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IGCSE - Inheritance

Total questions: 40

Worksheet time: 26mins

Name
Class
Date
1.

What is the definition of the phenotype?

a)

The physical traits of an organism

b)

The genetic makeup of an organism

c)

The letters eg, Aa

d)

How the genotype is expressed.

2.

What is the definition of an allele?

a)

An allele is a variety of a gene.

b)

An allele is the genetic makeup of an organism

c)

An allele is another word for a gene.

3.
An allele whose trait only shows up when no dominant allele is present.
a)
hidden allele
b)
dominant allele
c)
recessive allele
d)
present allele
4.

A gene is...

a)

A heritable factor that controls a specific characteristic

b)

An allele

c)

A length of DNA which occupies a specific position on the chromosome

5.

What is the law of dominance?

a)

One of the pairs of inherited traits will be dominant and the others recessive unless both the factors are recessive.

b)

There will always be a dominant allele.

c)

One of the pairs of inherited traits will be dominant and the others recessive.

6.

What is the definition of heterozygous?

a)

When both alleles are dominant

b)

When one allele is dominant and one is recessive.

c)

When both alleles are recessive.

d)

When one gene is dominant and one is recessive.

7.

In cats, the allele for stripes (S) is dominant over the allele for no stripes (s). Two heterozygous cats are bred. If the female cat has a litter of 8, predict how many kittens will have no stripes.

a)

2

b)

6

c)

4

d)

8

8.

In guinea pigs, the allele for short hair (H) is dominant and the allele for long hair (h) is recessive. When a dominant homozygous male and a heterozygous female are bred together, what is the predicted phenotypic ratio for the offspring?

a)

1:1 short hair to long hair

b)

All have short hair

c)

1:3 short hair to long hair

d)

1:3 long hair to short hair

9.

What word is used to describe a thread-like structure of DNA that carries genes?

a)

nucleus

b)

chromosome

c)

genotype

d)

phenotype

10.

When carrying out a test cross, what is the organism of unknown genotype always crossed with?

a)

homozygous dominant (e.g. RR)

b)

heterozygous (e.g. Rr)

c)

homozygous recessive (e.g. rr)

d)

all three of these can be used

11.

Cystic fibrosis is a lung disease caused by a recessive allele, c.


Two healthy parents produce a child with cystic fibrosis.


Which of the following statements must be true?

a)

One parent must be homozygous and the other must be heterozygous

b)

Both parents must be homozygous

c)

One parent must be homozygous and the other must be heterozygous

d)

Both parents must be heterozygous

12.



(a)  

13.
a)

HH x HH

b)

Hh x Hh

c)

Hh x hh

d)

hh x hh

14.

Which process involves meiosis?

a)

growth of cells

b)

production of gametes

c)

repair of damaged tissues

d)

replacement of cells

15.
a)

1 and 3

b)

1 and 4

c)

3 and 4

d)

2 and 3

16.

State the genotype of person P

a)

Xh Xh

b)

XH Xh

c)

XH XH

d)

XH Y

e)

Xh Y

17.
In Mendel's first experiment, he crossed two a purple flower with a white flower. What were the F1 generation phenotypes?
a)
100% purple
b)
100% white
c)
75% purple, 25% white
d)
75% white, 25% purple
18.

A man of genotype IAIo and woman of genotype IBIo have a child.


What is the chance that the child will have the same blood group as one of its parents?

a)

0

b)

1 in 4

c)

1 in 2

d)

3 in 4

19.

Which of the following statements are true of codominance?


I. Both alleles are expressed in a person who is heterozygous


II. More than two phenotypes are usually possible


III. The ABO blood group system is an example of it

a)

I and II only

b)

I and III only

c)

II and III only

d)

I, II and III

20.

Gary and Fiona are both healthy but produce a child with a genetic disease caused by a recessive allele.


Which of the following must be true?

a)

The child could be heterozygous

b)

Gary is homozygous and Fiona is heterozygous

c)

Gary and Fiona are both homozygous

d)

Gary and Fiona are both heterozygous

21.

Albinism is humans us caused by a recessive allele. It causes the skin and hair to appear white.


Parents who do not have this condition produce a child with abinism.


What is the probability that their second child will be born with albinism?

a)

25%

b)

50%

c)

75%

d)

100%

22.

The pedigree chart shows the inheritance of a genetic disorder in a family.


