Free Printable Chromosomal mutation

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Chromosomal mutation

Total questions: 25

Worksheet time: 20mins

Name

Class

Date

1.

What process occurs during meiosis that can result in chromosomal disorders?

a)

crossing over

b)

non-disjunction

c)

anaphase I

d)

prophase II

2.

A chromosome is found to be shorter than it's homologous match. Which type of mutation would this most likely be?

a)

insertion

b)

deletion

c)

translocation

d)

inversion

3.

Deletion

a)

When a segment of a chromosome breaks off.

b)

When a segment of a chromosome breaks off, flips, and reattaches.

c)

When a segment of a chromosome is copied or doubles.

d)

When a segment of a chromosome breaks and attaches to a non homologous chromosome.

e)

When entire chromosomes don't separate evenly during meiosis.

4.

Inversion

a)

When a segment of a chromosome breaks off.

b)

When a segment of a chromosome breaks off, flips, and reattaches.

c)

When a segment of a chromosome is copied or doubles.

d)

When a segment of a chromosome breaks and attaches to a non homologous chromosome.

e)

When entire chromosomes don't separate evenly during meiosis.

5.

Duplication

a)

When a segment of a chromosome breaks off.

b)

When a segment of a chromosome breaks off, flips, and reattaches.

c)

When a segment of a chromosome is copied or doubles.

d)

When a segment of a chromosome breaks and attaches to a non homologous chromosome.

e)

When entire chromosomes don't separate evenly during meiosis.

6.

Translocation

a)

When a segment of a chromosome breaks off.

b)

When a segment of a chromosome breaks off, flips, and reattaches.

c)

When a segment of a chromosome is copied or doubles.

d)

When a segment of a chromosome breaks and attaches to a non homologous chromosome.

e)

When entire chromosomes don't separate evenly during meiosis.

7.

Nondisjunction

a)

When a segment of a chromosome breaks off.

b)

When a segment of a chromosome breaks off, flips, and reattaches.

c)

When a segment of a chromosome is copied or doubles.

d)

When a segment of a chromosome breaks and attaches to a non homologous chromosome.

e)

When entire chromosomes don't separate evenly during meiosis.

8.

Inversion

a)

A

b)

B

c)

C

d)

D

9.

Duplication

a)

A

b)

B

c)

C

d)

D

10.

What are chromosomes 1-22 called?

a)

Autosomes

b)

Sex Chromosomes

c)

Chromotids

d)

Xenosomes

11.

What's the gender and disorder?

a)

Male - Downs Syndrome

b)

Female - Downs Syndrome

c)

Male - Turner Syndrome

d)

Female - Turner Syndrome

12.

What type of karyotype is shown here?

a)

Male with Turner Syndrome

b)

Male with Klinefelter Syndrome

c)

Female with Down Syndrome

d)

Female with Klinefelter Syndrome

13.

Trisomy 21 means that there are..

a)

Three copies of chromosome 21

b)

Twenty one copies of chromosome 3

c)

Three omies and 21 means

d)

Two copies of chromosome 21

14.

Cri-du-Chat Syndrome is caused by what kind of mutation?

a)

translocation

b)

inversion

c)

deletion

d)

addition

15.

Which of the following is an example of sex chromosomal aneuploidy?

a)

Down Syndrome (Trisomy 21)

b)

Edward Syndrome ( Trisomy 18)

c)

Patau Syndrome (Trisomy 13)

d)

Turner Syndrome (XO Female)

16.

A normal human has ___ pairs of autosomes and ___ pair(s) of sex chromosomes.

a)

23,1

b)

22,1

c)

1, 22

d)

1, 23

17.

An abnormal condition in which there are three homologous chromosomes in a set instead of two.

a)

Triploid

b)

Monosomy

c)

Trisomy

d)

Polyploid

18.

A human egg cell might contain

a)

22 autosomes and an X chromosome

b)

22 autosomes and a Y chromosome

c)

45 autosomes and an X chromosome

d)

45 autosomes and a Y chromosome

19.

Mutations can be

a)

beneficial

b)

harmful

c)

ineffective

d)

all of the above

20.

Chromosomal number alterations refer to....

a)

Changes in structure of chromosome

b)

Changes in sequence of bases in DNA

c)

Changes in numbers of chromosomes

d)

Changes in numbers of organisms

21.

Klinefelter syndrome is an example of ...

a)

Monosomy

b)

Trisomy

c)

Allopolyploidy

d)

Autopolyploidy

22.

When undergoing allopolyploidy, the hybrid is sterile... How do you make it fertile?

a)

Crossing over

b)

Doubling the chromosome number

c)

Undergo meiosis

d)

Autopolyploidy

23.

Which term refers to a picture of an individual’s chromosomes, used to detect genetic conditions?

a)

synapsis

b)

tetrad

c)

centriole

d)

karyotype

24.

What is the only condition we studied that is a monosomal disorder?

a)

Klinefelters

b)

Down's

c)

Turners

d)

XYY

25.

By looking at the chromosomes how can you tell that this person is biologically female?

a)

Because there are two X chromosomes

b)

Because there are more chromosomes than in a male

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