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WorksheetsHeart, Blood, Lymphatic System
Total questions: 117
Worksheet time: 1hrs 1mins
Basophils have a _____ shape nucleus, Eosinophils have a _____ shaped nucleus and Neutrophils have ______ nucleus.
Bilobed, S shaped, 3-5
S shaped, Bilobed, 3-5
S shaped, Bilobed, 2-4
B cells remain in the ___ for maturation.
thymus
bone marrow
blood stream
liver
T cells leave bone marrow to go to the ____ for maturation.
spleen
liver
kidneys
thymus
Which leukocytes are phagocytic
Monocytes, Neutrophils, Eosinophils
Basophils, Lymphocytes
Lymphocytes, Eosinophils, Basophils
Monocytes only
Where are T cells formed?
Thymus
Bone marrow
Liver
Heart
The lymph node is?
acquired, adaptive, specific
innate, lymph nodes, tonsils
Complement proteins are in the?
Liver
Spleen
Kidneys
Small intestines
Fluid in the lymphatic vessels is known as (a) ?
Most of the lymphatic trunk drains into _____; drains all of left side of upper body into junction of left ____ ____ and left ____ ____
left subclavian trunk, thoracic duct, jugular trunk
thoracic duct, broncho- mediastinal trunk, lymph nodes
thoracic duct, internal jugular, subclavian vein
Remaining trunk of lymph trunk drain into right ____ _____ that drains into junction of right ____ ____ and right ____ ____
lymphatic duct, internal jugular, subclavian vein
subclavian vein, internal jugular, thoracic duct
thoracic duct, internal jugular, subclavian vein
What percentage of interstitial fluid drains into lymphatic capillaries?
5%
30%
10%
50%
Where do dietary fats go after entering lymphatic capillaries?
small intestines
large intestines
spleen
thymus
Where do lymphoid organs filter pathogens?
only lymph
only blood
both
neither
The capillary in small intestines is called ____ and collects ____.
lacteal, fat
fibers, oxygen
lacteal, carbon dioxide
T cells, fat
The lymph vessel has ____ muscle.
reticular
cardiac
skeletal
smooth
Blood vessels have no end but lymph vessels have an end.
True
False
What type of connective tissue do lymphoid tissue have that interweave and form nets that trap disease causing pathogens?
nervous
reticular
dendritic
____ engulf foreign materials and initiate immune response.
monocyte
macrophages
pathogens
immunoglobulins
What does MALT stand for?
Mucosa associated lymphatic tissue
Mucosa atypical leukemia tissue
Mucosa associated lymphatic T-Cell
Macrophage associated lymphatic tissue
Choose the answer that best describes the role of the Peyer's Patch.
Small masses of lmyphatic tissue that help monitor and prevent the growth of pathogenic bacteria in the small and large intestines.
Loosely organized clusters of lymphoid tissue that have a wet membrane that are used to being exposed to pathogens.
A hormone that helps maturing T cells
The appendix is a 2 ended tube that filters and looks out for foreign things.
True
False
What is found inside the lymph node?
macrophages
lymphocytes
dendritic cells
osteocytes
Does the spleen detect pathogens?
Yes
No
Does the Thymus detect pathogens?
Yes
No
In the spleen, what type of pulp contains macrophages that destroy old erythoctyes
Red
White
Yellow
In the spleen, what kind of pulp filters pathogens from blood that contain leukocytes and dendritic cells?
Red
White
hypersensitive
cytokine
The thymus secretes a hormone called thymosin. Select all that are true about this hormone.
Most active in adults
Most active in children
Atrophy occurs when you become older
by 65 we have about 2% of T cell production
Which line of defense is innate, has barriers that block pathogen and is made of the skin/mucous membrane.
1st line of defense
2nd line of defense
3rd line of defense
1st and 2nd line of defense
Which line of defense is innate, response to inflammation, complement proteins and antimicrobial substances.
1st line of defense
2nd line of defense
3rd line of defense
Which line of defense is adaptive/acquired immunity and has specialized lymphocytes?
1st line of defense
2nd line of defense
3rd line of defense
1st line and 3rd line of defense
Which one does NOT apply to Cutaneous membranes?
Slightly basic pH
contain sebum
several layers of epithelial tissue
Pick which one is FALSE about mucous membranes
made of 3-5 layers of cells
lines the stomach, mouth and nose
one layer of cells
kills pathogens
Which leukocyte responds to parasitic pathogens?
Basophil
Eosinophil
Monocyte
Macrophage
Which one is usually the first responder to cellular injury?
neutrophil
natural killer cells
macrophage
sinusoidal capillary
Which leukocyte releases chemicals to fight off pathogens?
Basophil
Neutrophil
Macrophage
Lysosome
Who recognizes cancerous cells and viruses
Natural killer cells
Basophils
Dendritic cells
Neutrophils
Complement protein are made by
kidneys
lymph node
spleen
liver
Interferons job is to?
Interfere with viral replications
activate other WBc's to serve as messages
secrete macrophages in response to bacteria and pathogens.
