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DNA Structure and Replication Review

Total questions: 35

Worksheet time: 20mins

Name
Class
Date
1.

The synthesis (S) phase is characterized by

a)

DNA replication

b)

cell division

c)

replication of the mitochondria and other organelles

d)

the division of the cytoplasm

2.

DNA Replication is called semi-conservative because

a)

The new strands are only made of new daughter cells

b)

The new strands contain both a parent and a daughter strand

c)

The parent strand completely disintegrates

d)

There are no new daughter strand

3.

The backbone of DNA is composed of

a)

sugars linked to phosphates

b)

organic bases

c)

hydrogen-bonded molecules

d)

links between bases and sugars

4.

Watson and Crick described the DNA molecule as a

a)

straight chain

b)

double helix molecule

c)

single-stranded molecule

d)

branching chain

5.

The two DNA strands that make up a double helix run in opposite directions to each other with the 5' end of one, right next to the 3' end of the other. The term used to describe this is called?

a)

semi conservative

b)

duplication

c)

parallel

d)

antiparallel

6.

Why are the new bases of the two DNA strands added in opposite directions during replication?

a)

The DNA polymerase can work only in one direction, 5' to 3'

b)

The bases are positively and negatively charged

c)

The new bases are not added in opposite directions

d)

It increases efficiency and prevents mutations

7.

All of the following are true about the structure of DNA except

a)

short strands of DNA are contained in chromosomes inside the nucleus of a cell.

b)

every DNA nucleotide contains a sugar, a phosphate group, and a nitrogen base.

c)

DNA consists of two strands of nucleotides joined by hydrogen bonds.

d)

the long strands of nucleotides are twisted into a double helix.

8.

The part of the molecule for which deoxyribonucleic acid is named is the

a)

phosphate group

b)

pentose sugar

c)

hydroxyl group

d)

none of the above

9.

Purines are pyrimidines are

a)

nitrogen bases found in amino acids

b)

able to replace phosphate groups from defective DNA

c)

names of specific types of DNA molecules

d)

classification groups for nitrogen bases.

10.

Of the four nitrogen bases in DNA, which two are purines and which two are pyrimidines?

a)

adenine—thymine; uracil—cytosine

b)

adenine—thymine; guanine—cytosine

c)

adenine—guanine; thymine—cytosine

d)

uracil—thymine; guanine—cytosine

11.

Pyrimidines have

a)

single ring structures

b)

double ring structures

c)

triple ring structure

d)

quadruple ring structures

12.

The leading strand is

a)

always made in the opposite direction of the overall replication process.

b)

made in pieces.

c)

always made in the same direction as the overall replication process.

d)

made after the lagging strand.

13.

During DNA replication, a complementary strand of DNA is made for each original DNA strand. Thus, if a portion of the original strand is CCTAGCT, ten the new strand will be

a)

TTGCATG

b)

AAGTATC

c)

CCTAGCT

d)

GGATCGA

14.

which of the following is not true about DNA replication?

a)

it must occur before a cell can divide.

b)

two complementary strands are duplicated.

c)

the double strand unwinds and unzips while it is being duplicated.

d)

the process is catalyzed by enzymes called DNA mutagens.

15.

The enzyme responsible for stabilizing and keeping the two DNA strands separate is

a)

replicase

b)

DNA polymerase

c)

helicase

d)

single strand binding protein

16.

the enzyme that unwinds/unzips the DNA is called

a)

double helixes

b)

DNA helicase

c)

DNA ligase

d)

Single Strand Binding Protein

17.

Primase

a)

keep DNA strands separated

b)

fuses the Okazaki fragments

c)

short RNA segment needed to start DNA replication

d)

produces the RNA primer

18.

RNA Primer

a)

produces the RNA primer

b)

keeps DNA strands separated

c)

is a short RNA segment needed to start DNA replication

d)

are replication fragments of the lagging strand

19.

Which of the following fuses fragments of the replicated DNA strand?

a)

Helicase

b)

RNA primer

c)

DNA ligase

d)

DNA polymerase

20.

Okazaki fragments

a)

are replication fragments of the lagging strand

b)

keep DNA strands separated

c)

are short RNA segments needed to start DNA replication

d)

add DNA nucleotides to exposed bases

21.

DNA replication

a)

occurs by the addition of nucleotides to the end of the DNA molecule

b)

uses each strand of DNA molecule as a template for the creation of a new strand

c)

produces two daughter DNA molecules that are complementary to each other

d)

results in the formation of four new DNA strands

22.

When one DNA molecule is copied to make two DNA molecules, the new DNA contains

a)

25% of the parent DNA

b)

50% of the parent DNA

c)

75% of the parent DNA

d)

none of the parent DNA

23.

Multiple origins of replication on the DNA molecule of eukaryotic cells serve to

a)

shorten the time necessary for DNA replication

b)

assure the correct orientation of the two strands in the newly growing double helix

c)

remove errors in DNA replication

d)

reduce the number of "bubbles" that occur in the DNA molecule during replication

24.

If adenine makes up 20% of the bases in a double helix, what percent of the bases are guanine? Remember the base pairing rule of DNA.

a)

60%

b)

40%

c)

20%

d)

30%

25.

After replication, ______.

a)

one new DNA double helix consists of two old strands and the other new DNA double helix consists of two new strands

b)

each new DNA double helix consists of two old strands

c)

each new DNA double helix consists of one old strand and one new strand

d)

each new DNA double helix consists of two new strands

26.

A replication fork is

a)

an area where the DNA separates into 2 strands and the new DNA synthesis occurs

b)

a molecular utensil needed to stab DNA nucleotides in order to bring them to their complementary base

c)

the point where a cell must decide to replicate its DNA

d)

a factory made of many enzymes that bind to DNA for replication

27.

Prokaryotic organisms have only 1 origin of replication because

a)

their genome is so big, that they only need one

b)

their genome is so small, that they only need one

c)

their enzymes work faster than eukaryotic enzymes

d)

their enzymes work slower than eukaryotic enzymes

28.

What is the structure labeled C

a)

The leading strand

b)

The lagging strand

29.

What is the structure labeled G

a)

DNA ligase

b)

Primase

c)

DNA Polymerase

d)

RNA Primers

30.

What is the structure labeled D

a)

DNA ligase

b)

Single Strand Binding Proteins

c)

Primase

d)

RNA Primer

31.
The scientists who created an accurate model of the DNA double helix and won a Nobel Prize for this discovery
a)
Watson & Crick
b)
Watson, Crick, and Wilkins
c)
Wilkins & Crick
d)
Watson, Crick, Wilkins, and Franklin
32.
Who was responsible for determining the structure of DNA?
a)
Watson and Crick
b)
Chargaff
c)
Rosalind Franklin
d)
All of the above
33.
Who is responsible for producing this image?
a)
Francis Crick
b)
James Watson
c)
Rosalind Franklin
d)
Watson and Crick
34.
Nitrogenous bases are joined by which type of bond?
a)
polar bonds
b)
ionic bonds
c)
covalent bonds
d)
hydrogen bonds
35.
Which of the following units are repeatedly joined together to form a strand of DNA?
a)
amino acids
b)
nucleotides
c)
fatty acids
d)
polysaccharides