What conclusion can be made about this genetic disease?

a)

The genetic disorder is dwarfism

b)

It is caused by a dominant allele

c)

It is caused by a recessive allele

d)

It is caused by codominant alleles

23.

Which of the following genotypes are possible for a person of blood group A?


I. IA IA

II. IA IB

III. IA IO

a)

I and II only

b)

I and III only

c)

II and III only

d)

I, II and III

24.

Coat colour in a certain mammal is determined by two codominant alleles of a gene.


Allele B produces a black coat and allele W produces a white coat.


What would you expect the phenotype to be of a mammal who is heterozygous for this gene?

a)

Black only

b)

White only

c)

Black spots and white spots

d)

Grey

25.

Patrick is blood group AB.


Samantha is blood group A. However, her father was blood group O.


They have a child.


What is the probability that this child has the same blood group as Patrick or Samantha?

a)

25%

b)

50%

c)

75%

d)

100%

26.

In a certain plant, the allele fo white fruit (W) is dominant over the allele for yellow fruit (w).


A white-fruited plant was crossed with a yellow-fruited plant.


About half of the offspring were white-fruited and the other half were yellow-fruited.


Which genotypes did the parent plants have?

a)

ww and www

b)

Ww and ww

c)

WW and ww

d)

WW and Ww

27.

The pedigree chart shows the inheritance of a genetic disorder in a family.


It is caused by a recessive allele.


Which person in this pedigree chart has two possible genotypes?

a)

Martha

b)

Steven

c)

Peri

d)

Jack

28.

The diagram shows the inheritance of coat colour in pigs through three generations.


What is the most likely explanation of how coat colour in pigs is inherited?


I. codominant alleles are involved

II. sandy pigs are heterozygous

III. the allele for a red coat is dominant

a)

I and II only

b)

I and III only

c)

II and III only

d)

I, II and III

29.

One alternative form of a gene is called_______________

a)

a DNA

b)

a Phenotype

c)

a trait

d)

an allele

30.

this image is an example of

a)

codominance

b)

dominance

c)

incomplete dominance

d)

sex-linked

31.

What term is used to describe the alleles that a person carries for a gene

a)

genotype

b)

dominant

c)

phenotype

d)

recessive

32.

Which of the following is true of a recessive allele?


I. it is only expressed if the dominant allele is absent

II. two copies are needed to show its feature

III. it always causes a genetic disease

a)

I only

b)

I and II only

c)

II only

d)

I, II and III

33.

How many alleles for each gene are carried in the sex cells (gametes)?

a)

1

b)

2

c)

3

d)

4

34.

Tall (T) is dominant over dwarf (t) in a species of plant. A tall plant has an unknown genotype. Which plant should it be crossed with to ascertain this?

a)

TT

b)

Tt

c)

tt

35.

A brown eyed man of genotype Bb marries a blue eyed woman. What is the chance that their third child is brown eyed?

a)

25%

b)

50%

c)

75%

d)

100%

36.

A couple has 6 children but of them, 5 were boys. What reason explains why this deviates from the expected 3 boys : 3 girls ratio?

a)

The female suffers from a genetic disorder.

b)

The male only release sperms with the Y chromosome.

c)

The sample size is too small.

d)

The correct ratio is actually 5:1. There is nothing wrong.

37.

A couple has had 1 child, who is a boy. Which of the following statements is true?

a)

Their second child will be a girl because the ratio of boy:girl is 1:1.

b)

Their second child will be definitely be a girl because the chance of her being a girl is 50%.

c)

Their second child has a 50% chance of being either a boy or a girl as gender of the first child has no effect on the subsequent children.

38.

Coat color in a dog breed is determined by incomplete dominance where three colors are produced (Brown, tan and white), and the brown coat allele (B) has incomplete dominance over the white coat allele (b). Which offspring ratio would be expected from a cross between a brown dog and a white dog?

a)

A. 2 BB: 2 Bb

b)

B. 4 Bb

c)

C. 1 BB: 2 Bb: 1 bb

d)

D. 2 BB: 2 bb

39.

Human blood type is determined by multiple alleles (A, B, and O). Which ratio would result from a cross between a man with Type AB blood and a woman with Type O blood?

a)

A. 50% Type A, 50% Type O

b)

B. 75% Type A, 25% Type B

c)

C. 50% Type A, 50% Type B

d)

D. 100% Type O

40.
What percentage of the offspring will have this recessive disease?
a)
0%
b)
25%
c)
50%
d)
75%