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Worksheets

Microbial Genetics

Total questions: 58

Worksheet time: 29mins

Name
Class
Date
1.

Which of the following characteristics do animals, fungi, and protozoa have in common?

a)

They obtain their energy from light.

b)

They obtain their energy and carbon atoms from chemicals.

c)

They obtain their carbon from inorganic compounds.

d)

They obtain their carbon from carbon dioxide.

2.

Which of the following processes does not involve bacteriophages?

a)

lysogenic conversion

b)

transformation

c)

transduction

d)

lytic cycle

3.

In transduction, bacteria acquire new genetic information in the form of:

a)

bacterial genes

b)

naked DNA

c)

R-factors

d)

viral genes

4.

The process whereby naked DNA is absorbed into a bacterial cell is called:

a)

transcription

b)

transduction

c)

transformation

d)

translation

5.

The process by which a nontoxigenic Corynebacterium diphtheriae cell is changed into a toxigenic cell is called:

a)

transformation

b)

transduction

c)

lysogenic conversion

d)

conjugation

6.

The physical characteristics of an organism make up the organism’s:

a)

Phenotype

b)

Genotype

7.

An organism detoxifies H2O2. This statement describes the organism’s:

a)

Phenotype

b)

Genotype

8.

An organism has a gene that codes for catalase. This statement describes the organism’s:

a)

Genotype

b)

Phenotype

9.

What is a gene?

a)

A collection of codons

b)

A segment of DNA that codes for a specific product

c)

A segment of DNA with a specific nucleotide sequence

10.

Prokaryotic and eukaryotic chromosomes are different in that:

a)

Eukaryotic chromosomes lack introns

b)

Prokaryotic chromosomes are circular

c)

Prokaryotic chromosomes consist of chromosomal RNA

d)

Prokaryotic chromosomes are single stranded

11.

What is the function of cAMP in regulation of the lac operon?

a)

activates an activator protein

b)

activates a repressor protein

c)

inactivates an activator protein

d)

inactivates a repressor protein

12.

Which of the following statements is FALSE?

a)

The lagging strand of DNA is started by an RNA primer.

b)

DNA polymerase joins nucleotides in one direction (5' to 3') only.

c)

DNA replication proceeds in one direction around the bacterial chromosome.

d)

The leading strand of DNA is made continuously.

13.

In prokaryotes, two replication forks arise at the origin of replication and move in opposite directions until:

a)

They reach the ends of the chromosome

b)

They meet

c)

They reach the stop codon

d)

Prokaryotes only have one replication fork

14.

In transcription:

a)

DNA polymerase replicates DNA

b)

Ribosomes make amino acids

c)

RNA polymerase makes tRNA

d)

DNA makes mRNA

15.

In translation:

a)

DNA polymerase replicates DNA

b)

Ribosomes make amino acids

c)

Ribosomes read mRNA and make protein

d)

RNA polymerase makes mRNA

16.

In replication:

a)

DNA polymerase replicates DNA

b)

Ribosomes make amino acids

c)

Ribosomes read mRNA and make protein

d)

RNA polymerase makes mRNA

17.

Synthesis of enzymes coded for by genes that are part of the lac operon:

a)

Is inhibited by galactose

b)

Is stimulated by binding of glucose to the repressor

c)

Is not turned on unless lactose is present

d)

Requires a co-repressor

18.

A frameshift mutation is the result of:

a)

The deletion of the promoter

b)

The deletion of the operator

c)

The substitution of one base for another

d)

The addition or deletion of a base or bases to a strand of DNA

19.

Mutations may be caused by:

a)

Chemicals

b)

Radiation

c)

Spontaneous changes in the base sequence without mutagens

d)

All of the these

20.

Enzyme that splits lactose:

a)

Transacetylase

b)

Allolactose

c)

Beta-galactosidase

d)

Lac permease

21.

An enzyme produced in response to the presence of a substrate is called a(n):

a)

inducible enzyme

b)

restriction enzyme

c)

operator

d)

repressible enzyme

22.

Which of the following cells incorporates the F factor into their genome and is responsible for multi-antibiotic-resistant bacteria?

a)

Bacteriophage

b)

Hfr

c)

F-

d)

F+

23.

Mutations are always harmful to an organism.

a)

True

b)

False

24.

Mutations are changes in the base sequence of a DNA molecule.

a)

True

b)

False

25.

A point mutation will always change the product coded for by the gene in which the mutation occurs.

a)

True

b)

False

26.

A frameshift mutation will always change the product coded for by the gene in which the mutation occurs.

a)

True

b)

False

27.

In prokaryotes, transcription and translation can occur simultaneously.

a)

True

b)

False

28.

Supercoiling in bacteria is accomplished using histones.

a)

True

b)

False

29.

Eukaryotes tend to have multiple origins of replication; prokaryotes have one .

a)

True

b)

False

30.

