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Pharm quiz

Total questions: 85

Worksheet time: 50mins

Name
Class
Date
1.

Airway mucus consists of

a)

Secretary (goblet) cells

b)

Submucosal glands

c)

Cilia in lower airways

d)

Phlegm

2.

Secretary (Goblet Cells) …

a)

Produce mucus on airway surface

b)

Produces mucin in large cartilage airways

c)

Drives mucus from airways

d)

Mucus cleared by cough

3.

Submucosal glands

a)

Produce mucin in large, cartilage airways

b)

Produce mucus on airway surface

c)

Drives mucus from airway

d)

Mucus cleared by cough

4.

Cilia in lower airways …

a)

Drives mucus from airways

b)

Mucus cleared by cough

c)

Produce mucus on Airway surface

d)

Produce mucin in large cartilage airways

5.

Phlegm (sputum)

a)

Inflammatory cells

b)

Bacteria

c)

DNA

d)

Secretary Cells

6.

Diseases associated with mucus dysfunction

a)

Asthma

b)

COPD

c)

Cystic Fibrosis

d)

Broken Ribs

7.

Mucoactive medications

a)

Encourage mucus clearance

b)

Disrupts Mucus molecules

c)

Should be considered after therapy to decrease infection & inflammation

8.

Mucoactive medications are characterized by mechanisms of action:

a)

bland aerosols

b)

Expectorant

c)

Mucolytes

d)

Mucokinetic

e)

Secondary treatment: adequate hydration

9.

What’s the purpose of bland aerosol?

a)

Humidify with Saline

b)

Sputum induction

c)

Break apart mucus

10.

How are bland aerosol administered?

a)

SVN (dilute)

b)

LVN

c)

submucosal

d)

Intravenous

11.

What are bland aerosols used for?

a)

Bronchoconstriction

b)

Airway hyperesponsiveness

c)

Reserve lung function

12.

Complication of bland aerosols

a)

Bronchospasm

b)

Bronchoconstriction

c)

Infection

d)

Over hydration

e)

Airway edema

13.

Bland aerosol agents :

a)

Normal saline

b)

Hypotonic saline

c)

Hypertonic saline

d)

Sterile distilled water

e)

Anticholinergics

14.

Normal saline has ___ % sodium chloride (NaC1)

a)

0.9

b)

0.45

c)

3

d)

5

15.

hypotonic saline has ___% NaC1 ( half normal saline)

a)

45%

b)

0.9%

c)

1%

16.

Hypertonic saline most common % of Sodium Chloride

a)

3%

b)

5%

c)

7%

d)

10%

e)

15%

17.

Normal saline has the ____ osmotic pressure as bodily fluids.

a)

Same

b)

Opposite

18.

Normal saline is the most common saline to dilute _____ drugs.

a)

Bronchodilator

b)

narcotics

c)

Amphetamines

19.

Normal saline is unlikely to cause bronchospasm

a)

True

b)

False

20.

Sodium content is important consideration for ____ patients

a)

Cardiac

b)

Acid reflux

c)

Broken limb

d)

Surgical

21.

What may be preferred for cardiac patients ?

a)

Sterile distilled water

b)

Morphine

c)

Hydrocortisone

22.

Hypotonic osmotic pressure ____ than body fluids

a)

Lower

b)

Greater

23.

Indications for hypotonic saline

a)

Use in LVN when patient can’t tolerate sterile distilled water

b)

Diluent in case of severe salt restrictions

c)

reserving lung function

24.

Hypertonic saline osmotic pressure ___ than body fluids

a)

greater

b)

Lower

25.

Hypertonic saline is used for

a)

Sputum induction

b)

Damages mucoactive mucus

26.

Hypertonic saline comes in :

a)

Aerosol form

b)

Irritates airway

c)

Attracts humidity

27.

What percentage of NaC1 solution do you give someone with cystic fibrosis?

a)

10%

b)

5%

c)

7%

28.

What is sterile distilled water used for

a)

Agent for LVN for humidification of respiratory tract

b)

Diluent for SVN treatments with bronchodilators or other potent drugs

c)

Distrupting mucus molecules

29.

