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THE ENDOCRINE SYSTEM

Total questions: 60

Worksheet time: 40mins

Name
Class
Date
1.

What is the function of endocrine gland?

a)

Secrete mucous

b)

Secrete hormone

c)

Secrete protein

d)

Secrete sweats

2.

What is the purpose of hormone in our body?

a)

To evoke a specific response in other cells

b)

To influence the rate of secretion of other cell

c)

To allow respiratory gas exchange

d)

To conduct nerve impulses receive from receptor to effector

3.

Endocrine glands consists of .. ?

a)

Secretory cells

b)

Extensive networks of capillary

c)

Ciliated cells

d)

Lobules

4.

Most hormone are synthesized from .. ?

a)

Amino acids

b)

Steroids

c)

Protein

d)

Lipid

5.

How does hormones evoke a specific response of targeted cell?

a)

Binds to a specific receptor and influence metabolic reactions

b)

Binds to cell membrane and influence metabolic reactions

c)

Binds to a specific receptor and open hormone channel

d)

Binds to cell membrane and open hormone channel

6.

Hormones are also known as ... ?

a)

Physical messenger

b)

Lipid messenger

c)

Amino acid messenger

d)

Chemical messenger

7.

Choose the CORRECT hormone functions.

a)

Regulation of growth and development

b)

Homeostatic control

c)

Control of reproductive system processes

d)

Synthesizing nerve impulses

8.

What is gland 2?

a)

Pineal

b)

Pituitary

c)

Thyroid

d)

Thymus

9.

What is gland 1?

a)

Pineal

b)

Pituitary

c)

Thyroid

d)

Thymus

10.

What is gland 3?

a)

Pineal

b)

Pituitary

c)

Thyroid

d)

Thymus

11.

What is gland 4?

a)

Pineal

b)

Pituitary

c)

Thyroid

d)

Thymus

12.

What is gland 5?

a)

Ovary

b)

Adrenal

c)

Testes

d)

Pancreatic

13.

What is gland 6?

a)

Ovary

b)

Adrenal

c)

Testes

d)

Pancreatic

14.

What is gland 7?

a)

Ovary

b)

Adrenal

c)

Testes

d)

Pancreatic

15.

What is gland 8?

a)

Ovary

b)

Adrenal

c)

Testes

d)

Pancreatic

16.

Hormones are transported throughout the body by ... ?

a)

Blood

b)

Lymph

c)

Saliva

d)

Gastric juice

17.

What is target cells?

a)

Cells with receptors for a given hormone

b)

Cells with targeted immune response

c)

Cells formatted to lyse

d)

Cells responsible to fight pathogens

18.

Receptors on target cells might be .. ?

a)

On cell surface

b)

Internal to cytoplasm

c)

Internal to nucleus

d)

In mitochondria

19.

There are two classes of hormone, which are .. ?

a)

Steroid

b)

Non steroid

c)

Protein

d)

Lipid

20.

Name ONE steroid hormone.

4 lines
21.

Name ONE non-steroid hormone.

4 lines
22.

Which of these is steroid hormone?

a)

Cortisol

b)

Epinephrine

c)

Insulin

d)

FSH

23.

Choose the CORRECT steroid hormone's characteristics.

a)

Lipid soluble

b)

Target cell's receptor in the cytoplasm/nucleus

c)

Hormone-receptor complex binds to DNA and stimulate reaction

d)

Move across membrane with the help of protein channel

24.

Choose the INCORRECT characteristic of amino acid/peptide/protein/non-steroid hormones.

a)

Bind with receptor and cause Ca channel open (Ca influx)

b)

target cell's receptor on cell membrane

c)

cAMP molecules activate reaction

d)

Diffuse into cell via protein channel

25.

What is calmodulin?

a)

When Ca binds with protein due to non-steroid hormone binds with cell surface receptor

b)

When Na binds with protein due to non-steroid hormone binds with cell surface receptor

c)

When Ca binds with protein due to steroid hormone binds with cell cytoplasm receptor

d)

When Na binds with protein due to steroid hormone binds with cell cytoplasm receptor

26.

cAMP is a .. ?

a)

Intracellular second messenger

b)

Extracellular second messenger

c)

Intracellular first messenger

d)

Extracellular first messenger

27.

Gland 2 is also known as .. ?

a)

The master gland

b)

The secondary gland

c)

The primary gland

d)

The ruler gland

28.

Choose the hormones synthesized by the posterior lobe of gland 2.

a)

Oxytocin

b)

Growth hormone

c)

Anti Diuretic Hormone

d)

FSH

29.

Gland 2 synthesize a hormone that controls the production & secretion of hormones by the adrenal cortex.

What is this hormone?

a)

Corticotropin

b)

Growth hormone

c)

Prolactin

d)

FSH

30.

Gland 2 synthesize a hormone that starts & maintains milk production in mammary glands.

Where in gland 2 does this hormone synthesized?

a)

Cortex

b)

Medulla

c)

Posterior

d)

Anterior

31.

TSH is a hormone synthesized at the anterior lobe of gland 2. What is the function of TSH?

a)

Stimulates production or secretion of thyroid hormones.

b)

Control reproductive function

c)

Controls growth & body development

d)

Retain water and together with aldosterone

32.

This is pituitary gland. Choose the CORRECT hormones that synthesized at the green zone of pituitary gland. (based on the picture)

a)

Prolactin

b)

Corticotropin

c)

Anti Diuretic Hormone

d)

Growth hormone

33.

