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WorksheetsPatho- Exam 5- CNS and Disorders
Total questions: 77
Worksheet time: 43mins
The brain and spinal cord are the parts of which nervous system?
Central Nervous System
Peripheral Nervous System
Autonomic Nervous System
Somatic Nervous System
What are the functions of the organs in the CNS?
integration; command center
interprets incoming sensory information
issues outgoing instructions
serve as the communication lines among sensory organs, the brain and spinal cord, and glands or muscles
Which nervous system contains the spinal nerves and cranial nerves?
Central Nervous System
Peripheral Nervous System
Autonomic Nervous System
Somatic Nervous System
What are the functions of the PNS?
serve as communication lines among sensory organs, the brain and spinal cord, and glands or muscles
integration; command center
issues outgoing instructions
interprets incoming sensory information
Nerve fibers that carry information from the sensory receptors (including cutaneous sense organs in the skin, and proprioceptors in muscles and tendons) TO the CNS:
sensory (afferent) division
motor (efferent) division
Nerve fibers that carry impulses away from the CNS to effector organs (muscles and glands) and/or viscera:
sensory (afferent) division
motor (efferent) division
The motor (efferent) division has 2 subdivisions. Which part is voluntary- consciously controls skeletal muscles?
Somatic Nervous System
Autonomic Nervous System
The motor (efferent) division has 2 subdivisions. Which part is involuntary: automatically controls smooth and cardiac muscles and glands; further divided into sympathetic and parasympathetic nervous systems?
Somatic Nervous Systems
Autonomic Nervous Systems
Support cells in the CNS are grouped together as ________.
neuroglia
astrocytes
microglia
Nervous tissue is made up of two principal cell types. What are they?
neuroglia, or glial cells, or glia
neurons
astrocytes
microglia
Which cell type is the most abundant and versatile neuroglia?
neuron
astrocyte
microglia
ependymal
Microglia are phagocytes that defend CNS cells.
true
false
Where can the CNS glial cell type ependymal cells be found?
line cavities of the brain and spinal cord
around the nerve fibers in the CNS
Where can the CNS glial cell type oligodendrocyte be found?
wrapped around nerve fibers in the CNS- produce myelin sheaths
lining the cavities of the brain and spinal cord
PNS glial cells- Schwann cells:
form myelin sheath around nerve fibers in the PNS
protect and cushion neuron cell bodies
PNS glial cells- Satellite cells:
form myelin sheath around nerve fibers in the PNS
protect and cushion neuron cell bodies
Which region of the neurons (nerve cells) include the nucleus and metabolic center of the cell?
cell body
processes
Which region of the neurons (nerve cells) include the fibers that extend from the cell body?
cell body
processes
Neurons- processes- which part of the processes conduct impulses toward the cell body? *may have hundreds of these
dendrites
axons
synaptic cleft
synapse
Neurons- processes- which part conducts impulses away from the cell body?
dendrites
axons
synaptic cleft
synapse
Neurons- processes- which part is the gap between axon terminals and the next neuron?
dendrites
axons
synaptic cleft
synapse
Neurons- processes- which part is the functional junction between nerves where a nerve impulse is transmitted?
dendrites
axons
synaptic cleft
synapse
What is the following definition of? White, fatty material covering axons, protects and insulates fibers, speeds nerve impulse transmission
myelin
cholesterol
What 2 cell types utilize or produce myelin sheaths?
