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WorksheetsDB014 6.1 & 6.2 Fact Check
Total questions: 40
Worksheet time: 40mins
A mutation is:
Permanent change in the DNA nucleotide sequence
Organism carrying mutated genes
Substance that can induce mutation
A mutant is:
Permanent change in the DNA nucleotide sequence
Organism carrying mutated genes
Substance that can induce mutation
The mutated DNA segment is TTCGCAAG. This is an example of ___ mutation.
Point mutation involves
deletion
insertion
duplication
changes in single base pair
A mutagen is:
Permanent change in the DNA nucleotide sequence
Organism carrying mutated genes
Substance that can induce mutation
Deletion
A
B
C
Substitution
A
B
C
Insertion
A
B
C
Normal erythrocyte
A
B
Sickle-shaped erythrocyte
A
B
In sickle cell anaemia, what happens to the haemoglobin and to the red blood cells?
Stiff, Crescent shaped
Stiff, Round
Flexible, Crescent shaped
Flexible, Round
Choose all TYPES of mutations
Gene
Chromosome
Spontaneous
Induced
Choose all CLASSES of mutations
Gene
Chromosome
Spontaneous
Induced
These are examples of ___ mutagens:
UV ray, gamma ray, alpha particle, X ray
Physical
Chemical
These are examples of ___ mutagens:
colchicine, ethidium bromide, alkylating agents
Physical
Chemical
Frameshift mutation is caused by base inversion.
True
False
Each amino acid has only one codon that can code for them
True
False
In sickle cell anaemia, amino acid ___ is swapped with a valine
Glycine
Glutamic acid
Glutamine
Methionine
Which one of the following is the most dangerous compared to the others?
Missense mutation
Nonsense mutation
Silent mutation
Frameshift mutation
Which one of the following can be considered as the safest compared to the others?
Missense mutation
Nonsense mutation
Silent mutation
Frameshift mutation
Failure of homologous chromosome / sister chromatid to separate properly during meiosis is known as (a) .
This mutation occurs in the presence of colchicine.
Induced mutation
Spontaneous mutation
Base substitution can cause the following mutations:
(Choose all that apply)
Missense mutation
Nonsense mutation
Silent mutation
Frameshift mutation
Base deletion can cause the following mutation(s):
(Choose all that apply)
Missense mutation
Nonsense mutation
Silent mutation
Frameshift mutation
Only one amino acid is changed in the polypeptide synthesised.
Missense mutation
Nonsense mutation
Silent mutation
Frameshift mutation
Codon reading frame is altered, changing most of the amino acids in the protein.
Missense mutation
Nonsense mutation
Silent mutation
Frameshift mutation
Codon is changed to a stop codon, causing premature translation of mRNA strand.
Missense mutation
Nonsense mutation
Silent mutation
Frameshift mutation
Change of nucleotide in a codon results in another codon that produce the same amino acid.
Missense mutation
Nonsense mutation
Silent mutation
Frameshift mutation
In sickle cell anaemia, codon (a) is changed to GUG, which codes for a valine, instead of a glutamic acid
In a person with Tay Sachs disease, frameshift mutation occurs in chromosome
11
13
15
16
Tay Sachs disease impacts the most on which of these cells?
Muscle cells
Nerve cells
Bone cells
Epidermis cells
Name ONE example of a stop codon.
(Do not include any spaces)
(a)
Nondisjunction during meiosis will produce gametes with abnormal chromosome numbers.
True
False
Ethidium bromide can (a) in between DNA bases, causing DNA molecule to stretch.
(Refer to the note used in the Edpuzzle)
