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Good Laboratory Practises_18601917108

Total questions: 15

Worksheet time: 8mins

Name
Class
Date
1.

In early 70's in USA, FDA had decided to check over____________ toxicology labs in depth.

a)

40

b)

41

c)

39

d)

38

2.

Good Laboratory Practices is an official regulation that was created by the FDA in which year?

a)

1977

b)

1978

c)

1975

d)

1976

3.

The GLP regulations that are accepted as international standards for non-clinical laboratory studies published by the US Food and Drug Administration in (a)   supplied the basis for the work of the Expert Group of FDA.

4.

what is the full form of OECD?

a)

Organization for Economic Co-operation and Development

b)

Organization for Eminent Co-operation and Development

c)

Organization for Economic Co-operation Department

d)

Organization for Economic Corporate Department

5.

The Environmental Health and Safety Division publishes free-off charge documents in-

a)

Testing and Assessment

b)

Principles on Good Laboratory Practice and Compliance Monitoring

c)

Pesticides and Risk Management

d)

Chemical Accidents and Harmonization of Regulatory Oversight in Biotechnology

6.

the Principles of Good Laboratory Practice (GLP) have been developed to promote the quality and validity of test data used for determining the safety of chemicals

and chemical products.

a)

true

b)

false

7.

A quality system related with the organizational process and the conditions under which non-clinical health and

environmental safety studies are planned, performed, monitored, recorded, archived and reported is known as-

(a)  

8.

what are the following principles of Good Laboratory Practices?

a)

to support the development of quality and validity of test data used for determining the safety of chemicals and chemicals

product

b)

to decrease the occurrence of mistakes or mix-ups through large and specific labeling requirements.

c)

to place a high degree of reliance upon creating and following a per-defined study plan.

d)

all of the above

9.

GLP includes which of the following points?

a)

Test facility management

b)

Quality assurance programme

c)

Meeting the requirements of the test facility

d)

Receipt, handling, sampling and storage

10.

(a)   means the persons, premises and operational units that are necessary for conducting the non-clinical health and environmental safety study.

11.

which of the following requirement of Test Facility?

a)

should be of appropriate size, construction and location to meet the requirements of the study.

b)

should be designed safe enough to get the validation results

confidently.

12.

The GLP Principles are designed to avoid the factors that would endanger the reconstructability of a study, by giving the only and final responsibility for the GLP

compliant conduct of a study to one single person, the Study Director. For each nonclinical laboratory study, a scientist or other professional of appropriate education, training, and experience should be identified as the study director.

a)

true

b)

false

13.

The (a)   has to be aware of all possible circumstances that might affect the quality and integrity of a study.

14.

The GLP Compliance Statement signed by the Study Director in the final study report.

a)

false

b)

true

15.

(a)   is the process, procedures and authority used to accept or reject all components, drug product containers, closures, in-process materials, packaging material, labeling and drug products and the authority to review production records to assure that no errors have occurred, that they have been fully investigated. The quality and reliability of test data count on the state and condition of the test system which is used in its production.