How does elevated cortisol in blood affect the release of Corticotropin (ACTH) ?

a)

Cortisol released by adrenal that is stimulated by ACTH. High cortisol suppress the release of ACTH and CRH

b)

Cortisol released by adrenal that is stimulated by ACTH. High cortisol encourage the release of ACTH and CRH

c)

Cortisol released by adrenal that is stimulated by ACTH. High cortisol stimulate the release of ACTH and CRH

d)

Cortisol released by adrenal that is stimulated by ACTH. High cortisol restore the release of ACTH and CRH

34.

When someone suffer from hypoglycemia, which hormone stimulated and increased?

a)

hGH

b)

GHIH

c)

GHRH

d)

IGF

35.

When someone suffer from dehydration and hypotension, which hormone is stimulated?

a)

GH

b)

ADH

c)

ACTH

d)

PRL

36.

Hypotension stimulates ... from hypothalamus and later activate the release of ... from posterior lobe of pituitary gland. Water retention increases, sweat glands decrease water loss and arterioles constrict. Blood pressure returns normal.

a)

Osmoreceptor, ADH

b)

ACTH, ADH

c)

GHIH, osmoreceptor

d)

GHRH, ACTH

37.

Gland 5 can be divided into two layers, which are .. ?

a)

Medulla

b)

Anterior

c)

Posterior

d)

Cortex

38.

Medulla of gland 5 produce .. ?

a)

NE

b)

Aldosterone

c)

Cortisol

d)

E

39.

Cortex of gland 5 produce .. ?

a)

NE

b)

Aldosterone

c)

Cortisol

d)

Androgen

40.

Medulla of gland 5 is controlled by .. ?

a)

Sympathetic nerve

b)

Parasympathetic nerve

c)

Cranial nerve

d)

Spinal nerve

41.

What are the roles of neurotransmitter produced by adrenal medulla?

a)

Vasodilation of vessels to brain, muscles, heart

b)

Contract smooth muscle strongly

c)

Speed up heart rate

d)

Increase mental alertness

e)

Decrease glucose level

42.

Which cells of gland 6 produce hormone?

a)

Islets of Langerhans

b)

Endothelial cell

c)

Epithelial cell

d)

Smooth muscle cell

43.

Alpha cells of Langerhans secrete .. ?

a)

Glucagon

b)

Insulin

c)

Glucose

d)

Cortisol

44.

Beta cells of Langerhans secrete .. ?

a)

Glucagon

b)

Insulin

c)

Glucose

d)

Cortisol

45.

How does insulin lowers blood glucose level?

a)

Stimulate target cells to take up glucose

b)

Stimulate target cells to store glucose as glycogen

c)

Stimulate target cells to convert glycogen to glucose

d)

Stimulate the conversion of amino acid to glucose

46.

Secretion of insulin and glucagon by alpha and beta cells of Langerhans is controlled directly by .. ?

a)

Concentration of blood glucose

b)

Concentration of blood pressure

c)

Concentration of oxygen

d)

Concentration of carbon dioxide

47.

When someone suffers from low metabolic rate (or low T3&T4), what happens?

a)

Stimulate release of TRH → stimulate TSH → stimulate thyroid follicular cell

b)

T3 inhibits TRH and TSH

c)

Stimulate thyroid follicular cell → stimulate TSH → stimulate release of TRH

d)

T3 stimulate Ca influx

48.

What are the roles of thyroid hormone?

a)

Increase basal metabolic rate

b)

Increase body temperature

c)

Stimulate protein synthesis

d)

Lower the use of glucose for ATP production

49.

What does parathyroid hormone do?

a)

Promote release of Ca

b)

Slow the loss of Ca in urine

c)

Increase blood Ca level

d)

Inhibits osteoclasts

50.

What are the hormones synthesize by kidneys?

a)

EPO

b)

Renin

c)

Angiotensin

d)

Aldosterone

51.

Aldosterone is secreted by adrenal gland when .. ?

a)

Angiotensin 2 stimulate

b)

Low blood pressure

c)

High blood Na level

d)

Angiotensinogen stimulate

52.

When someone suffers from hypertension, the heart release .. ?

a)

ANP

b)

ADH

c)

PRL

d)

FSH

53.

Gland 7 produce .. ?

a)

Estrogen

b)

Progesterone

c)

Testosterone

d)

FSH

54.

What are the functions of progesterone in female reproductive system?

a)

Prepares the lining of the uterus for implantation of a fertilized egg

b)

Prepare the mammary glands to secrete milk

c)

Controls the development of female sex characteristics

d)

Controls the ovulation of ovarian cycle

55.

Gland 8 produce .. ?

a)

Estrogen

b)

Progesterone

c)

Testosterone

d)

FSH

56.

The gastrointestinal tract produce ... hormone.

a)

Cholecystokinin

b)

Cholesterol

c)

Cortisol

d)

Aldosterone

57.

What are the roles of cholecystokinin?

a)

Controls peristalsis

b)

Increase gallbladder contraction

c)

Produce gastric juice

d)

Produce bile salts

58.

The leptin hormone is produced by .. ?

a)

Adipose tissue

b)

Adrenal gland

c)

Pancreas

d)

Kidney

59.

What is the function of leptin hormone?

a)

Controls sleepiness

b)

Controls appetite

c)

Controls blood pressure

d)

Controls emotion

60.

The pineal gland produce .. ?

a)

Melatonin

b)

Cortisol

c)

Androgen

d)

Epinephrine