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WorksheetsMIXTISQUE 1
Total questions: 74
Worksheet time: 43mins
Which of the following is diffusion limited gas
O2
CO2
CO
none
which of the following causes left shift of ODC
2,3 BPG
increase in temperature
increase in ph
Anemia
Venous blood with high hematocrit is seen in:
RBC high chloride
Plasma high Na
Plasma high HCO3
. RBC high K
Haldane effect
Effect of 2,3-BPG
Dissociation of CO2 on oxygenation
Dissociation of O2 on oxygenation
Chloride shift
Percentage of O2 carried in chemical combination
97
66
3
7
The fraction of inspired air in mouth to-mouth respiration is
0.16
0.20
0.24
0.21
Arterial O2 content is reduced in one of the following
stagnant hypoxia
Anemic hypoxia
Histotoxic hypoxia
Ischemic hypoxia
Oxygen therapy is least useful in:
Anemia
ARDS
Alveolar damage
COPD
Which of the following variants of hypoxia does not stimulate peripheral chemoreceptors?
Hypoxic hypoxia
Anaemic hypoxia
Stagnant hypoxia
Histotoxic hypoxia
Which of the point on the following figure represent arterial blood in severely anemic person?
Point E
Point B
Point C
Point D
While doing thoracocentesis it is advisable to introduce needle along
Upper border of the rib
Lower border of the rib
In the centre of intercostal space
In the anterior of intercostal space
Structure not passing through the oesophageal hiatus
Left phrenic nerve
Right vagus nerve
Left vagus nerve
Left gastric artery
Anterior diaphragmatic hernia is through
Oesophageal opening
Para oesophageal opening
Foramen of morgagni
Bochdolek foramen
Bochdolek's hernia occurs through
Anteromedial part of diaphragm
Posterolateral part of diaphragm
Central tendon of diaphragm
Hiatus hernia
True about Anterior Intercostal Artery
Present in 1st to 11th space
Each Intercostal space has two arteries
Branch of internal thoracic artery
Branch of Aorta
Right superior Intercostal vein drains to
Brachiocephalic vein
Azygos vein
IVC
None
Level of lower border of lung at mid axillary line is
6th rib
8th rib
10th rib
12th rib
Aal of the following are characteristics of Bronchopulmonary segments except
It is surgically resectable
It is named according to the segmental bronchus supplying it
It is drained by independent intrasegmental veins
It is largest subdivision of a lobe
The normal narrowing of the middle of oesophagus is caused by
Azygos vein
Hemiazygous vein
Right main stem bronchus
Left main stem bronchus
An inhaled foreign body is likely to lodge in the right lung for all except
Right bronchus is more vertical then left bronchus
Tracheal bifurcation directs the foreign body to right
Right lung is shorter and wider then left
Right inferior bronchus is in continuation with right principal bronchus
The root of right lung does not lie behind
Right atrium
Right vagus
Superior vena cava
Phrenic nerve
The root of right lung does not lie behind
Right atrium
Right vagus
Superior vena cava
Phrenic nerve
Vitamin K is involved in the post-translational
modification of
Glutamate
Lysine
Aspartate
Proline
Which of the following is true about vitamin K?
Vit K dependent factors undergo post-tran-
scriptional modification
Prothrombin is a vitamin K dependent factor
Stuart-Prower factor is not vitamin K
dependent
Menadione is a natural water insoluble vitamin
K used in clinical practice
Biotin act as a coenzyme for all except:
Pyruvate to Oxaloacetate
Acetyl CoA to Malonyl CoA
Propionyl CoA to Methyl Malonyl CoA
Glutamate to Gamma Carboxy Glutamate
A vitamin derived from amino acid is
Biotin
Pantothenic acid
Niacin
Folic acid
Vitamin for which RDA is based on protein
intake is:
Niacin
Riboflavin
Pyridoxine
Thiamine
Which of the vitamin deficiency lead to lactic
acidosi
Riboflavin
Niacin
Thiamine
Pantothenic
Vitamin which is excreted in urine
Vitamin A
Vitamin C
Vitamin D
Vitamin K
Thiamine deficiency causes decreased energy
production because:
t is required for the process of transamination
It is a cofactor in oxidative reduction
It is a coenzyme for transketolase in pentose
phosphate pathway
t is a coenzyme for pyruvate dehydrogenase
and alpha ketoglutarate dehydrogenase
Not needed in TCA cycle:
Pyridoxine
Thiamine
Niacin
Niacin
Identify the vitamin deficiency:
(
Riboflavin
Niacin
Ascorbic Acid
Biotin
The form of THFA used in treatment is:
N10 Formyl THFA
N5 Formyl THFA
N 5 Formimino THF
N5 Methyl THFA
Excess of avidin causes deficiency of:
Biotin
Choline
Vitamin B12
Folate
Thiamin act as a cofactor in
Malonate to Oxaloacetate
Pyruvate to Oxaloacetate
Succinate to Fumarate
Pyruvate to Acetyl CoA
The given coronary artery angiogram is from a 68-year-old man with recurrent angina. It reveals 90% stenosis of the left anterior descending (LAD) artery, indicated by the white arrow. Based upon this finding, which portion of the heart is most likely susceptible to ischemic damage?
