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WorksheetsEndocrinology
Total questions: 10
Worksheet time: 5mins
A 50 year old man presents with gynaecomastia, galactorrhoea, loss of body and pubic hair and reduced libido. Visual field testing reveals a bitemporal hemianopia. A prolactin level is checked and the result is 6440 mU/L.
What is the most appropriate treatment?
Levothyroxine
Bromocriptine
Domperidone
A 28 year old woman attends your clinic with a 3 month history of absent periods, production of milk from her breasts and a reduced sex drive. She confirms that she has done a pregnancy test and it is negative.
What is the MOST LIKELY diagnosis?
Acromegaly
Cushing's Syndrome
Prolactinoma
PCOS
Which one of the following is a known cause of hypercalcaemia?
Marfan syndrome
Excess fluid intake
Bendroflumethiazide
A 66 year old woman attends your clinic requesting a routine blood test. Her blood pressure today is 114/78 mmHg, pulse 84/min and she is apyrexial. You arrange some blood tests which show the following abnormality:
Corrected calcium: 2.9 mmol/L (Normal: 2.2 to 2.7 mmol/L)
Which ONE of the following tests is most useful in investigating the cause of the raised serum calcium levels? Select ONE option only.
TFTs
Vitamin D
Phosphate
Parathyroid hormone
A 51 year old male is found to have a raised calcium on his recent blood tests, he is asymptomatic at the moment, but you wonder if it is due to a recent medication he started.
Which ONE of the following medications can cause hypercalcaemia?
Lithium
Metformin
Ramipril
A 42 year old lady with a background of Addision's disease attends your clinic with a 5 day history of fever, dysuria and frequency. A urine dipstick shows leucocytes and nitrites. You decided to prescribe antibiotics for a suspected UTI.
With regards to this patient's Addision treatment, what should she be advised?
seek specialist advice
add 5-10mg hydrocortisone to normal regimen
double normal dose of glucocorticoid until recovered
A 34 year old male is seen in ED, with increased lethargy, nausea, vomiting, non specific abdominal pain and dizziness. His past medical history includes type 1 diabetes, and irritable bowel syndrome. On examination his BM's are normal, there are no ketones in his urine, and you note a significant postural hypotension. You begin to suspect underlying Addison's disease.
Which ONE of the following electrolyte abnormalities is MOST LIKELY to be seen in Addison's disease?
Hypokalaemia & Hypernatraemia
Hyponatraemia & Hyperkalaemia
Normal Sodium and Potassium
A 19 year old female with suspected Addison's disease is referred to the endocrine clinic for further assessment.
Which ONE of the following choices best describes the Adrenocorticotrophic Hormone Stimulation (Synacthen) test?
Cortisol levels before and 30min after synthetic ACTH
Cortisol levels before and 90min after synthetic ACTH
Cortisol levels before and 180min after synthetic ACTH
You review a patient with suspected Addison’s disease.
Which biochemical feature would you NOT expect to see in this condition?
High potassium
low sodium
high ACTH
low renin level
A 50 year old male is diagnosed with Cushing's disease after being reviewed in the endocrinology clinic.
Which ONE of the following is considered the MOST COMMON cause of Cushing's disease?
Pancreatic neuroendocrine tumours
pituitary adenoma
small-cell carcinoma of the lung
