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Worksheetspharmacy HAAD EXAM 2019
Total questions: 100
Worksheet time: 2hrs 40mins
All of the following are non-competitive acetyl cholinesterase inhibitors, except
Donepezil
Rivastigmine
Galantamine (reversible and competitive ache inhibitor)
Tacrine
Mepredine not suitable for long time because???
cardiotoxicity
neurotoxicity (elderly)
nephrotoxicity
case about patient recently widowed, is suffering from severe depression, is taking imipramine(TCA) block the reuptake of :
dopamine
serotonin and norepinephrine
norepinephrine
serotonin
4. same case about the widow TCA metabolized by:
alcohol dehydrogenase
amine hydroxlase
CYP 450
5. Same case about the widow TCA block all of the following receptors except:
Histaminic receptors
Alpha adrenergic receptors
Beta adrenergic receptors
6. Same case about the widow:
TCA used in all of the following except:
Panic disorders
Schizophrenia
Migraine
Neuropathic pain
7. Metabolic effects of BB include all of the following except:
Decreased glucagon release
Decreased glycogenolysis
Hypertriglyceridemia
Hyperglycemia
Least effect for BB in :
Benign prostatic hyperplasia
Myocardial infarction
Arrhythmia
Angina pectoris
All of the following decrease the effects of BB except:
1- Phenytoin
Phenobarbital
rifampicin
Fluoxetine (increase effect of BB)
Female patients suffering from absence seizures, which of the following is not indicated:
Ethosuximide
Lamotrigine
Diazepam
Carbamazepine
we are using all to treat absence seizure except:
phenytoin
valproic acid
ethosuximide
lamotrigine
What is the drug of choice for status epilepticus :
Phenytoin
Carbamazepine
Lamotrigine
Valproate
All of the following anti-epileptic drugs are avoided in pregnancy except:
Phenytoin
Valproate
Diazepam
clonazepam
Doctor wants to discontinue anti-epileptic drug for female patient, which of the following guarantees low recurrence:
EEG
History of frequent seizures
Onset in childhood
MRI
Patients develop tolerance against all of the following effects of morphine except:
Respiratory depression
Euphoria
Analgesia
Pinpoint pupil (miosis)
All used for Morphine dependence except :
a. Methadone
Codeine
Clonidine
Buprenorphine
Case about patient suffering from severe skeletal muscle rigidity and is diagnosed with myasthenia gravis, which of the following is NOT true:
Diagnosed by edrophonium
Glucocorticoids are not useful in this condition
Autoimmune disease caused by antibodies against ACH receptors at motor endplate
All of the following are used for treatment of acute mania except:
Valproate
Lorazepam
Chlorpromazine
Lithium
Which drug is not used in parkinson’s disease
Chlorthalidone
Bromocriptine
Amantadine
Rasagiline
Long case about Parkinson patient: What is the effect of carbidopa on levodopa:
Decrease its metabolism in the CNS
Decrease its peripheral decarboxylation to dopamine
What are the symptoms of parkinson
Tremors and agitation
Inability to initiate voluntary movements
Abnormal posture and gait
all
Which of the following vitamins decreases the effects of levodopa when taken concomitantly
Vit B6 puridoxine
Vit B12
Vit B1
Vit B5
The decrease in the effect of levodopa occurs within
After 5 years
After 3 years
After 2 years
From the 3rd to the 5th year
Pilocarpine is used in all of the following except
In narrow angle glaucoma
Alternatively with mydriatics to separate the iris
In closed angle glaucoma
Standard one for open glaucoma
phenytoin side effect ,all except
gingival hyperplasia
nystagmus
nephrotoxicity
Regarding Fluxetine
half life is 50 hrs
have a metabolite as active as the parentdrug
used in bulimia nervosa
undergo first pass effect
all
Which of the following used to make mydriasis in checking refractive errors?
Atropine
Tropicamide
case scenario about female patient have GOUT was weak & dizzy & fatigue and another problems like she can’t raise her hand and having some blood disorders like agrnaulocytosis and leucopenia and type of anemia which anti gout are probably to cause this Side effects
allopurinol
colchicine
the qs about pharyngitis, the patient was penicillin allergic but the organism is penicillin sensitive
Penicillin
Cephalosporin
Azithromycin
Tetracycline
Which one of tetracyclines is suitable for renal failure pt ( it was in a case ) :
Doxycycline
Minocycline
Tetracycline
which of the following is not fungus:-
mushroom
E.coli
mitochondrial toxicity,, ANTIVIRAL used:
lamivudine
amatidine
zidovudine
mitochondrial toxicity,, ANTIVIRAL used:
lamivudine
amatidine
zidovudine
antiviral used for influenza and , Parkinson: ( came twice )
amantidine
lamuvidine
zidovudine
In AIDS the CD4 less than:-
200
400
500
600
CD4 bind to which antigen in the HIV positive Pt:-
T lymphocyte
B lymphocyte
Which is not true about immune reconstitution inflammatory syndrom :
corticosteroids and anti - inflammatory drugs don’t shorten inflammation action
The action of antiviral start when virus load is high
The pt start respond to treatment when CD4 is high
charcoal act by which :-
adsorbant
absorbant
SIADH(Syndrome of inappropriate antidiuretic hormone) cause all of the following except:-
hyponatremia
hypernatremia
water excess
Inadequate vasopressin production
MTC means
Maximum toxic conc.