Anterior two thirds of interventricular septum
Posterior one third of interventricular septum
Atrioventricular (AV) node
Diaphragmatic surface of left ventricle
Sebhoreic Dermatitis is produced by deficiency
of:
Vitamin A
Vitamin B1
Vitamin B2
Vitamin C
Severe thiamine deficiency is associated with:
Decreased RBC transketolase activity
Increased clotting time
Decreased RBC transaminase activity
Increased xanthurenic acid excretion
A child is born at home without difficulty. Two weeks later, the mother takes the infant to her doctor, reporting that he “turns blue” when he cries. Physical examination reveals the infant is cyanotic and has a distinct systolic heart murmur. The physician suspects the baby has a tetralogy of Fallot (TOF). Which of the following conditions is a component of this syndrome?
Transposition of the great vessels
Hypertrophy of the left ventricle
Interatrial septal defect
Pulmonary infundibular stenosis
A 22-year-old woman gives birth to an infant with an abnormally small coronary sinus that limits cardiac venous drainage. The coronary sinus is derived from which of the labeled structures in the given diagram of the primitive heart?
A
B
C
D
A 40-year-old man goes to his family physician for an annual examination. Which of the following locations is ideal for placement of the stethoscope for auscultation of the tricuspid valve of the heart?
E
B
C
D
A genetic coding defect in an early embryo results in absence of the lower part of the vertical portion of the cross of the endocardial cushions in the developing heart. Which of the following malformations is most likely present?
Atrial septal defect
Membranous ventricular septal defect (VSD)
Transposition of the great vessels
Muscular ventricular septal defect
One finding during autopsy of a newborn infant that died soon after birth is a significant ventricular septal defect at the upper end of the interventricular septum, as shown in the given photo. This malformation may have been related to maldevelopment of which of the following embryonic structures?
Septum secundum
Bulbus cordis
Endocardial cushions
Truncus arteriosus
A male baby is born with Down syndrome (trisomy 21) and associated cardiac defects. The given apical four-chamber view echocardiogram shows a complete atrioventricular canal defect that includes a primum atrial septal defect and a posterior inlet ventricular septal defect. What embryonic structures normally fuse to close the foramen primum?
Septum secundum and the septum primum
Septum secundum and the fused endocardial cushions
Septum primum and the fused endocardial cushions
Septum primum and the septum spurium
A 24-year-old man who has been overweight and sedentary most of his life experiences shortness of breath and cyanosis on exertion when he attempts to start an exercise program for the first time. A thorough physical examination by his physician reveals an aortic valve defect and an aortic murmur. This murmur is best detected with the stethoscope placed over which of the indicated sites?
A
B
C
D
E
A 15 year old male has polished rice as a major component of his diet.He us hospitalized with symptoms of poor appetite, peripheral neuropathy and muscular weakness. What is the probable disorder?
Pellagra
Beri beri
Anemia
Night Blindness
Which of the labeled structures in the given PA radiograph of the chest indicates the right atrium?A
B
C
D
A
E
A newborn infant has difficulty breathing and swallowing. Radiographic examination reveals constrictions of both the trachea and esophagus in the same plane. Which of the following congenital malformations is the most likely cause of this condition?
