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WorksheetsPhysiology: Lecture 23
Total questions: 28
Worksheet time: 57mins
(a) is specific, learned after exposure, slow (but stored in memory) ACQUIRED
(a) is meditated by macromolecules found in ECF
EX: blood, ISF, breast milk
(B-lymphocyte)
passive immunity: aquires Ab from another organism
_____ _____ is mediated by activation of phagocytes, antigen presentation, and cytokine release in response to antigen.
(T-lymphocyte)
(a)
Which cell can splice and rearrange genes differently, producing antibodies with different specifities.
B-cell
T-cell
Alpha-cell
Choose all the correct immunoglobulin.
(TIP: Use the given acronym in slide 31)
IgM
IgA
IgD
IgG
IgE
When antigen binds to antibodies (Ab) this stimulates the b cell to divide and produce a(n)
Inhibit antibodies
Increase antibodies
Decrease antibodies
Destroy antibodies
Anti body types and their function:
*Study until you can explain each one.*
Look at the figures and graphs in the lectures. Become familiar with mechanisms.
Immature T cells “picks” a
T cell receptor (TCR)
B-cell
T Helper cell (TH)
T Killer cell (TK)
T cell migrates to the
Hypothalamus
Liver
Spleen
thymus
Interleukin (IL-2) differentiate (a) .
T-H cell or CD4, migrate to lymphatic tissue and help the
Stomach
Mucus
Virus
B-cells
Cytotoxic T cells or CD8, attack…
CHOOSE ALL THAT APPLY
Viruses
infected self cells
Cancer cells
Transplant rejection
T cell receptors and foreign antigens connect killer T cells or CD8, to… (note that the other would connect to CD4)
MHC 1
MHC 2
WHAT IS THE TERM?
Inflammation response to a non-pathogenic antigen (allergen)
(a)
Immediate hypersensitivity occurs in _____ and delayed hypersensitivity occurs after _____ _____.
(a)
WHAT IS THER TERM?
mediated by IgE and massive release of histamines
bronchoconstriction, vasodilation and shock
(a)
What is the correct order for first exposure to an allergen?
1) IgE secretion
2) stimulation of CD4 cell
3) stimulation of B cell
1-2-3
2-3-1
2-1-3
3-1-2
3-2-1
Juliana touches poison oak. What are the mechanisms for delayed hypersensitivity.Choose all that apply.
TK cell deactivates macrophages
TH cell secretes cytokines
TK cell do nothing
Allergen binds to TH cell
Lyse cells form
WHAT IS THE TERM?
Inhibits TH cell immune response and inflammation response
(a)
WHAT IS THE TERM?
Artificially activating the adaptive immune response
(a)
Does a vaccine create a memory cell without actually getting infected?
Yes
No
BOTH
Remember the 2 steps that vaccines take.
Which one helps our immune system identify a bacteria as nonself?
PAMPS
plasma membrane
Lipids
Amino acids
PAMP’S and Toxins can both be used for the production of what?
inclusion
Allergies
Viruses
Vaccines
For production of a Virus vaccine we would use…
Plasma membrane (found within the cell)
HPV (enclosing the virus genome)
Envelope proteins (spike)
Viral tegument (circling around the inside of the virus like beads)
A toxoid is given to a patient. They now have a single vaccine for a variety of bacteria and viruses.
True
False
Study and understand the COVID DRAWING and how it makes viral proteins to make more viruses.