Maximum safe conc
10 ml ampoule of 3% drug how many ml required to give 150mg dose?
3ml
5ml
7ml
9ml
Dose for patient is 75mg, how ml needed from 125mg/5ml solution :
5 ml
3 ml
15 ml
Advantages of IV route over oral route:
safe and convenient, rapid onset, dose can be titrated, can be used in ER
safe and convenient, can be used in ER
rapid onset, dose can be titrated, can be used in ER
rapid onset, can be used in ER
Foam in pharmacy found as spray is used as:
Burn dressing and topical but not for rectal administration
Topical and rectal but not for burns
Topical, rectal and for burn dressing
Topical only
which is true about dry gum emulsion:-
ratio 4:2:1
water gum and oil are added together and triturated slowly
oil and gum are triturated and water added slowly.
Conductivity in emulsion, the dispersed phase for such emulsion is:
Aqueous
Non aqueous
Aqueous and non aqueous
velocity in dispersed phase affected by:-
particle size
particle homogeneity
elecrtic charge
all
Conductivity test – Dilution test – Dye test used for which dosage form :
Susp
Emulsion
Foam
Gel
Particle size affects:
Suspend ability
Penetrability
Dissolution rate
Dose to dose uniformity
all of above
Xanaxآ® alprazolam (CDA) must store in:
Steel cupboard well closed
Cupboard opened by 2 person
70 yr old diabetic pt on oral hypoglycemica and suffering from hypertension ; Which of the following antihypertensive drugs is not recommended :
losartan
enalapril
Hydrochlorothiazide
Atenolol
patient with hypertension put on antihypertensive drug, after few months developed heart failure manifested as reduction in heart rate and contraction, which antihypertensive drug patient put on:
Lisinopril
verpamil
prozosin
Thiazide diuretic
timolol is contraindicated in all the following except
HTN
Congestive Heart failure
Bronchial asthma
prinzmetal angina:
sudden spasm
sudden spasm with atherosclerosis
sudden spasm with atherosclerosis and not responsive to CCBs and nitroglycerin
sudden spasm ,with atherosclerosis, and respond to CCBs and nitroglycerin
which of the following not used in prinzmetal angina??
atenolol
nifedipine
nitroglycerin
dilitazem
years old Male patient , he is a smoker and he is taking an antiarrhythmic medications , which of the following drugs should be avoided :
Digoxin
Verapamil
Amiodrone
lidocaine
what is not true about Arrhythmia ( statements ) :
most cause of recurrent arrhythmia due to reentry
Most Of them is Calcium and sodium blocker
SA node is the pace maker ( something like that )
anti-arrythmic safer than operation
Patient with arrhythmia given medication that decrease the velocity and force of contractility which one of this drugs :
Verapamil
enalapril
Mechanism of action of digitalis all true except:
increase contractility
decrease vascular resistance
have modify effect on autonomic nervous system
maintain ventricular rate in atrial fibrillation
Case Patient with glaucoma and blood pressure 220/110 and hypertensive crisis and ask which to avoid :-
nicardipine
fenoldopam
Na nitroprusside
labetalol
patient diagnosed with Hyperlipidemia and decreased HDL , what is the drug useful in his condition ?
Niacin
Clofibrate
Cholestyramine
Rousavastatin
Thiazide diuretic doesn’t cause
hypokalemia
hypocalcemia
Hyponatremia
The role of B-blocker in MI is all of the following except:
Decrease mortality and morbidity
decrease infract size
Increase O2 demand
The dry cough in ACE inhibitors: EXCEPT:
Accumulation of bradykinin
In women more than men
Appears in 6 months
Dose related
Primaquine is contraindicated in all of the following except:
SLE,RA
G6PD deficiency
Lactating female
Pregnancy
16- All of the following cause constipation except
Bisacodyl
Morphine
Calcium
ACEI
When giving ethambutol (for treatingTB) for a long duration, continuous follow-up/check-up is necessary because of this condition:
Renal failure
Liver dysfunction
vision problem
24-What’s the type of study that’s MOST reliable?