Nucleotides are separated via the process of:

a)

glycolysis

b)

proteolysis

c)

lipolysis

d)

hydrolysis

31.

DNA replication occurs during the ____ phase of Binary Fission.

a)

R

b)

D

c)

S

d)

I

32.

Most DNA replication occurs during the ____ phase of microbial growth.

a)

LAG

b)

Death

c)

Stationary

d)

LOG

33.

Reading a strand of DNA/mRNA always proceeds in what direction?

a)

left to right

b)

5' -> 3'

c)

3' -> 5'

d)

right to left

34.

Prokaryotes have spliceosomes that cut out introns.

a)

True

b)

False

35.

Eukaryotes have spliceosomes that cut out introns.

a)

True

b)

False

36.

The genetic code involves degeneracy, meaning:

a)

amino acids decay quickly

b)

each codon is coded for by several amino acids

c)

each amino acid is coded by several codons

d)

DNA is an alcoholic

37.

The start codon in euks and proks is _______.

a)

UAA

b)

AUG

c)

UAG

d)

UUU

38.

Translation forms ___________ bonds between amino acids.

a)

glycosidic

b)

hydrogen

c)

peptide

d)

ionic

39.

____________ is responsible for keeping excess lactose inside the bacterial cell (against the concentration gradient).

a)

transacetylase

b)

beta-lactamase

c)

lac permease

d)

beta-galactosidase

40.

E. coli contamination is found in yogurt. Will it produce beta-galactosidase?

a)

Yes

b)

No

41.

E. coli contamination is found in ground beef. Will it produce beta-galactosidase?

a)

Yes

b)

No

42.

Repressors and inducers bind to the _________ site of the operon.

a)

promotor

b)

operator

43.

Which will a bacterium eat first?

a)

Glucose

b)

Lactose

c)

Starch

d)

Mannitol

44.

In order for a cell to genetically recombine, it must be ______________ - in a n optimal physiological state.

a)

altered

b)

a bacillus

c)

competent

d)

geneless

45.

When an F+ cell donates to an F- cell, a ____ cell results.

a)

F+

b)

F-

c)

New

d)

HFR

46.

DNA polymerase:

a)

unzips the double helix

b)

relaxes the DNA strands

c)

keeps DNA strands separated during replication

d)

adds nucleotides/ proofreads DNA

e)

binds to promoter and initiates transcription

47.

Topoisomerase/Gyrase:

a)

unzips the double helix

b)

relaxes the DNA strands

c)

keeps DNA strands separated during replication

d)

adds nucleotides/ proofreads DNA

e)

binds to promoter and initiates transcription

48.

Helicase:

a)

unzips the double helix

b)

relaxes the DNA strands

c)

keeps DNA strands separated during replication

d)

adds nucleotides/ proofreads DNA

e)

binds to promoter and initiates transcription

49.

Single-stranded-binding protein:

a)

unzips the double helix

b)

relaxes the DNA strands

c)

keeps DNA strands separated during replication

d)

adds nucleotides/ proofreads DNA

e)

binds to promoter and initiates transcription

50.

Primase:

a)

separates pyrimidine (T/C) dimers

b)

joins Okazaki fragments on lagging strand

c)

keeps DNA strands separated during replication

d)

synthesizes primer on the lagging strand for DNA polymerase binding

e)

binds to promoter and initiates transcription

51.

Ligase:

a)

separates pyrimidine (T/C) dimers

b)

joins Okazaki fragments on lagging strand

c)

keeps DNA strands separated during replication

d)

synthesizes primer on the lagging strand for DNA polymerase binding

e)

binds to promoter and initiates transcription

52.

Photolyase:

a)

separates pyrimidine (T/C) dimers

b)

joins Okazaki fragments on lagging strand

c)

keeps DNA strands separated during replication

d)

synthesizes primer on the lagging strand for DNA polymerase binding

e)

binds to promoter and initiates transcription

53.

RNA polymerase:

a)

separates pyrimidine (T/C) dimers

b)

joins Okazaki fragments on lagging strand

c)

keeps DNA strands separated during replication

d)

synthesizes primer on the lagging strand for DNA polymerase binding

e)

binds to promoter and initiates transcription

54.

When a sex pilus or mating bridge is used to transfer genes between organisms:

a)

transduction

b)

conjugation

c)

transposon

d)

bacteriophage

55.

Set of operator and promotor sites and the structural genes they control:

a)

operon

b)

transducer

c)

transformer

d)

transposer

56.

Virus that infects bacteria:

a)

transposer

b)

transducer

c)

bacteriophage

d)

tranposer

57.

Circular, self-replicating, extrachromosomal DNA

a)

operon

b)

plasmid

c)

transformer

d)

transposer

58.

Promoter:

a)

initiates transcription of structural genes on an operon

b)

controls transcription of structural genes on an operon

c)

when two chromosomes exchange information

d)

passing genetic info to cells in the same generation