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WorksheetsFluorescence
Total questions: 25
Worksheet time: 5mins
CD4 cells are generally restricted by
CD-1
MHC-1
MHC-2
Beta-2 Microglobulin
Successful immunisation can be impared by
Maternal Antibodies
Adjuvants
Cytokines
Cloning the vaccine
The classical pathway of complement is primarily activated by:
Microsomal surface
Antibodies
Cytokines
Interleukins
Pattern recognition structures present in cytoplasm of host cells include:
TLR-4
DC-SIGN and Dectin-1
NOD 1/2 and RIG like receptor
TLR-9
Defects in the production room of, or response to Interferon Gamma primarily results in:
Increased susceptibility to intracellular pathogens like mycobacteria
Increased susceptibility to viruses
Autoimmunity
Neutropenia
The lymphocytes antigen receptor Repertoire is mostly generated:
In the periphery following exposure to antigens
Following vaccination
By cutting or splicing V, D or J gene segments
Mutation of tcr and immunoglobulin
Macrophage activation to kill intracellular pathogens is primarily mediated by:
IL-2
IFN- gamma
IL-17
GM-CSF
Cytokines primarily involved in T cell proliferation and development are
IL-2 and IL-5
IL-12 and IL-7
IL-2 and IL-7
IL-4 and IL-5
Granulomas formed in response to infection are:
Enriched in neutrophils
Enriched in activated T cells and macrophages
Mostly produced in response to viral infections
Mostly produced in response to encapsulated bacteria
Adhesion molecules can control leukocyte migration by
Binding to specific antigen
Changing lymphocyte survival
Binding to ligands on vascular endothelium
Agglutinating pathogens in the tissue
Out of various antinuclear antibodies, pathognomonic of SLE is:
Antibody to single-stranded DNA
Antibody to double-stranded DNA
Antibody to histones
Antibody to nucleolar antigen
In cases of renal failure on long-term haemodialysis, there is development of following type of amyloid:
Amyloid light chain (AL)
Amyloid-associated protein (AA)
B amyloid protein (Ab)
Amyloid b2 microglobulin (Ab2m)
Chediak Higashi syndrome is an immunodeficiency disease which occurs due to
T cell Defect
B cell Defect
Both T and B cell Defect
Diminished phagocytic activity
Opsonin Index is calculated by
Incubating fresh citrated blood with bacterial suspension at 37°C for 10 mins.
Incubating fresh salined blood with bacterial suspension at 37°C for 10 mins.
Incubating fresh citrated blood with bacterial suspension at 37°C for 15 mins.
Incubating fresh citrated blood without bacterial suspension at 37°C for 15 mins.
Select the correct option for the given statements for the Standard dose-response in RadioImmunoAssay.
St.A:- Is also Called Calibrating Curve
St.B:- Is done by running reaction with fixed amounts of antibody and antigen
St.C:- Is given by the ratio of bound Antigen to total antigen.
A
B,C
A,B,C
A,C
Identify the pointed microscopic Structure
Lipofuscin Granules
Lysosome
Phagolysosome
Secondary Lysosome
Immunofluorescence staining from a kidney biopsy from a 35 year old patient presenting with proteinuria has been shown. What is the most probable cause?
RPGN
PSGN
Lupus Nephropathy
Good Pasteur Syndrome
A 12 year old boy had a cut in his arm 4 days ago. Now the bleeding has been stopped due to granulation tissue formation. While taking skin biopsy, a part of this tissue was also taken in. The histology is been shown here. What type of collagen tissue will be present here?
Type-1
Type-2
Type-3
Type-4
A worker was working in a factory from the past 20 years, and now presented with pleural thickening and fibrosis. Histopathology is shown. What is the probable diagnosis?
Asbestosis
Cotton fibre
Coal worker Pnemoconiasis
Silicosis
Storage temperature of RBC, Platelet, Fresh Frozen Plasma(FFP) are:
2-6°C, 20-22°C, 30°C
20-26°C, 20-22°C, 30°C
2-6°C, 20-22°C, 3-10°C
2-6°C, 20-32°C, 30°C
Abnormality in elastin can lead to all of the following, except-
Fractures
Aortic aneurysm
Joint Laxity
Subluxation of Lens
Which of the following is true about Blood transfusion and Packed RBCs?
Should be started within 4 hours after receiving from Blood Bank
Should be completed within 4 hours after receiving from Blood Bank
Wait till the patient is stable and then transfuse irrespective of time gap.
Should be completed within 6 hours after receiving from Blood Bank
Which do the following can not be diagnosed without positive ANA?
SLE
Sjogrens Syndrome
Drug Induced Lupus
Scleroderma
Which of the following is not true regarding NETosis?
Causes death of Neutrophils
Chromatin Condensation
Detected in blood of septic patients
Involved in SLE
The Nobel prize of 2018 in Medicine/Physiology was awarded for the discovery of-
Crispr-Cas 9
Negative Immune Regulation
Circadian rhythm
Apoptotic Pathway
