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pharmacy HAAD EXAM 2019

Total questions: 100

Worksheet time: 2hrs 40mins

Name
Class
Date
1.

All of the following are non-competitive acetyl cholinesterase inhibitors, except

a)

Donepezil

b)

Rivastigmine

c)

Galantamine (reversible and competitive ache inhibitor)

d)

Tacrine

2.

Mepredine not suitable for long time because???

a)

cardiotoxicity

b)

neurotoxicity (elderly)

c)

nephrotoxicity

3.

case about patient recently widowed, is suffering from severe depression, is taking imipramine(TCA) block the reuptake of :

a)

dopamine

b)

serotonin and norepinephrine

c)

norepinephrine

d)

serotonin

4.

4. same case about the widow TCA metabolized by:

a)

alcohol dehydrogenase

b)

amine hydroxlase

c)

CYP 450

5.

5. Same case about the widow TCA block all of the following receptors except:

a)

Histaminic receptors

b)

Alpha adrenergic receptors

c)

Beta adrenergic receptors

6.

6. Same case about the widow:

TCA used in all of the following except:

a)

Panic disorders

b)

Schizophrenia

c)

Migraine

d)

Neuropathic pain

7.

7. Metabolic effects of BB include all of the following except:

a)

Decreased glucagon release

b)

Decreased glycogenolysis

c)

Hypertriglyceridemia

d)

Hyperglycemia

8.

Least effect for BB in :

a)

Benign prostatic hyperplasia

b)

Myocardial infarction

c)

Arrhythmia

d)

Angina pectoris

9.

All of the following decrease the effects of BB except:

a)

1- Phenytoin

b)

Phenobarbital

c)

rifampicin

d)

Fluoxetine (increase effect of BB)

10.

Female patients suffering from absence seizures, which of the following is not indicated:

a)

Ethosuximide

b)

Lamotrigine

c)

Diazepam

d)

Carbamazepine

11.

we are using all to treat absence seizure except:

a)

phenytoin

b)

valproic acid

c)

ethosuximide

d)

lamotrigine

12.

What is the drug of choice for status epilepticus :

a)

Phenytoin

b)

Carbamazepine

c)

Lamotrigine

d)

Valproate

13.

All of the following anti-epileptic drugs are avoided in pregnancy except:

a)

Phenytoin

b)

Valproate

c)

Diazepam

d)

clonazepam

14.

Doctor wants to discontinue anti-epileptic drug for female patient, which of the following guarantees low recurrence:

a)

EEG

b)

History of frequent seizures

c)

Onset in childhood

d)

MRI

15.

Patients develop tolerance against all of the following effects of morphine except:

a)

Respiratory depression

b)

Euphoria

c)

Analgesia

d)

Pinpoint pupil (miosis)

16.

All used for Morphine dependence except :

a)

a. Methadone

b)

Codeine

c)

Clonidine

d)

Buprenorphine

17.

Case about patient suffering from severe skeletal muscle rigidity and is diagnosed with myasthenia gravis, which of the following is NOT true:

a)

Diagnosed by edrophonium

b)

Glucocorticoids are not useful in this condition

c)

Autoimmune disease caused by antibodies against ACH receptors at motor endplate

18.

All of the following are used for treatment of acute mania except:

a)

Valproate

b)

Lorazepam

c)

Chlorpromazine

d)

Lithium

19.

Which drug is not used in parkinson’s disease

a)

Chlorthalidone

b)

Bromocriptine

c)

Amantadine

d)

Rasagiline

20.

Long case about Parkinson patient: What is the effect of carbidopa on levodopa:

a)

Decrease its metabolism in the CNS

b)

Decrease its peripheral decarboxylation to dopamine

21.

What are the symptoms of parkinson

a)

Tremors and agitation

b)

Inability to initiate voluntary movements

c)

Abnormal posture and gait

d)

all

22.

Which of the following vitamins decreases the effects of levodopa when taken concomitantly

a)

Vit B6 puridoxine

b)

Vit B12

c)

Vit B1

d)

Vit B5

23.

The decrease in the effect of levodopa occurs within

a)

After 5 years

b)

After 3 years

c)

After 2 years

d)

From the 3rd to the 5th year

24.