Cohort randomized
Case study
Case report
Case scenario
25- What’s the type of study that’s LEAST reliable?
Cohort randomized
Case study
Case report
Case scenario
28-patient with panic attack what is DOC
buspirone
benzodiazepine
antidepressant
barbiturate
A Kid took peanut butter and he’s allergic to peanut; he developed rashes and urticarial. What type of allergic reaction is this? Allergy to food
Type 1
Type 2
Type 3
Type 4
Not a side effect of (ACEIs) ramipril:
Hypokalemia
Low level of potassium
angioedema
hyperkalemia
dry cough
which of the following no need for antibiotic dose adjustment ?
hypercholesterolemia
elderly patient
renal disease patient
AIDS
@40- Patient with TB has discoloration in urine (reddish color) on which medication?
Rifampicin
Ethambutol
Isoniazid
Pyrama
Which of the following S.E of B2 agonist (bronchodilation) that most people=more common may have?
Hypokalemia
Hypomagnesia
Tremor
Etoposide cause DNA damage through inhibition:
Topoisomerase I
Topoisomerase II
Topoisomerase III
Topoisomerase IIII
prostaglandin that can be used for glaucoma and eyelash Hypotrichosis
Lantoprost
Travoprost
bimatoprost
tafluprost
smoker with COPD , what is the drug of choice ?
Busonide
Ipratopium
Theophyllin
Montelukast
A physician wants to switch a terminally-ill patient from slow release morphine sulphate tablets, 15 mg twice daily, to a liquid morphine sulphate dosage
form because the patient has difficulty in swallowing tablets. If a morphine sulphate solution containing 5 mg per mL is prescribed q4h, what volume should be dispensed for a 20 day supply to provide the same pain relief as the tablet regimen?
20 mL
60 mL
100 mL
120 Ml
Penetration through CSF )cerebrospinal fluid ( depends on all except:
Lipid soulibility
Water soulibility
Mwt
protein binding
Which of the following causes tachycardia:
B blocker
verapamil (CCB)
diltiazem (BZD)
isosorbide dinitrate
Not to be used in Chrons disease:
Adalimumab
Certolizumab
Etanercept
Another biological treatment
Which not used in heart failure:
Captopril
Digoxin
Nefidipine
Propranolol
which of the following drugs acts on T-lymphocyte blocking?
Adluximab
Etanercept
Alefacept
Which of the following no need for antibiotic dose adjustment:
hypercholesterolemia
elderly patient
renal disease patient
AIDS
The metabolic effect of combining glucocorticoid and tacrolimus is:
Hypocalcemia
Hyperlipidemia
Hyperglycemia
Hyponatremia
Which antiplatelet cause blood disorder (agranulocytosis, thrombocytopenia) and a type of anemia) aplastic anemia:
Ticlopedine
Clopidogril
Aspirin
Abciximab
Which part in aerosol press on valve:
Actuator
House
Dip tube
negative symptoms apathy and blunted are benefited with:
Respiridone
Haloperidol
fluphenazine
chloropromazine
Aspirin overdose symptoms are all of the following except:
Hypothermia
Metabolic acidosis
Respiratory depression
patient on cyclophosphamid has developed hematuria due to release of which :
phosphoramide mustard
Acrolein
Mensa
Which of the following S.E of B2 agonist (bronchodilation) that most people=more common may have?
Hypokalemia
Hypomagnesia
Tremor
Etoposide cause DNA damage through inhibition:
Topoisomerase I
Topoisomerase II
Topoisomerase III
Topoisomerase IIII
prostaglandin that can be used for glaucoma and eyelash Hypotrichosis
Lantoprost
Travoprost
bimatoprost
tafluprost
smoker with COPD , what is the drug of choice ?
Busonide
Ipratopium
Theophyllin
Montelukast
Penetration through CSF ) cerebrospinal fluid ( depends on all except:
Lipid soulibility
Water soulibility
Mwt
protein binding
all used in motion sickness except:
Cinnarazine
Hyoscine (scopinal)
Scopolamine “anti-muscarnic
propamide
Which not used in heart failure:
Captopril
Digoxin
Nefidipine*
Propranolol*
The metabolic effect of combining glucocorticoid and tacrolimus is:
Hypocalcemia
Hyperglycemia
Hyperlipidemia
Hyponatremia
Which antiplatelet cause blood disorder (agranulocytosis, thrombocytopenia) and a type of anemia) aplastic anemia:
Ticlopedine
Clopidogril
Aspirin
Abciximab
