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WorksheetsGene Mutation
Total questions: 12
Worksheet time: 11mins
Name
Class
Date
1.
Any change in the sequence of DNA is...
a)
transgenic shift
b)
Single Genotype
c)
Monohybrid Trait
d)
Mutation
2.
What type of gene mutation has occurred here?
Normal DNA : T-G-A-C-C-A
Mutated DNA: T-G-A-C-C-A-A
a)
Base Substitution
b)
Base Deletion
c)
Base Insertion
d)
Frameshift
3.
DNA molecule segment is : TTACGCAAG
The mutated DNA segment is TTACGCAAC. This is an example of ___ mutation.
The mutated DNA segment is TTACGCAAC. This is an example of ___ mutation.
a)
Base Substitution
b)
Base Insertion
c)
Base Inversion
d)
Translocation
4.
Where do mutations occur?
a)
DNA and RNA
b)
DNA
c)
RNA
d)
mRNA and tRNA
5.
A nonsense mutation produced _________.
a)
Shorter polypeptide chain
b)
A slightly altered polypeptide chain
c)
A shift in the reading frame
d)
The regulatory sequence being altered.
6.
A base pair substitution can result in all of the following except __________.
a)
Missense mutation
b)
Frameshift Mutation
c)
Silent Mutation
d)
Nonsense mutation
7.
What kind of mutation is the result of an insertion?
a)
Silent Mutation
b)
Missense mutation
c)
Nonsense mutation
d)
Frameshift mutation
8.
This type of substitution codes for a stop codon
a)
Missense
b)
Nonsense
c)
Silent
d)
Deletion
9.
A type of substitution in which no amino acids change is called
a)
Missense
b)
Nonsense
c)
Silent
d)
Deletion
10.
Why are insertion and deletion (frameshift) mutations so harmful?
a)
They change all of the codons from the mutation on down the line, which changes the amino acid sequence
b)
They insert things that an organism doesn't need.
c)
They often delete things that organisms need.
d)
Insertion and deletions are not any more harmful than substitution mutations.
11.
Which of the following would result in a frameshift mutation?
a)
Insertions only
b)
Substitution only
c)
Deletion only
d)
Insertions and Deletions
12.
A type of substitution in which one amino acid changes is called
a)
Nonsense
b)
Missense
c)
Silent
d)
all of the above
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