Pilocarpine is used in all of the following except

a)

In narrow angle glaucoma

b)

Alternatively with mydriatics to separate the iris

c)

In closed angle glaucoma

d)

Standard one for open glaucoma

25.

phenytoin side effect ,all except

a)

gingival hyperplasia

b)

nystagmus

c)

nephrotoxicity

26.

Regarding Fluxetine

a)

half life is 50 hrs

b)

have a metabolite as active as the parentdrug

c)

used in bulimia nervosa

d)

undergo first pass effect

e)

all

27.

Which of the following used to make mydriasis in checking refractive errors?

a)

Atropine

b)

Tropicamide

28.

case scenario about female patient have GOUT was weak & dizzy & fatigue and another problems like she can’t raise her hand and having some blood disorders like agrnaulocytosis and leucopenia and type of anemia which anti gout are probably to cause this Side effects

a)

allopurinol

b)

colchicine

29.

the qs about pharyngitis, the patient was penicillin allergic but the organism is penicillin sensitive

a)

Penicillin

b)

Cephalosporin

c)

Azithromycin

d)

Tetracycline

30.

Which one of tetracyclines is suitable for renal failure pt ( it was in a case ) :

a)

Doxycycline

b)

Minocycline

c)

Tetracycline

31.

which of the following is not fungus:-

a)

mushroom

b)

E.coli

32.

mitochondrial toxicity,, ANTIVIRAL used:

a)

lamivudine

b)

amatidine

c)

zidovudine

33.

mitochondrial toxicity,, ANTIVIRAL used:

a)

lamivudine

b)

amatidine

c)

zidovudine

34.

antiviral used for influenza and , Parkinson: ( came twice )

a)

amantidine

b)

lamuvidine

c)

zidovudine

35.

In AIDS the CD4 less than:-

a)

200

b)

400

c)

500

d)

600

36.

CD4 bind to which antigen in the HIV positive Pt:-

a)

T lymphocyte

b)

B lymphocyte

37.

Which is not true about immune reconstitution inflammatory syndrom :

a)

corticosteroids and anti - inflammatory drugs don’t shorten inflammation action

b)

The action of antiviral start when virus load is high

c)

The pt start respond to treatment when CD4 is high

38.

charcoal act by which :-

a)

adsorbant

b)

absorbant

39.

SIADH(Syndrome of inappropriate antidiuretic hormone) cause all of the following except:-

a)

hyponatremia

b)

hypernatremia

c)

water excess

d)

Inadequate vasopressin production

40.

MTC means

a)

Maximum toxic conc.

b)

Maximum safe conc

41.

10 ml ampoule of 3% drug how many ml required to give 150mg dose?

a)

3ml

b)

5ml

c)

7ml

d)

9ml

42.

Dose for patient is 75mg, how ml needed from 125mg/5ml solution :

a)

5 ml

b)

3 ml

c)

15 ml

43.

Advantages of IV route over oral route:

a)

safe and convenient, rapid onset, dose can be titrated, can be used in ER

b)

safe and convenient, can be used in ER

c)

rapid onset, dose can be titrated, can be used in ER

d)

rapid onset, can be used in ER

44.

Foam in pharmacy found as spray is used as:

a)

Burn dressing and topical but not for rectal administration

b)

Topical and rectal but not for burns

c)

Topical, rectal and for burn dressing

d)

Topical only

45.

which is true about dry gum emulsion:-

a)

ratio 4:2:1

b)

water gum and oil are added together and triturated slowly

c)

oil and gum are triturated and water added slowly.

46.

Conductivity in emulsion, the dispersed phase for such emulsion is:

a)

Aqueous

b)

Non aqueous

c)

Aqueous and non aqueous

47.

velocity in dispersed phase affected by:-

a)

particle size

b)

particle homogeneity

c)

elecrtic charge

d)

all

48.

Conductivity test – Dilution test – Dye test used for which dosage form :

a)

Susp

b)

Emulsion

c)

Foam

d)

Gel

49.

Particle size affects:

a)

Suspend ability

b)

Penetrability

c)

Dissolution rate

d)

Dose to dose uniformity

e)

all of above

50.

Xanaxآ® alprazolam (CDA) must store in:

a)

Steel cupboard well closed

b)

Cupboard opened by 2 person

51.