Schwann cells
oligodendrocytes
satellite cells
ependymal cells
Neuron terminology: clusters of bodies in the CNS
nuclei
ganglia
tracts
nerves
Neuron terminology: collections of cell bodies outside the CNS in the PNS
nuclei
ganglia
tracts
nerves
Neuron terminology: bundles of nerve fibers in the CNS
tracts
nerves
white matter
gray matter
Neuron terminology: bundles of nerve fibers in the PNS
tracts
nerves
white matter
gray matter
Neuron terminology: collections of myelinated fibers (tracts)
tracts
nerves
white matter
gray matter
Neuron terminology: mostly unmyelinated fibers and cell bodies
nuclei
white matter
gray matter
nerves
What are interneurons (associated neurons) and what do they do?
cell bodies located in the CNS
connect sensory and motor neurons
axons
In the functional properties of neurons, _________ is the ability to respond to a stimulus and convert it to a nerve impulse.
irritability
conductivity
In the functional properties of neurons, ________ is the ability to transmit the impulse to other neurons, muscles, or glands.
irritability
conductivity
How is a nerve impulse generated? What is the beginning "step" of the process?
the plasma membrane is at rest and is inactive (polarized)
fewer positive ions are inside the neuron's plasma membrane (K+ is the major positive ion INSIDE the cell, Na+ is the major positive ion OUTSIDE the cell)
a stimulus changes the permeability of the neuron's membrane to sodium ions
sodium channels are now open, and sodium (Na+) diffuses into the neuron
the inward rush or sodium ions changes the polarity at that site and is called depolarization
When a nerve pulse is being generated, what happens during action potential initiation and generation?
a stimulus changes the permeability of the neuron's membrane to sodium ions
sodium channels now open, and sodium (Na+) diffuses into the neuron
the inward rush of sodium ions changes the polarity at that site and is called depolarization
a graded potential (localized depolarization) exists where the inside of the membrane is more positive and the outside is less positive
if the stimulus is strong enough and sodium influx great enough, local depolarization activates the neuron to conduct an action potential (nerve impulse)
If enough sodium enters the cell, the action potential (nerve impulse) starts and is propagated over the entire axon. What is this step of nerve impulse generation called?
propagation
initiation
generation
Do fibers with myelin sheaths conduct nerve impulses faster than without?
yes
no
Nerve impulse: membrane permeability changes again becoming impermeable to Na+ ions and permeable to K+ ions. K+ ions rapidly diffuse out of the neuron, involves restoring the inside of the membrane to a negative charge and the outer surface to a positive charge, initial conditions of Na+ and K+ ions are restored using the sodium-potassium pump which uses ATP, 3 Na+ ions are ejected from the cell and 2 K+ ions are returned to the cell, until this phase is completed a neuron cannot conduct another nerve impulse
repolarization
initiation
generation
propagation
Put these steps in the correct order for signal transmission at the synapse: 1. Ion channel opens 2. Ion channel closes 3. Action potential arrives 4. Neurotransmitter is released into synaptic cleft 5. Vesicle fuses with plasma membrane 6. Neurotransmitter binds to receptor on receiving neuron's membrane
3, 5, 4, 6, 1, 2
1, 2, 3, 4, 5, 6
6, 2, 3, 4, 1, 5
5, 3, 2, 6, 1, 4
Traumatic brain injury: slight brain injury, typically little permanent brain damage occurs
concussion
contusion
Traumatic brain injury: marked nervous tissue destruction occurs, coma may occur
concussion
contusion
Traumatic brain injuries: death may occur after head blows due to which of the following?
concussion
contusion
intracranial hemorrhage
cerebral edema
What results when blood circulation to a brain area is blocked and brain tissue dies?
cerebrovascular accident (CVA) aka stroke
transient ischemic attack (TIA)
hemiplegia
aphasia
What is characterized by temporary brain ischemia (restriction of blood flow) and numbness, temporary paralysis, and impaired speech?
Transient ischemic attack (TIA)
cerebrovascular accident (CVA) aka stroke
hemiplegia
aphasia
What is characterized by one-sided paralysis?
hemiplegia
aphasia
What is caused by damage to the speech center in the left hemisphere?
hemiplegia
aphasia
What is defined as "increase in brain volume due to an increase in water content?"
cerebral edema
TIA
CVA
Which type of brain edema is most common and results from increased permeability of the blood-brain barrier?
vasogenic
cytotoxic
interstitial/hydrocephalic
Which type of brain edema is characterized by intracellular swelling due to increased cellular concentration of osmotically active solutes, affects both gray and white matter, often a complication of hypoxia/ischemia because of failure of the ATP-dependent sodium pump in affected cells?