Interleukons are chemicals made by white blood cells to activate?
natural killer cells
c3b
other white blood cells
b cells
What sets the bodies temperature back to 38 degrees celsius after a fever?
bradykinin
chemotaxis
pyrogens
thymosin
Lymphedema is the dysregulation of interstitial fluid; the arms and legs are usually affected.
True
False
Check off the facts for type 1 diabetes in autoimmune disorders.
pancreas cannot create insulin
the immune system turns itself on itself and binds to self antigens (sees them as foreign)
immune cells see pancreas as antigens therefore destroying it
do not need insulin shots
Check off facts about AIDS.
take down lymphocytes
B cells get destroyed
T cells get destroyed
Active immunity produces memory cells naturally or through a vaccine meaning they are protected ___?
forever
one time
for one year only
Passive immunity occurs naturally such as igG passed through mothers milk, or artificially through injection with antibodies. The memory is?
one time
forever
never
depends on the blood type
Atrial Natriuretic Peptide is produced by the ___. ANP is a hormone that ___ blood pressure by increasing urination through decreasing Na+ retention in the kidneys.
pulmonary trunk, increases
atria, decreases
atria, increases
aorta, decreases
The pulmonary system is on the ___ side and the system system is on the __ side
right, left
left, right
right, right
left, left
Right atrium receives blood from the superior and inferior vena cava?
True
False
The interventricular sulcus has a depression between the?
right and left ventricles
the atria and ventricles
Vessels are ____ and arteries are ____?
away from the heart, towards the heart
towards the heart, away from the heart
Which node is responsible for starting the heart rate in the right atrium?
SA node
AV node
SL node
Purkinje node
Contractile cells pump __, pacemaker cells are responsible for __.
1%, 99%
99%, 1%
Which one is the middle layer of the heart tissue?
endocardium
pericardium
myocardium
The endocardium is composed ___ tissue while the myocardium is composed of ___ tissue.
simple squamous epithelium, dense irregular CT
simple cuboidal epithelium, smooth connective tissue
The left atrium is thicker than the right atrium.
True
False
Pulmonary veins drain oxygenated blood into the ___?
Left ventricle
Right atrium
Right ventricle
Left atrium
What is the role of the chordae tendineae?
prevent the blood from back flow
contract the heart muscle
hold the valve in place; provides structure
The right AV valve is called the tricuspid valve and the left AV valve is called the bicuspid or mitral valve.
True
False
Pacemaker cells are found in?
SA node
AV node
Both
none
Put the Action Potential phases in order:
1. Repolarization phase
2. Full depolarization phase
3. Slow initial depolarization phase
4. Minimum Potential Phase (resting)
3, 2, 1, 4
1, 2, 3, 4
4, 1, 2, 3
3, 2, 4, 1
Which action potential phase is it when cation + channels open allowing Na+ to leak into the cell and K to leak out?
Repolarization Phase
Slow initial depolarization phase
Resting potential phase
Which type of junction in the intercelated discs allow for Action Potentials to pass from Pacemaker cells to Contracticle cells?
Tight Junction
Gap Junction
Electrical Junction
Put these in order for Electrophysiology of Contractile cells:
1. Repolarization phase
2. Initial repolarization phase
3. Platea phase
4. Rapid depolarization phase
4, 3, 2, 1
4, 2, 3, 1
4, 1, 2, 3
1, 4, 3, 2
In the plateau phase, how many mv is the depolarization at?
-20-0mv
+10-0mv
-10-0mv
+20-0mv
In the repolarization phase of Contractile cells, both Na+ and Ca+ channels return to resting state and K+ channels open at __ mv.
-85mv
-60mv
-45mv
+80mv
In what stage are k+ channels open for a brief period of time in Contractile cells?
stage 1. rapid depolarization
stage 2. initial repolarization phase
stage 3. plateau phase
stage 4. repolarization phase
Tetany (no contraction) occurs during which phase?
Repolarization phase
Slow initial depolarization phase
Plateau phase
P wave is the first wave that depolarizes all cells in the atria except the ____ node.
SA
AV
The QRS complex is the place where ventricular repolarization occurs
True
False (depolarization)
The T wave represents?
ventricular depolarization
ventricular repolarization
plateau phase
When the ventricles are relaxing, the pressure in the atria is ___ and the semilunar valves are ___.
High, open
High, closed
Low, open
Low, closed
When the ventricles are relaxed, the end diastolic preload volume is at __ ML.
0 ML
10 ML
30 ML
120 ML
During atrial systole (contraction), how much ML of blood is being pushed into the ventricles?
100 ML
80 ML
120 ML
20 ML
Does blood stay the same during ventricular isovolumetric contraction?
yes
no, it goes down
no, it goes up
During ventricular isovolumetric contraction, what happens to the valves?
they all open
they all close
semilunar valves open
av valves open
During systole ejection phase how many ML of blood are in the ventricles?
70 ML
60 ML
30 ML
10 ML
During End systolic volume, how many ML of blood remain?