70 yr old diabetic pt on oral hypoglycemica and suffering from hypertension ; Which of the following antihypertensive drugs is not recommended :

a)

losartan

b)

enalapril

c)

Hydrochlorothiazide

d)

Atenolol

52.

patient with hypertension put on antihypertensive drug, after few months developed heart failure manifested as reduction in heart rate and contraction, which antihypertensive drug patient put on:

a)

Lisinopril

b)

verpamil

c)

prozosin

d)

Thiazide diuretic

53.

timolol is contraindicated in all the following except

a)

HTN

b)

Congestive Heart failure

c)

Bronchial asthma

54.

prinzmetal angina:

a)

sudden spasm

b)

sudden spasm with atherosclerosis

c)

sudden spasm with atherosclerosis and not responsive to CCBs and nitroglycerin

d)

sudden spasm ,with atherosclerosis, and respond to CCBs and nitroglycerin

55.

which of the following not used in prinzmetal angina??

a)

atenolol

b)

nifedipine

c)

nitroglycerin

d)

dilitazem

56.

years old Male patient , he is a smoker and he is taking an antiarrhythmic medications , which of the following drugs should be avoided :

a)

Digoxin

b)

Verapamil

c)

Amiodrone

d)

lidocaine

57.

what is not true about Arrhythmia ( statements ) :

a)

most cause of recurrent arrhythmia due to reentry

b)

Most Of them is Calcium and sodium blocker

c)

SA node is the pace maker ( something like that )

d)

anti-arrythmic safer than operation

58.

Patient with arrhythmia given medication that decrease the velocity and force of contractility which one of this drugs :

a)

Verapamil

b)

enalapril

59.

Mechanism of action of digitalis all true except:

a)

increase contractility

b)

decrease vascular resistance

c)

have modify effect on autonomic nervous system

d)

maintain ventricular rate in atrial fibrillation

60.

Case Patient with glaucoma and blood pressure 220/110 and hypertensive crisis and ask which to avoid :-

a)

nicardipine

b)

fenoldopam

c)

Na nitroprusside

d)

labetalol

61.

patient diagnosed with Hyperlipidemia and decreased HDL , what is the drug useful in his condition ?

a)

Niacin

b)

Clofibrate

c)

Cholestyramine

d)

Rousavastatin

62.

Thiazide diuretic doesn’t cause

a)

hypokalemia

b)

hypocalcemia

c)

Hyponatremia

63.

The role of B-blocker in MI is all of the following except:

a)

Decrease mortality and morbidity

b)

decrease infract size

c)

Increase O2 demand

64.

The dry cough in ACE inhibitors: EXCEPT:

a)

Accumulation of bradykinin

b)

In women more than men

c)

Appears in 6 months

d)

Dose related

65.

Primaquine is contraindicated in all of the following except:

a)

SLE,RA

b)

G6PD deficiency

c)

Lactating female

d)

Pregnancy

66.

16- All of the following cause constipation except

a)

Bisacodyl

b)

Morphine

c)

Calcium

d)

ACEI

67.

When giving ethambutol (for treatingTB) for a long duration, continuous follow-up/check-up is necessary because of this condition:

a)

Renal failure

b)

Liver dysfunction

c)

vision problem

68.

24-What’s the type of study that’s MOST reliable?

a)

Cohort randomized

b)

Case study

c)

Case report

d)

Case scenario

69.

25- What’s the type of study that’s LEAST reliable?

a)

Cohort randomized

b)

Case study

c)

Case report

d)

Case scenario

70.

28-patient with panic attack what is DOC

a)

buspirone

b)

benzodiazepine

c)

antidepressant

d)

barbiturate

71.

A Kid took peanut butter and he’s allergic to peanut; he developed rashes and urticarial. What type of allergic reaction is this? Allergy to food

a)

Type 1

b)

Type 2

c)

Type 3

d)

Type 4

72.

Not a side effect of (ACEIs) ramipril:

a)

Hypokalemia

b)

Low level of potassium

c)

angioedema

d)

hyperkalemia

e)

dry cough

73.

which of the following no need for antibiotic dose adjustment ?

a)

hypercholesterolemia

b)

elderly patient

c)

renal disease patient

d)

AIDS

74.

@40- Patient with TB has discoloration in urine (reddish color) on which medication?

a)

Rifampicin

b)

Ethambutol

c)

Isoniazid

d)

Pyrama

75.

Which of the following S.E of B2 agonist (bronchodilation) that most people=more common may have?

a)

Hypokalemia

b)

Hypomagnesia

c)

Tremor

76.