vasogenic
interstitial/hydrocephalic
cytotoxic
Which type of brain edema is characterized by an accumulation of CSF in extracellular spaces of periventricular white matter, usually results from obstructed flow of CSF, volume of periventricular white matter reduced, and many be reversible by shunting?
vasogenic
cytotoxic
interstitial/hydrocephalic
What disease state has autoantibodies that bind acetylcholine receptors on motor end plates of muscle, block the normal binding of acetylcholine and induce complement-mediated lysis which results in progressive weakening of skeletal muscles. Treatment for this is aimed at increasing acetylcholine levels, decreasing antibody production and/or removing antibodies?
Myasthenia gravis
CVA
TIA
What is a plexus?
generic of a Lexus
networks of nerves serving motor and sensory needs of the limbs
How many plexuses are there?
1
2
3
4
Select the plexuses from the choices below:
cervical
brachial
lumbar
sacral
thoracic
The ANS has a chain of 2 motor neurons called:
preganglionic
postganglionic
sympathetic
parasympathetic
What is the sympathetic division also known as?
thoracolumbar division
splanchnic nerves
Preganglionic neurons originate from T1 though L2- axons pass through a __________________ to enter a sympathetic trunk ganglion.
rams communicans
medulla oblongata
foramen ovale
After synapsing at the ganglion, the axon may synapse with a second neuron at the same or different level (role of ganglia is to provide a gateway to effect multiple organ systems and/or an entire organ system based on signals from the brain through preganglionic nerve fibers.) Alternatively, the preganglionic neuron may pass through the ganglion without synapsing and form part of the splanchnic nerves.
true
false
What do parasympathetic fibers release?
acetylcholine
norepinephrine
What do sympathetic postganglionic fibers release?
acetylcholine
norepinephrine
What do preganglionic axons of both divisions of the ANS release?
acetylcholine
norepinephrine
What is another name for parasympathetic fibers?
cholinergic
adrenergic
What is another name for sympathetic fibers?
cholinergic
adrenergic
G-protein coupled receptor/serpentine/7-membrane spanning receptor
Alpha, beta and muscarinic receptors
Nicotinic receptor
Multisubunit channel (made up of multiple peptides/proteins, ligand gated ion channel (non-selective cation channel), depending on how the subunits are arranged or included, different cations may may use the channel.
Alpha, beta and muscarinic receptors
Nicotinic receptor
Norepinephrine (NE) and Epinephrine (E)
binds to alpha (1,2) and beta (1,2) receptors
binds to muscarinic and nicotinic receptors
Acetylcholine
binds to alpha (1,2) and beta (1,2) receptors
binds to muscarinic and nicotinic receptors
Which ANS division is considered the "fight or flight" division, meaning a response to unusual stimulus when emotionally or physically stressed or threatened?
sympathetic
parasympathetic
Sympathetic division takes over to increase activities. The "E" division.
exercise
excitement
emergency
embarrassment
Which ANS division is considered the "housekeeping" or "rest-and-digest" system?
sympathetic
parasympathetic
Which ANS division maintains daily necessary body functions such as digestion, defecation, and diuresis?
sympathetic
parasympathetic
The sympathetic and parasympathetic systems have the same effects, therefore when PNS is "on" SNS is also "on."
true
false
Norepinephrine stimulates alpha and beta receptors of the effector cell but also binds to alpha and beta receptors on parasympathetic termini which inhibits the release of Ach.
true
false
ACh release stimulates cholinergic receptors on the effector cells but also binds to cholinergic receptors on sympathetic termini to stimulate release of NE.
true
false
Do beta blockers lower blood pressure?
yes
no
Severe congenital brain diseases include: hydrocephalus- abnormal increase in the intracranial volume of CSF associated with dilation of the ventricular system.
true
false
Brain mass declines with age. Why?
Neurons die through life and are not replaced
adults are always dehydrated