Mucolytic agents

a)

Disrupts mucus molecules

b)

Damages cells in mucus

c)

Causes mucolysis

d)

Effects composition of pulmonary secretions

e)

Causes bronchoconstriction

30.

Mucolytic Agents:

a)

N-acetyl-L-cysteneine (NAC) (Mucomyst)

b)

Proteolytics

c)

Dornase alpha (pulmazyme)

d)

Ampetomizine

31.

N-acetyl-L-cysteneine (NAC) (Mucomyst)

a)

disrupts Disulfide bonds

b)

Breaks apart protein making up secretions

c)

Lyses DNA debris associated with thick pulmonary secretions of cystic fibrosis patient

32.

Proteolytics

a)

Breaks apart proteins making up secretions

b)

Disrupts disqualified bonds

33.

Dornase Alpha (Pulmozyme)

a)

Lyses DNA debris associated with thick pulmonary secretions of cystic fibrosis patient

b)

Breaks apart protein making up secretions

c)

Distrupts disqualification bonds

34.

Is dornase alpha (pulmozyme) only for CF patients?

a)

True

b)

False

35.

Dornase alpha ____ viscosity & adhesives of infected sputum

a)

Decrease

b)

Increase

36.

Dornase Alpha cleaves DNA in sputum

a)

True

b)

False

37.

Dornase alpha ___ the risk of bacterial infection

a)

Lowers

b)

heightens

38.

Contraindications of Dornase alpha (Pulmozyme) :

a)

Patients with hypersensitivity to Dornase alpha

b)

Patients with Chinese hamster ovary cell products

c)

Patients with liver injuries

39.

Should patients with CF continue other therapies with Dornase Alpha?

a)

True

b)

False

40.

Should other aerosol medications be mixed in the same SVN with pulmazyme?

a)

True

b)

False

41.

Most common side effects of Dornase Alpha

a)

Pharyngitis

b)

Laryngitis

c)

Voice alteration

d)

Rash

42.

N-acetyl-L-cysteneine (NAC) (Mucomyst) is an antioxidant

a)

True

b)

False

43.

N-acetyl-L-cysteneine (NAC) (Mucomyst)….

- You can get liver injury from acetaminophen overdose

a)

True

b)

False

44.

N-acetyl-L-cysteneine (NAC) (Mucomyst) is used as a mucolytic

a)

True

b)

False

45.

N-acetyl-L-cysteneine (NAC) (Mucomyst)

a)

Breaks apart sulfide bonds found in mucin

b)

Selectively cleaves dna in sputum

46.

Is N-acetyl-L-cysteneine (NAC) (Mucomyst) Recommended to improve airway clearance ?

a)

True

b)

False

47.

N-acetyl-L-cysteneine (NAC) (Mucomyst) may cause ___ amount of liquified secretions.

a)

High

b)

Low

48.

N-acetyl-L-cysteneine (NAC) (Mucomyst) may require

a)

Suction equipment

b)

Remaining with patient 10-15 min

c)

Adherents

49.

N-acetyl-L-cysteneine (NAC) (Mucomyst) may stimulate bronchospasm.

a)

True

b)

False

50.

You have to administer an aerosolized bronchodilator first before N-acetyl-L-cysteneine (NAC) (Mucomyst) to prevent bronchospasms

a)

True

b)

False

51.

Non respiratory uses of N-acetyl-L-cysteneine (NAC) (Mucomyst)

a)

Antidote for acetaminophen overdose when administered IV, Orally, or by Nasogastrical tube

b)

Prevents kidney damage occurring secondary to clearance of IV contrast dye material

c)

Cause increase in liquified secretions

52.

NAC is incompatible with inhaled

a)

Amphotericin B

b)

Tetracycline

c)

Erythromycin

d)

Ampicillin

53.

NAC has corrosive effects on metal parts

a)

True

b)

False

54.

NAC irritates mucosal membranes of oropharynx

a)

True

b)

False

55.

Non respiratory uses of NAC

a)

Effective antidote for acetaminophen overdose when administered IV, Orally, or by nasogastric tube

b)

Prevents kidney damage occurring secondary to clearance of IV contrast dye material

c)

Stimulates bronchospasm

d)

Require suction equipment

56.

