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Genetics 3.1 - 3.3

Total questions: 40

Worksheet time: 24mins

Name
Class
Date
1.
Which of the following is an inherited disease that is due to a base substitution mutation in a gene?
a)
Trisomy 21
b)
Sickle cell anemia
c)
AIDS
d)
Type II Diabetes
2.
What is the cause of sickle-cell anemia?
a)
A change to the base sequence of a hemoglobin gene
b)
Mosquitos acting as the vector for malaria
c)
Iron deficiency due to the malaria parasite
d)
Production of more white blood cells than red blood cells by bone marrow
3.
Which of the following statements about homologous chromosomes is correct?
a)
Each gene is at the same locus on both chromosomes
b)
They are two identical copies of a parent chromosome which are attached to one another at the centromere
c)
They always produce identical phenotypes
d)
They are chromosomes that have identical genes and alleles
4.
What happens in crossing over?
a)
Exchange of genes during metaphase of mitosis
b)
Random distribution of chromosomes during meiosis
c)
Exchange of genetic material between homologous chromosomes
d)
Homologous chromosomes fail to separate during meiosis
5.
If the haploid number of a species is 14, how many chromatids will there be in metaphase I in a dividing diploid cell?
a)
7
b)
14
c)
28
d)
56
6.
How many autosomes are there in a human sperm?
a)
1
b)
22
c)
23
d)
46
7.
In the diagram, which pair represents homologous chromosomes?
a)
1 and 2
b)
3 and 4
c)
2 and 5
d)
4 and 6
8.
What does the karyotype below correspond to?
a)
A normal male
b)
A normal female
c)
A female with Down Syndrome
d)
A male with Down Syndrome
9.
What can be concluded from the karyotype  provided below?
a)
There was non-disjunction during meiosis in the mother.
b)
There was non-disjunction during meiosis in the father.
c)
The fetus is male.
d)
The fetus is female.
10.
Each identical side of a chromosome is the 
a)
centromere
b)
chromatin
c)
centriole
d)
chromatid
11.
Autosomes are
a)
chromosomes found in autotrophs, only
b)
chromosomes that automatically correct all errors in the DNA
c)
chromosomes that determine traits other than sex
d)
chromosomes that determine the sex of the individual
12.

An organism's reproductive cells, or sex cells, are called _____.

a)

bacteria

b)

prokaryotes

c)

gametes

d)

pathogens

13.

Chromosomes that are paired by size and content are called _______ chromosomes.

a)

homeostasis

b)

homologous

c)

matching

d)

sister

14.

Body cells are also called _________ cells.

a)

normal

b)

prokaryotic

c)

pathogens

d)

somatic

15.

Cells that contain 2 sets of chromosomes are called _________ (2n).

a)

diploid

b)

haploid

c)

triploid

d)

polyploid

16.

The 23rd pair of chromosomes that do determine the sex of an individual are called ___________.

a)

sex chromosomes

b)

autosomes

c)

homologous

d)

genes

17.

A photo of the chromosomes in a dividing cell that are arranged by size is called a _________.

a)

mutation

b)

gene

c)

picture

d)

karyogram

18.
Identify the phase:
a)
Metaphase I
b)
Metaphase II
c)
Anaphase I
d)
Anaphase II
19.
Identify the phase.
a)
Metaphase I
b)
Metaphase II
c)
Anaphase I
d)
Anaphase II
20.
After meiosis II the daughter cells will contain ____ chromosomes if the original cell contained 78.
a)
78
b)
39
c)
23
d)
46
21.
In mitosis cells are genetically _______, but in meiosis cells are genetically ______.
a)
diverse, identical
b)
identical, diverse/different
22.
In sexual reproduction, chromosome reduction is necessary to ___.
a)
ensure that all offspring have the correct diploid number of chromosomes
b)
ensure that all offspring have the correct haploid number of chromosomes
c)
ensure that all daughter cells are identical
23.

What does the karyogram show?

a)

A normal male

b)

A normal female

c)

A male with Down syndrome

d)

A female with Down syndrome

24.

What is a gene locus?

a)

An organism's entire genome

b)

A detrimental genetic mutation

c)

The position of a chromosome within a karyogram

d)

The position of a specific gene on a chromosome

25.

What is a possible source of the chromosomes used for pre-natal karyotype diagnosis?

a)

The mother's lymphocytes.

b)

The mother's cheek cells.

c)

The cells from the chorionic villi.

d)

The fetal hair root cells.

26.

What causes the presence of three chromosomes 21 in Down syndrome?

a)

Crossing over

b)

Allele change

c)

Non-disjunction

d)

Gene mutation

27.

Which best describes the process shown?

a)

mutation in which the DNA content of the gene is altered

b)

segregation of sister chromatids

c)

condensation and segregation of the alleles

d)

crossing-over in which alleles are exchanged

28.
Which of the following represents chromosome # during fertilization?
a)
n+n=2n
b)
n=n
c)
2n=n+n
d)
2n=2n
29.
Based only on the sex chromosomes in typical human egg and sperm cells at fertilization, the probability of producing a female is
a)
25%
b)
50%
c)
75%
d)
90%
30.
Body cells of fruit flies contain 8 chromosomes.  Scientists used studies of flies to discover how egg and sperm are formed. What did they observe?
a)
Body cell of offspring flies have 16 chromosomes
b)
Sperm cells have 8 chromosomes
c)
Egg cells have 4 chromosomes
d)
Body cells of offspring have 4 chromosomes
31.
What is one advantage of sexual reproduction?
a)
offspring are identical to parents
b)
offspring are resistant to viruses
c)
offspring are born live, rather than from eggs
d)
offspring inherit a wider variety of genetic information
32.
Crossing over helps promote 
a)
male genotype
b)
genetic variation
c)
DNA replication
d)
mitosis
33.
A human zygote should have _____ chromosomes inside.
a)
46
b)
23
c)
92
d)
64
34.

What can you say about this individual?

a)

Trisomy 13

b)

Monosomy 21

c)

47, XXY

d)

Trisomy 21

35.
The process of crossing over occurs in what phase of meiosis?
a)
anaphase 1
b)
prophase 1
c)
prophase 2
d)
telophase 1
36.
The nuclear membrane dissolves during
a)
Prophase
b)
Metaphase
c)
Anaphase
d)
Telophase
37.
What phase is shown here?
a)
Metaphase II
b)
Telophase I
c)
Telophase II
d)
Metaphase I
38.

What phase is shown here?

a)

Prophase II

b)

Prophase I

c)

Anaphase II

d)

Interphase I

39.
What phase is shown here?
a)
Anaphase I
b)
Prophase I
c)
Metaphase II
d)
 Metaphase I
40.
What phase is shown here?
a)
Telophase I
b)
Metaphase II
c)
Telophase II
d)
Anaphase I

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