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pharmaceutics exam 1

Total questions: 59

Worksheet time: 31mins

Name
Class
Date
1.

the amount of iron determined today in your blood sample was found to be 100 mcg/deciliter such iron content in a blood sample can be categorized as

a)

intensive

b)

extensive

2.

the 3rd law of thermodynamics deals with

a)

entropy at absolute zero

b)

thermal equilibrium

c)

conservation of energy

d)

enthalpy at absolute zero

3.

the equilibrium constant of a reaction is related to the reaction temperature by

a)

van't hoff equation

b)

gibb's law

c)

clausius-clapyeron equation

d)

hess's law

4.

second law of thermodynamics states that entropy of a system, undergoing spontaneous irreversible change, always increases

a)

true

b)

fasle

5.

which law of thermodynamics is described as the law of conversion of energy

a)

0 th

b)

1 st

c)

2 nd

d)

3 rd

6.

thermodynamics defines quantitative relationships between

a)

heat and mechanical energy

b)

heat and electrical energy

c)

heat and chemical energy

7.

adiabatic process can take place in

a)

thermally insulated system

b)

an isolated system

c)

a vacuum flask

8.

gibb's free energy equation should be used when a change in state is taking place at constant pressure

a)

true

b)

false

9.

the equilibrium constant of a reaction is know as 25C is it possible to determine the equilibrium constant of that reaction at 45C

a)

yes

b)

no

c)

depends on the enthalpy of the reaction

10.

holmholtz's free energy equation should be used when a change in state is taking place at constant pressure

a)

true

b)

false

11.

the heat absorbed by an isolated system at constant volume is used for

a)

bringing about change in internal energy

b)

bringing about change in internal energy and as well as for doing some useful work

12.

applications of free energy functions are

a)

calculations of equilibrium constants

b)

hess law of constant heat summation

c)

derivation of the vant hoff equation

13.

the increase in heat content of a system is equal to

a)

only heat absorbed by the system at constant temp

b)

only heat released by the system at constant pressure

c)

only heat absorbed by the system at constant volume

d)

either heat absorbed or released by the system at constant pressure

14.

if the work done by an isolated system is equal to the change in internal energy, then the energy gained or lost by the system is

a)

zero

b)

1 erg

c)

1 cal

d)

1 j

15.

what would be the internal energy of a system which is absorbing heat adiabatically

a)

increase

b)

decrease

c)

remain constant

16.

the lowest possible entropy of a substance can be seen at

a)

0 C

b)

0 K

c)

0 F

d)

273.16 K

17.

the concept of latent heat is valid only if the heat absorbed by a system is resulting into its change in phase

a)

true

b)

false

18.

select the correct statement involving 2nd law of thermodynamics

a)

the entropy change of reversible thermodynamic processes is always zero

b)

the entropy change of reversible thermodynamic processes is always positive

c)

the entropy change of reversible thermodynamic processes is sometimes zero

d)

the entropy change of reversible thermodynamic processes is always negative

19.

entropy of a system decresese with increase in randomness

a)

true

b)

false

20.

an angstrom unit A is equal to

a)

10^-10 m

b)

10^-5 cm

c)

10^-8 m

d)

10^-1 cm

21.

What would be the weight and mass of a 70 kg person in an elevator going down vertically at the acceleration

a)

weight= 686.7 kg x m/s²; mass=70 kg

b)

weight= 70 kg x m/s²; mass= 0 kg

c)

weight= 686.7 kg x m/s²; mass= 0 kg

d)

weight= 0 kg x m/s²; mass= 70 kg

22.

Solving (567¹⁴)¹/⁷ is best stated as which of the following

a)

antilog[(1/7) x 14 x log567]

b)

antilog[(1/7) x 7 x log567]

23.

log xy =

a)

log x + y

b)

log x + log y

c)

log x X y

d)

log X log y

24.

A statement such as "not more than 110.0 percent" in the official compendium of the U.S. Pharmacopia and National Formulary may mean 110.1 or 110.2 percent.

a)

true

b)

false

25.

the capillary rise method can be used to measure

a)

surface tension

b)

cohesive forces

c)

adhesive forces

d)

strength

26.

the surface and core of the micelles formed in an aqueous medium are

a)

hydrophilic and lipophilic

b)

amphiphilic and hydrophilic

c)

Lipophilic and amphiphilic

d)

Lipophilic and hydrophilic

27.

adsorption is a bulk phenomenon

a)

true

b)

false

28.

in the case of liquid-gas interface, if the cohesive forces between liquid-liquid are equal to the adhesive forces of liquid-air , the surface tension would be

a)

<0

b)

>1

c)

=1

d)

=0

29.

the dunouy tensiometer can be used to measure

a)

both the surface and interfacial tension

b)

Interfacial tension only

c)

Surface tension only

d)

Neither surface tension nor interfacial tension

30.

physical adsorption occurs due to

a)

Van der Waals attractive forces

b)

Interfacial bonds

c)

cohesive bonds

d)

chemical bonds

31.

The force required to detach the ring from the surface/interface, in the DuNouy ring method is recorded in

a)

dynes

b)

newtons

c)

pounds

d)

grams

32.