Etoposide cause DNA damage through inhibition:

a)

Topoisomerase I

b)

Topoisomerase II

c)

Topoisomerase III

d)

Topoisomerase IIII

77.

prostaglandin that can be used for glaucoma and eyelash Hypotrichosis

a)

Lantoprost

b)

Travoprost

c)

bimatoprost

d)

tafluprost

78.

smoker with COPD , what is the drug of choice ?

a)

Busonide

b)

Ipratopium

c)

Theophyllin

d)

Montelukast

79.

A physician wants to switch a terminally-ill patient from slow release morphine sulphate tablets, 15 mg twice daily, to a liquid morphine sulphate dosage

form because the patient has difficulty in swallowing tablets. If a morphine sulphate solution containing 5 mg per mL is prescribed q4h, what volume should be dispensed for a 20 day supply to provide the same pain relief as the tablet regimen?

a)

20 mL

b)

60 mL

c)

100 mL

d)

120 Ml

80.

Penetration through CSF )cerebrospinal fluid ( depends on all except:

a)

Lipid soulibility

b)

Water soulibility

c)

Mwt

d)

protein binding

81.

Which of the following causes tachycardia:

a)

B blocker

b)

verapamil (CCB)

c)

diltiazem (BZD)

d)

isosorbide dinitrate

82.

Not to be used in Chrons disease:

a)

Adalimumab

b)

Certolizumab

c)

Etanercept

d)

Another biological treatment

83.

Which not used in heart failure:

a)

Captopril

b)

Digoxin

c)

Nefidipine

d)

Propranolol

84.

which of the following drugs acts on T-lymphocyte blocking?

a)

Adluximab

b)

Etanercept

c)

Alefacept

85.

Which of the following no need for antibiotic dose adjustment:

a)

hypercholesterolemia

b)

elderly patient

c)

renal disease patient

d)

AIDS

86.

The metabolic effect of combining glucocorticoid and tacrolimus is:

a)

Hypocalcemia

b)

Hyperlipidemia

c)

Hyperglycemia

d)

Hyponatremia

87.

Which antiplatelet cause blood disorder (agranulocytosis, thrombocytopenia) and a type of anemia) aplastic anemia:

a)

Ticlopedine

b)

Clopidogril

c)

Aspirin

d)

Abciximab

88.

Which part in aerosol press on valve:

a)

Actuator

b)

House

c)

Dip tube

89.

negative symptoms apathy and blunted are benefited with:

a)

Respiridone

b)

Haloperidol

c)

fluphenazine

d)

chloropromazine

90.

Aspirin overdose symptoms are all of the following except:

a)

Hypothermia

b)

Metabolic acidosis

c)

Respiratory depression

91.

patient on cyclophosphamid has developed hematuria due to release of which :

a)

phosphoramide mustard

b)

Acrolein

c)

Mensa

92.

Which of the following S.E of B2 agonist (bronchodilation) that most people=more common may have?

a)

Hypokalemia

b)

Hypomagnesia

c)

Tremor

93.

Etoposide cause DNA damage through inhibition:

a)

Topoisomerase I

b)

Topoisomerase II

c)

Topoisomerase III

d)

Topoisomerase IIII

94.

prostaglandin that can be used for glaucoma and eyelash Hypotrichosis

a)

Lantoprost

b)

Travoprost

c)

bimatoprost

d)

tafluprost

95.

smoker with COPD , what is the drug of choice ?

a)

Busonide

b)

Ipratopium

c)

Theophyllin

d)

Montelukast

96.

Penetration through CSF ) cerebrospinal fluid ( depends on all except:

a)

Lipid soulibility

b)

Water soulibility

c)

Mwt

d)

protein binding

97.

all used in motion sickness except:

a)

Cinnarazine

b)

Hyoscine (scopinal)

c)

Scopolamine “anti-muscarnic

d)

propamide

98.

Which not used in heart failure:

a)

Captopril

b)

Digoxin

c)

Nefidipine*

d)

Propranolol*

99.

The metabolic effect of combining glucocorticoid and tacrolimus is:

a)

Hypocalcemia

b)

Hyperglycemia

c)

Hyperlipidemia

d)

Hyponatremia

100.

Which antiplatelet cause blood disorder (agranulocytosis, thrombocytopenia) and a type of anemia) aplastic anemia:

a)

Ticlopedine

b)

Clopidogril

c)

Aspirin

d)

Abciximab