolic calcium

a)

True

b)

False

44.

If a cell is injured, what are the potential cascade of effects that can occur? Select all that apply:

a)

a cell's injury can be reversed if remove insult in timely fashion

b)

apoptosis

c)

necrosis

d)

cell swelling

e)

programmed cell removal

45.

The signal of the death domain in apoptosis is known as what pathway?

a)

The intrinsic pathway

b)

The star wars pathway

c)

The extrinsic pathway

d)

The AMSN pathway

46.

What is the clinical presentation of dry gangrene

a)

A non-diabetic patient who lacks arterial blood flow but allows venous return that will carry fluid out of the tissue which will present as dry, shrinks, skin wrinkles

b)

A diabetic patient who lacks venous flow thus allowing the fluids to accumulate in the tissue which leads to cold, swollen, pulseless, moist, black, malodorous odor

c)

A patient who has a clostridium infection

47.

Why do cells change with age? Select all that apply

a)

Telomeres are shortening thus increasing cell genome disruption

b)

glycation

c)

Point mutations

d)

DNA damage

48.

What is a gene?

a)

A sequence of RNA that contains the instructions for making a enzyme

b)

Sequence of DNA nucleotide sequences that contain the instructions to make a protein

c)

Made of denim

49.

True or false: Repression turns a gene off and induction regulates the "off" switch of the gene

a)

True

b)

False

50.

An example of epigenetics would be: Select all that apply

a)

environmental factors

b)

change in DNA sequence

c)

DNA methylation

d)

Histone modification

51.

True or false: All cells have all the same genes but only certain genes are turned on

a)

True

b)

False

52.

True or false: If you have only one copy of the gene you are considered heterozygous

a)

True

b)

False

c)

I hate genetics

53.

What is a locus?

a)

a flower

b)

a pest

c)

a position on a chromosome to represent a protein

d)

a position of a gene on a chromosome

54.

What is not true of gene interactions?

a)

many genes could affect one trait known as polygenic

b)

two genes together might create a new phenotype known as complementary

c)

one gene could mask the effect of another known as epistasis

d)

the ability of gene to express its function is known as penetrance

e)

the degree of phenotype expression is known as expressivity

55.

The Renin Angiotensin Aldosterone Pathway is an example of:

a)

Homeostasis

b)

Allostasis