It involves the response of the coagulation factors during vascular injury.

1. Hemostasis comes from Greek; "Hemo" means "Blood" and "Stasis" means ________.

In megakaryopoiesis, megakaryoblast contains cytoplasmic granules.

Megakaryocytes have already visible thrombocytes.

Metamegakaryocyte contains cytoplasmic tags or blunt protrusions of cytoplasm extending into its external environment.

Circulating, inactive platelets have _____ shape.

Hemostasis is:

Megakaryocyte maturation series: Mature to Immature

I. Metamegakaryocytes II. Megakaryoblasts

III. Promegakaryocytes IV. Megakaryocytes

Cytoplasmic Tags in Promegakaryocytes.

The stage of Megakaryopoiesis where Demarcating Membrane System (DMS) is first formed.

Substances involved in Primary Hemostasis.

I. Platelets

II. PK

III. Blood vessels

IV. Tissue Thromboplastin

Megakaryocytic Cell series or maturation is done at what site?

What is the specimen of choice to visualize and study the different Megakaryocytic cells?

What is the nuclear feature of Promegakaryocytes?

Which of the following is true?

Patients with which of the following diseases may have a normal PTT?

A twenty-seven year-old woman complains of heavy menstrual periods, ease of bruising and excessive bleeding following a dental procedure. She has a normal platelet count, normal PT, but slightly prolonged aPTT. Of the following, the test that will most likely make the diagnosis is.

Features of the antiphosopholipid syndrome include all of the following except

von Willebrand factor adheres platelets to exposed subendothelial collagen via

Platelets aggregate with each other with the help of fibrinogen that binds to

thrombin activates following factors, except

clot retraction is mediated by

antithrombin inhibits the following except

urokinase activates

A 7 year old girl requiring a tonsillectomy and adenoidectomy undergoes pre-operative laboratory testing by her surgeon revealing a prolonged activated partial thromboplastin time (PTT) of 150 seconds (normal range 22-36 seconds). Her prothrombin time (PT) is normal. She had previously had 2 dental extractions that were uneventful. She otherwise has no personal or family history of bleeding. Which of the following is most likely:

A 1 year old male presents to the emergency room with irritability and vomiting, and a CT scan demonstrates a large intracranial parenchymal hemorrhage. The mother reports that his only other bleeding symptom was prolonged bleeding from the umbilical stump. The patient comes from a large pedigree with numerous male and female first and second degree relatives, however there is no history of excessive bleeding in any of them. Which of the laboratory test patterns are most consistent with this history?

A 34-year-old man with limited medical history presents with recurrent epistaxis and prolonged bleeding following a dental extraction. He notes a history of easy bruising. His nose bleeds last for up to an hour and he has required medical intervention on several occasions to control the bleeding. A complete blood count (CBC) shows mild thrombocytopenia (134 x 109/L) but is otherwise normal. Prothrombin time (PT) and partial thromboplastin time (PTT) are normal. Review of the peripheral blood smear shows giant platelets. Which of the following is most likely to support the diagnosis?

Which factor has shortest half-life?

Joint hematoma (hemarthosis) can be seen in all, except