You will use the surfactant having HLB values shown below to prepare an emulsion of olive oil in water

a)

1-3

b)

3-7

c)

less than 9

d)

9-15

33.

Spans, sorbitans, esters have HLB values from

a)

0-1

b)

1.8-8.6

c)

9-12

d)

12-8

34.

HLB scale can be used to measure the following activity of a surfactant

a)

thermal activity

b)

vibrational activity

c)

surface activity

d)

molecular activity

35.

the higher the HLB value of an agent, the more lipophilic it is

a)

true

b)

false

36.

When a capillary tube is placed in a liquid, the level of liquid in the capillary tube feel to a lower level than that of the liquid outside the tube. This is because

a)

The adhesive forces between the liquid-glass and the cohesive forces between liquid-liquid are equal

b)

The cohesive forces between the liquid-liquid are greater than the adhesive forces between liquid-glass

c)

The adhesive forces between the liquid-glass are greater than the cohesive forces between liquid-liquid

d)

The adhesive forces between the liquid-glass are lower than the cohesive forces between liquid-liquid

37.

A molecule must be consisted of the following group(s) to possess surface activity

a)

A hydrophilic (water-loving) group

b)

A lipophilic (oil-loving) group

38.

Paclitaxel is an anticancer drug which is solubilized by using a surfactant named:

a)

tween 80

b)

tween 20

c)

span 80

d)

Cremophor EL

39.

The process by which a physically adsorbed gas is removed is called

a)

evaporation

b)

desorption

c)

solubilization

d)

sublimation

40.

the attractive forces present between _____ are called adhesive forces

a)

water-air

b)

water-water

c)

oil-oil

d)

air-air

41.

Activated charcoal is used as an antidote in drug poisoning because

a)

the adsorption by activated charcoal prevents bioabsorption by the GI tract

b)

the adsorption by activated charcoal causes elimination of drugs from the tissues into the GI tract by a process known as GI dialysis

42.

which of the following cannot be observed

a)

gas-gas

b)

gas-liquid

c)

liquid-gas

d)

solid-solid

43.

the temperature at which the vapor pressure of a liquid equals the external or the atmospheric pressure is called melting point

a)

true

b)

false

44.

iodine dissolves in water in the presence of KI this is due to ion-induced dipole intercation

a)

true

b)

false

45.

for real gases the collisions between particles is perfectly elastic

a)

true

b)

false

46.

The critical temperature and pressure for CO2 are 31C and 74.9 atm, respectively. Can you liquefy CO2 stored at 100C by applying pressure?

a)

yes

b)

no

47.

an unknown compound proceeds from the low melting metastable alpha form to the beta form having a higher melting point. however, in storage it was observed that the beta form reverted to the metastable alpha form. this kind of polymorphism is called monotropic

a)

true

b)

false

48.

the intermolecular distance in solid is

a)

less than that in both liquid and gas

b)

higher than that in both liquid and gas

c)

higher than liquid but less than gas

d)

higher than gas but less than liquid

49.

compound A was recrystallized from isopropyl alcohol to give a compound B, which had a rhombic cyrstalline appearance. the compound B showed a very high melting point compared to A. Compound B is

a)

a polymorph of compound A

b)

Is not a polymorph of compound A

c)

a pseudopolymorph of compound A

d)

none of the above

50.

the temperature at which the vapor pressure of a liquid equals the external or the atmospheric pressure is known as

a)

freezing point

b)

boiling point

c)

critical temperature

d)

melting point

51.

the forces that bind molecules include

a)

repulsive and attractive forces

b)

van der waals forces

c)

ion-dipole and ion-induced dipole forces

d)

hydrogen bonds

52.

Clausius-Clapeyron equation for liquids establishes relationships between

a)

vapor pressure and absolute temperature

b)

freezing point and absolute temperature

c)

vapor pressure and degrees celsius temerature

d)

volume and absolute temperature

53.

polymorphs are same substance but in different crystalline forms which are characterized by different

a)

melting points

b)

x-ray diffraction patterns

c)

solubility

54.

sodium chloride and methane are

a)

covalent and covalent compound

b)

electrovalent and covalent compound

c)

electrovalent and electrovalent compound

d)

covalent and electrovalent compound

55.

a substance which is bound together by weak forces is said to have

a)

low heat of fusion and low melting point

b)

High heat of fusion and high melting point

c)

High heat of fusion and low melting point

d)

Low heat of fusion and high melting point

56.

the high boiling point of water is due to hydrogen bonding

a)

true

b)

false

57.

autoclave is an equipment used in hospitals for sterilization of surgical instruments. this has a pressure valve using which user-selectable pressure greater than atmospheric pressure can be applied. water boils inside an autoclave at

a)

higher or lower than 100C

b)

higher than 100C

c)

lower than 100C

d)

100C

58.

in a pressure cooker, water boils at

a)

100C

b)

higher than 100C

c)

lower than 100C

d)

higher or lower than 100C

59.

for a single component system, with 3 phases in equilibrium at the triple point, the degree of freedom is

a)

0

b)

3

c)

1