90 ML
120 ML
20 ML
50 ML
Check off the facts of Cardiac output.
Amount of blood pumped into pulmonary and systemic circuit in 1 minute
determined by stroke volume x heart rate
determines the percentage of red blood cells there are compared to the whole blood
determined by EDV - ESV
How do we determine Stroke Volume?
End diastolic volume (120 ML) - End systolic Volume (50 ML) = 70 ML
End systolic Volume (50 ML) - End diastolic volume (120 ML) = -70 ML
Where does the coronary sinus receive blood from?
pulmonary vein
great cardiac vein
anterior interventricular vein
The P wave is the atria depolarization phase and the QRS complex is responsible for the ventricular depolarization and atrial repolarization phase.
True
False
High pressure in the pulmonary trunk and aorta make the ___ valves close.
Semilunar valves
Av vavles
What determines the preload; length or degree of stretch of sarcomeres in ventricular cells before they contract?
EDV
ESV
SA node
AV node
In the sympathetic nervous system, the hormones that increases cardiac output is?
Epinephrine
Acetylcholine
Aldosterone
Norepinephrine
The parasympathetic nervous system innervates heart by the vagus nerve X and releases _____ hormone that affects SA node by decreasing its rate of action potential generation.
acetylcholine
epinephrine
glucagon
antidiuretic hormone
In the sympathetic system in the Adrenal Medulla, it secrets NE and E which will cause:
heart rate to go up
stroke volume to go down
stroke volume to go up
heart rate to go down
ANP decreases blood volume and preload and therefore ___ cardiac output
increases
decreases
The hormone such as aldosterone and antidiuretic hormone increase blood volume and preload and so ___ cardiac output
decrease
increase
If body temperature goes down then the parasympathetic will ____?
increase
decrease
If body temperature goes up then the sympathetic will ___?
increase
decrease
The buildup of plaques is called?
coronary artery disease
peripheral artery disease
ischemia disease
Plasma makes 55% while formed elements make 45%
True
False
RBC count
4.2-6.2 million
250-400 thousand
5-10 thousand
100-200 million
WBc count
5-10 thousand
250-400 thousand
Platelet count:
100-200 thousand
250-400 thousand
4.2-6.2 million
Percentage of each WBC
Neutrohpil %=
Lymphocyte %=
Monocyte %=
Eosinophil %=
Basophil %=
(a)
What is the percentage of Erythrocytes in formed elements?
1%
45%
44%
15%
3 leukocytic phagocytes?
monocyte
neutrophil
basophil
eosinophil
Platelets are developed into megakaryocytes (thrombopoiesis) that have a life span of ____ days and are removed from circulation by the ___ and ____.
7-10 days, kidney and spleen.
1-3 days, liver and spleen
5-7 days, liver and kidney
7-10 days, liver and spleen
Hemoglobin amount in woman vs men?
14-18 vs 12-16 g/dL
12-16 vs 14-18 g/dL
24-32 vs 48-56 g/dL
How long does it take for blood to start clotting?
11-13 seconds
1-3 seconds
10-20 minutes
2-5 seconds
When does clotting start?
Platelet plug formation
Coagulation
What is the life span of a RBC?
100-500 days
100-120 days
5-7 days
20-40 days
In the intrinsic pathway, proteins are already found in the blood. XII (12) activates __ and ___
XI (11) and IX (9)
VI (6) IX (9)
Calcium activates protein?
11
7
4
10
During erythrocyte death, erythrocytes are trapped in sinusoids of the ___ and ___ digest them.
spleen, monocytes
spleen, macrophages
liver, natural killer cells
spleen, natural killer cells
What can be reused to make new proteins?
amino acids
platelets
Where is Bilirubin sent for excretion of bile?
kidneys
small intestines
liver
large intestines
Blood clotting is a ___ feedback.
positive
negative
Which type of capillary has no holes, is most common and has tight junctions?
fenestrated
continuous
sinusoidal
To find NFP you must subtract hydrostatic pressure form osmotic pressure.
(35mmHg-22mmHg =13 mmHg)
True
False
Atherosclerosis is the buildup of fat, calcium and salts in the tunica ___
media
intima
externa
What type of antigen do macrophages carry? Who exocytosed into them?
MHC II, neutrophils
MHC I, basophils
Naive B. cells that encounter their Ags become activated, B cells bind to a T _ to become fully activated.
T c
T h (helper cell)
In innate immunity, T helper cells secrete cytokine interleukin _ and cause macrophages to produce interleukin _ in order to generate more interleukin 3 which is an example of ____ feedback regulation.
2, 3, negative
3, 12, positive
3, 12, negative
In adaptive immunity, T helper cells secrete cytokine interleukin _ that is required to activate Tc cells. T helper cells directly bind to B cells and stimulate them to proliferate and differentiate.
3
12
6
2
T c cells generally interact only with class 1 or class 2 MHC molecules?
MHC I (found on surface of plasma membrane on nucleated cell)
MHC II ( found on surfaces of Ag presenting cells)
