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Topic 4: Enzyme kinetics

Total questions: 8

Worksheet time: 4mins

Name
Class
Date
1.

What is the role of Michaelis-Menten equation?

a)

To calculate the free energy

b)

Mathematically explain the relationship of enzyme's velocity and the substrate concentration

c)

Mathematically explain the saturation of enzyme in substrate

2.

What is the meaning of these terms: E, S, ES

a)

Respectively for Enzyme's effectiveness, Substrate, and complex of enzyme-substrate

b)

Respectively for Enzyme, Substrate, and Enzyme-Substrate complex

3.

What is the meaning of these terms: [E], [S], [ES]

a)

Respectively for concentration of enzyme, concentration of substrate, and concentration of enzyme-substrate complex

b)

Respectively for amount of enzyme, concentration of substrate, and concentration of enzyme-substrate complex

4.

 Velocity, V=d[P]dtVelocity,\ V=\frac{d\left[P\right]}{dt}  is the equation for enzyme's velocity. Which of the following information are correct? 

a)

Velocity is the rate of product formation over time

b)

Velocity is a measurement of rate

c)

Velocity measures the depletion (kekurangan) of the substrate

d)

Velocity measures the formation of the product

5.

Select the correct statement(s) related to Michaelis-Menten plot (graph)

a)

At zero concentration of substrate, meaning [S]=0, the velocity is zero

b)

As the concentration of the substrate increases, the formation of product also increases

c)

The plot is generating using different concentration of substrate

d)

The plot is generating using different concentration of enzyme

6.

What is Vmax?

a)

With a fix concentration of enzyme, the formation of product will not increase even if you add more substrate

b)

A maximum value for Velocity

c)

Related to a situation where the Michaelis-Menten plot reaches a plateau ('flat')

d)

Maximum substrate that is been converted to product

7.

What is Km?

a)

The unit for length is cm. The unit for Km is substrate concentration

b)

Km is the value of [S] when the velocity is half Vmax

c)

Km is kilometer, how far the enzyme can move

d)

Km is Michaelis-Menten constant

8.

Affinity is a word to describe how effective is the binding between the enzyme and the substrate. What is the relationship of Km with affinity?

a)

High Km, High affinity

b)

High Km, Low affinity

c)

With lower Km, the enzyme can reach Vmax faster