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[Revision] Centrifugation

Total questions: 27

Worksheet time: 14mins

Name
Class
Date
1.

How might solid sodium carbonate be obtained from sodium carbonate solution?

a)

Centrifugation

b)

Filtration

c)

Evaporation

d)

It cannot be extracted

2.

After centrifugation when sublimate settles, clear liquid

a)

can be allowed to rest

b)

can be allowed to form crystals

c)

can be decanted off

d)

can be evaporated

3.

After centrifugation, sublimate

a)

dissolves completely

b)

remain suspended in a liquid

c)

settles at bottom

d)

depends upon pH of sublimate

4.

Which of the following is an effective way of purifying liquids containing suspensions?

a)

crystallization

b)

decanting

c)

separating funnel

d)

centrifuging

5.

Fine insoluble solid particles can be removed through which of the following process?

a)

crystallization

b)

decanting

c)

centrifuging

d)

separating funnel

6.

Process quicker than filtration but not so effective is

a)

decanting

b)

centrifuging

c)

crystallization

d)

fractional distillation

7.

Differential centrifugation relies on the differences in ______ of biological particles of different

a)

Size, density

b)

Sedimentation rate, sizes and density

c)

Size, structure

d)

Mass, size

8.

Which of the following statements about the basic principle of sedimentation is False?

a)

The denser a biological structure is, the faster it sediments in a centrifugal field

b)

The more massive a biological particle is, the slower it moves in a centrifugal field

c)

The denser the buffer system is, the slower the particle will move in a centrifugal field

d)

The greater the centrifugal force is, the faster the particle sediments

9.

Which of the following is/are the application of analytical centrifugation?

I. The determination of the purity of macromolecules.

II. The determination of the relative molecular masses of solutes in their native state.

III. The examination of changes in the molecular mass of supramolecular complexes.

IV. The detection of conformational changes.

a)

I only

b)

I and II only

c)

I, II and III only

d)

I, II, III and IV

10.

Which of the following is/are appropriate care and maintenance of centrifuges?

I. Proper balancing of centrifuge tubes.

II. Avoid long time exposure of the rotors to alkaline solution and acidic buffers.

III. Cleaning centrifuges and rotors with coarse brushes and then wash them with distilled or de-ionized water after every run.

IV. For overnight storage, the rotors are left upside down and then positioned in a safe and dry place.

a)

I, II, III only

b)

II, III and IV only

c)

I, II, and IV only

d)

II only

11.

After centrifugation of milk, the supernatant is?

a)

Fat

b)

Whey

c)

Casein

d)

Water

12.

What is the name of the machine that spins in order to separate out components making up a mixture?

a)

Centrifuge

b)

Blood plasma

c)

Centrifugation

d)

Centrifugation tube

13.

How does centrifugation work?

a)

Through dripping particles

b)

Through spinning

c)

By keeping large particle in the center and smaller on the outside

d)

By separating particles into different tubes

14.

If you were centrifuging whole milk, which would you expect to get flung further out from the center of the centrifuge?

a)

The skim milk

b)

The cream/fat

c)

Both would be equally flung

d)

Neither would be flung

15.

Which of the following scientist invented the centrifugal separator?

a)

Gustaf de Laval

b)

Donald ronholm

c)

Luis pastuer

d)

Rutherford

16.

The skimming efficiency of a separator consequently decreases with increased throughput.

a)

True

b)

False

17.

The centrifugation is based on the principle of when a force is less than the gravity desired.

a)

True

b)

False

18.

In 500 × g, what does g represent in accordance to centrifugation?

a)

Gravitational force

b)

Centrifugal force is 500 times greater than earthly gravitational force

c)

Centrifugal force is 500 times less than earthly gravitational force

d)

Centrifugal force is 500 times same as that of earthly gravitational force

19.

Which of the following is not a type of centrifugation?

a)

Hydro cyclone

b)

Tubular centrifuge

c)

Microfiltration

d)

Disk stack separator

20.

By increasing the feed rate of the liquid in tubular centrifuge the performance is increased.

a)

True

b)

False

21.

At what speed do you centrifuge blood?

a)

2200-2500 RPM

b)

3000-3200 RPM

c)

1000-1500 RPM

d)

4000 RPM

22.

Which of the following centrifugation is used to separate certain organelles from whole cell?

a)

Rate-zonal centrifugation

b)

Normal centrifugation

c)

Differential centrifugation

d)

Isopycnic centrifugation

23.

What is rate-zonal centrifugation?

a)

Based on separation of particles by mass

b)

Based on separation of particles by density

c)

Based on separation of particles on solubility

d)

Based on separation of particles on size

24.

Differential centrifugation is based on the differences in ______ of biological particles of different ___________.

a)

Size, density.

b)

Sedimentation rate, sizes and density.

c)

Size, structure.

d)

Mass, size.

25.

Which of the following statements about the basic principle of sedimentation is False?

a)

The denser a biological structure is, the faster it sediments in a centrifugal field.

b)

The more massive a biological particle is, the slower it moves in a centrifugal field.

c)

The denser the buffer system is, the slower the particle will move in a centrifugal field.

d)

The greater the centrifugal force is, the faster the particle sediments.

26.

Which of the following is/are the application of analytical centrifugation?

i. the determination of the purity of macromolecules.

ii. the determination of the relative molecular masses of solutes in their native state.

iii. the examination of changes in the molecular mass of supramolecular complexes.

iv. the detection of conformational changes.

a)

i only.

b)

i and ii only.

c)

i, ii, and iii only.

d)

All of these.

27.

Which of the following is/are appropriate care and maintenance of centrifuges?

i. Proper balancing of centrifuge tubes.

ii. Avoid long time exposure of the rotors to alkaline solution and acidic buffers.

iii. Cleaning centrifuges and rotors with coarse brushes and then wash them with distilled or deionised water after every run.

iv. For overnight storage, the rotors are left upside down and then positioned in a safe and dry place.

a)

i, ii, iii only.

b)

ii, iii and iv only.

c)

i, ii, and iv only.

d)

All of these