Mukokinetic Agents improve movement of mucus

a)

True

b)

False

57.

Mucokinetic agents (B2 agonist)

a)

may increase ciliary beat frequency surfactant

b)

May improve cough clearance by improving expiratory air flow

c)

Prevents kidney damage

d)

May cause increase of liquified secretions

58.

B2 Adenergic agents Clinical effects

a)

Increases cyclic adenosine mono-phosphates

b)

Increases secretion production

c)

Decreases secretion production

59.

B2 adenergic agents has little mucocilary clearance effects in ______ & ______ patients

a)

COPD

b)

Bronchitis

c)

Aids

d)

Asthma

60.

Studies show modest but not long lasting benefit to _____ mucocilary clearance

a)

Increase

b)

Decrease

61.

Surfactant can _____ mucocilary clearance & _____ airway inflammation.

a)

Increase, decrease

b)

Decrease, increase

62.

Aerosol surfactant improves lung function and sputum clearance in patients with ______

a)

COPD

b)

Chronic bronchitis

c)

Asthma

63.

Ambroxol is approved in the US

a)

True

b)

False

64.

Ambroxol improves lung function and decreases exacerbations in patients with COPD

a)

True

b)

False

65.

Bronchorrhea

a)

Excess, thin, watery pulmonary secretions induced by expectorants

b)

Irritates mucosal membrane of oropharynx

66.

Expectorants _____ amount of fluid in respiratory tract

a)

Increases

b)

Decreases

67.

Expectorants stimulate mucus discharge with coughs

a)

True

b)

False

68.

Hypertonic saline for sputum induction

a)

Primary clinical application of bronchorretic agents in respiratory care

b)

Prevents kidney damage occurring secondary to clearance of IV contrast dye material

69.

Saturated solution of potassium iodide (SSKI) is administered in _____ forms.

a)

Oral

b)

Aerosolized

c)

Intravenous

70.

Saturated solution of potassium iodide (SSKI) is effective for stimulating airway fluid secretions

a)

True

b)

False

71.

Guaifenesine stimulates _____ in mucus production

a)

increase

b)

Decrease

72.

Guaifenesine maintains airway fluid layer

a)

True

b)

False

73.

Guaifenesine _____ viscosity & adhesiveness of secretions

a)

Increase

b)

Decrease

74.

Guaifenesine inhibits cough receptor sensitivity

a)

True

b)

False

75.

Guaifenesine: active ingredient in remedies

a)

mucinex

b)

Robitussin

c)

Advil

d)

Ibuprofen

76.

Guaifenesine improves ____, _____, & ______ with upper respiratory tract infection

a)

Cough

b)

Chest congestion

c)

Mucus thickness

d)

liver failure

77.

Guaifenesine: common side effects

a)

Headache

b)

Dizzy

c)

Nausea

d)

Vomiting

e)

Kidney stones

78.

Mannitol:

a)

Inhaled form being investigated for controlling pulmonary function in cystic fibrosis & bronchietasis patients

b)

Alters ph and disrupts stabilization of mucopolysaccharides

79.

Mannitol : changes physical properties of mucus associated with Cystic fibrosis & non cystic fibrosis bronchieactasis

a)

True

b)

False

80.

Sodium bicarbonate : alters Ph and distrupts stability of mucopolysaccharide strands

a)

True

b)

False

81.

Sodium bicarbonate : is demonstrated to dissolve sputum

a)

True

b)

False

82.

Sodium bicarbonate : useful in _____ irrigation for patients with artificial airways

a)

Tracheal

b)

Cough

c)

Conjunction

83.

Sodium bicarbonate : Contraindications include

a)

Severe sodium restricted diet

b)

Severe pre existing metabolic acidosis

c)

Vomiting

d)

Bronchitis

84.

Administer Sodium bicarbonate frequently to promote _____

a)

Musinex

b)

Mucokinetics

c)

Conjunction

85.

Mix Sodium bicarbonate at bedside before administering when used in conjunction with _____.

a)

Asthma pump

b)

Bronchodilator

c)

Acetaminophen

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