WorksheetsPharmacology Review
Total questions: 15
Worksheet time: 11mins
Controlled substances in schedule _____ require a written prescription with the provider's signature and do not permit refills.
II, III, IV
II, III
II only
III only
Which of the following statements is true regarding the therapeutic index (TI) of a drug?
A drug with a large TI is more dangerous than a drug with a small TI.
The formula for TI is ED50/LD50.
ED50 is 50% of the effective clinical dose.
TI is the ratio of the median lethal dose to the median effective dose
Which of the following is true regarding basic principles of drug distribution in the bloodstream?
All drugs in the blood are either bound to plasma proteins or free
Only the drug that is bound to plasma proteins can exert the pharmacologic effect
Only the drug that is bound to plasma proteins can pass across cell membranes
The free drug is a reservoir for the drug
Which of the following is (are) true when tubular urine is more acid?
Weak acids are excreted more rapidly
Weak bases are excreted more rapidly
Weak acids are excreted more slowly
Both a and b are true
Both b and c are true
An acute, life-threatening allergic reaction characterized by hypotension, bronchospasm, laryngeal edema, and cardiac arrhythmias is what type of hypersensitivity
Type I
Type II
Type III
Type IV
The anatomy of what system contains long preganglionic nerves and short postganglionic nerves
Somatic
Sensory
Parasympathetic
Sympathetic
When the SANS is stimulated, the adrenal _____ releases primarily _____ into the systemic circulation.
Cortex; epinephrine
Cortex; acetylcholine
Medulla; epinephrine
Medulla; acetylcholine
Which of the following substances will block the action of acetylcholine at the postganglionic endings in the parasympathetic autonomic nervous system (PANS
Acetic Acid
Pilocarpine
Atropine
epinephrine
Which of the following statements is true concerning direct- and indirect-acting cholinergic agents
A direct agent causes release of neurotransmitter and an indirect agent acts on the receptor
The indirect-acting agents include the choline derivatives and pilocarpine
The indirect-acting cholinesterase inhibitors act by stimulating release of acetylcholine
Indirect- acting agents Inhibit the enzyme that normally destroys acetylcholine- results in stimulation of the PANS
The direct effect of acetylcholine on the heart is _____ chronotropic and _____ inotropic
positive; positive
negative; negative
positive; negative
negative; positive
Which of the following classes of antiarrhythmics is associated with gingival enlargement
Na+ Channel Blockers
K+ Channel Blockers
Ca+ Channel Blockers
Beta Blockers
Which of the following agents has the most serious drug interaction with warfarin?
Omeprazole
Aspirin
Digitalis
Lomotil
A key side effect that angiotensin-converting enzyme inhibitors (ACEIs) have that angiotensin receptor blockers do not have is nonproductive cough
True
False
The action of nonopioid analgesics is related to their ability to inhibit
The CNS
Release of epinephrine
Release of acetylcholine
Prostaglandin Synthesis
Which of the following opioids is used primarily in the treatment of opioid addicts
Propoxyphene
Meperidine
Hydrocodone
Methadone