Double aortic arch
Persistent right 2nd aortic arch
Coarctation of the aorta
Patent ductus arteriosus
Persistent left 4th aortic arch
A small 3 year child was brought with bow legs , protruding forehead , pigeon chest , depressed ribs and kyphosis. The child is suffering from the deficiency of
Vitamin A
Vitamin D
Vitamin E
Vitamin K
Which of the following is not derived from vitamins
CoA
TPP
PLP
CoQ
Antihemorrhagic vitamin is
Vitamin A
Vitamin D
Vitamin E
Vitamin K
Which of the following is required for collagen synthesis
Folic acid
Ascorbic acid
Pantothenic acid
Nicotinic acid
Which of the following vitamins can be synthesized by a pathway that involved PLP and an aromatic amino acid
Vitamin B1
Vitamin B3
Vitamin B5
Vitamin D
Deficiency of which of the following may lead to hemolytic Anemia
Vitamin A
Vitamin D
Vitamin E
Vitamin K
Which of the following vitamin provides coenzyme for transamination reactions
Vitamin B3
Vitamin B6
Vitamin B9
Vitamin B12
Which of the following Vitamin act as a coenzyme for transfer of one carbon units?
Niacin
Thiamine
Folic acid
Pyridoxine
In a laboratory study, volunteers were made experimentally vitamin B6 deficient, and much to the investigator’s surprise, a mild hypoglycemia, with ketosis, was noted. The hypoglycemia is a result of which of the following?
Inhibition of phosphoenolpyruvate carboxykinase
Inhibition of pyruvate carboxylase
Reduced activity of glucose-6-phosphatase
Reduced activity of liver glycogen phosphorylase
Reduced insulin secretion
An individual has developed pancreatitis, and with it, steatorrhea. The patient also reports problems with his night vision, although visual acuity appears normal. Another expected finding in this patient would be which of the following?
Nystagmus
Easy bruising
Dermatitis
Orange tonsils
True about right atrium is
Related to central tendal of diaphragm at T10 level
Coronary sinus lies between fossa ovalis and IVC
SVC opening is guarded by endocardial valve
None
A 6-year-old girl has a history of seizures, which are only marginally relieved by standard medications. Switching her diet to which of the following may help her condition?
80% fat, 20% combined carbohydrate and protein, by weight
50% fat, 50% combined carbohydrate and protein, by weight
20% fat, 80% combined carbohydrate and protein, by weight
75% protein, 25% combined carbohydrate and fat, by weight
Boundary of KOCH triangle is not formed by
Tricuspid valve ring
Fossa ovalis
Coronary sinus
Tendon of todaro
The base of the heart is formed by
Right atrium
Left atrium
Right ventricle
Left ventricle
A patient has had a series of blood clots, and has been placed on warfarin to reduce such incidents. Warfarin exerts its effect by blocking which of the following?
Platelet biogenesis
Phospholipid synthesis
Clotting factor synthesis
Formation of γ-carboxyglutamate
The right coronary artery supplies all except
SA node
AV node
Right bundle branch
Left bundle branch
True about Ondine’s curse is:
Voluntary control of respiration is disrupted
Automated control of respiration intact
Seen in spinal poliomyelitis
Such patients can stay alive by breathing voluntarily
Administration of pure O2 to hypoxic
patients is dangerous because:
Apnea occurs due to hypo-stimulation of peripheral chemoreceptors
Pulmonary edema
DPG
Convulsions
Nitrogen narcosis is caused due to
Nitrogen inhibits dismutase
Increased production of nitrous oxide
Increased solubility of nitrogen in cell membrane
Decrease in oxygen free radicals
During acclimatization to high altitude all of the following take place except
Increase in minute ventilation
Increase in sensitivity of chemoreceptors
Increase in sensitivity of carotid body to hypoxia
Shift of oxygen dissociation curve to left
What will be the effect on respiration if a transmission is made between the
pons and medulla
Apnea
Irregular and gasping
No effect
Slow and deep
Moderate exercise tachypnea is due to stimulation of which receptor
Propioceptor
Lung receptor
J receptor
Barorecptor
A high-protein low-carbohydrate diet has, as its biochemical basis, the potential to lead to weight loss due to which of the following?
Allosteric inhibition of fatty acid synthesis
Increased glucagon release
Minimal insulin release
Reduced cortisol release
You are treating a patient with a fat malabsorption problem, and you suggest that the patient switch his or her diet to one that contains which of the following?
Triglycerides with long-chain fatty acids
Triglycerides with medium-chain fatty acids
Triglycerides with short-chain fatty acids
Triglycerides with a mixture of long-chain and short-chain fatty acids
A 42-year-old woman presents with tiredness and lethargy. She has tingling in her hands and feet. Blood work shows a macrocytic anemia, along with elevated homocysteine levels. One would also expect to see elevated levels of which metabolite?
Acetic acid
Ketone bodies
Methylmalonic acid
Propionic acid
V/Q is maximum at
Apex
Base
Middle lobe
None
