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WorksheetsClin chem Cardiac Markers
Total questions: 51
Worksheet time: 26mins
AMI stands for ?
Acute Myocardiac Infarction
Acute Myocardial Infraction
Acute Myocardial Infarction
None
What are the 3 Creatinine Kinase Isoenzymes?
CKBB, CKMB, CKMM
CKMB,CKBM,CKNN
CKBM, CKMB, CKMM
None
Is troponin an Enzyme?
Yes it is
No it is not
Maybe
What Creatinine Kinase Isoenzyme is for the brain and prostate?
CKBB
CKMB
CKMM
LDH
What Creatinine Kinase Isoenzyme is for the Heart?
CKBB
CKMB
CKMM
LDH
What Creatinine Kinase Isoenzyme is for the Skeletal Muscle ?
CKBB
CKMB
CKMM
LDH
LDH stands for?
Lactate Dihydrogenase
Lactate Dehydrogenase
Lactic Dehydrogenase
Which LD Isoenzymes are a primary concern in diagnosis of AMI?
LD 1 & LD 2
LD 1 & LD 3
LD 3 & LD 4
LD 1 & LD 4
LD 2 & LD 4
Which troponin has a calcium binding subunit, in both cardiac and skeletal muscle, and not specific for cardiac issues?
Troponin A
Troponin T
Troponin C
Troponin I
Which troponin is produced during fetal development in skeletal muscle, but not in skeletal muscle of adults?
Troponin A
Troponin T
Troponin C
Troponin I
What is the Rise of AMI - Acute Myocardial Infection?
Within a few hours
More then an Hour
Within 30 minutes
After 2 hours of ingestion
What is the peak of AMI - Acute Myocardial Infection?
Within a few hours
More then an 2 hours
Within 90 minutes
Within 2 days
How long does an AMI - Acute Myocardial Infarction stays elevated?
9 to 10 days
5 to 10 days
8 to 10 days
7 to 10 days
What troponin binds to actin and tropomyosin, which is present only in the cardiac muscle and therefore is specific for heart cellular damage?
Troponin A
Troponin T
Troponin C
Troponin I
What are the 7 signs of Pathological Conditions of the Heart?
Dyspnea, Chest pain, Palpitation, Syncope, Edema, Cyanosis, Fatigue
Dyspnea, Chest pain, Fever, Syncope, Edema, Cyanosis, Fatigue
Dyspnea, Chest pain, Palpitation, Syncope, Edema, Cyanosis, Vomiting
Dyspnea, Chest pain, Palpitation, Dehydration, Edema, Cyanosis, Fatigue
What are the Traditional Laboratory Diagnosis for Heart disease AMI- Acute Myocardial Infarction?
AST, CK, LD/CK and LD isoenzymes, Myoglobin
ALT, CK, LDH and Myoglobin
AST, ALT, LDH and Myoglobin
All of the Abone
What are the Current Laboratory Diagnosis for Heart disease AMI- Acute Myocardial Infarction?
AST, CK, LD/CK and LD isoenzymes, Myoglobin
ALT, CK, LDH and Myoglobin
CK, CKBB, & Troponin C
CK and CKMB, Troponin
LDH is present in many areas of the body except for ?
Red Blood Cells
Liver
Heart
Pancreas
Brain
List in order the amount of LDH isoenzymes present from least to greatest.
LD = 1,2,3,4,5
LD = 2,1,3,5,4
LD = 2,1,3,4,5
LD = 5,4,3,2,1
What Lactate Dehydrogenase Isoenzymes are found in the Heart and Red blood cells?
LD 1 and LD 2
LD 2 and LD 3
LD 3 and LD 4
LD 5 and LD1
LD 1 and LD 3
Where can LD 3 be found inside our body?
The liver, lung, lymph nodes, pancreas, and platelets. (elevated in mono, PE, pancreatic or pulmonary issues.
The spleen, lung, lymph nodes, pancreas, and platelets. (elevated in mono, PE, pancreatic or pulmonary issues.
The heart, liver, lung, lymph nodes, pancreas, and platelets. (elevated in mono, PE, pancreatic or pulmonary issues.
Just the Kidneys and Liver
Why do men have a higher Creatinine Kinase levels than women?
Because of genetics
Because of the reproductive organs
Because of the muscles
Because of the hormones
What are the causes of increased levels of Creatinine Kinase?
Strenuous exercise and Intradermal Injections
Vigorous exercise and intramuscular injections
Strenuous exercise and Intramuscular injections
Vigorous exercise and intradermal injections
What are the specimens used for CKMB?
Serum or Plasma with no hemolyisis
Serum or Plasma with slight hemolysis
Plasma with no Clott
Serum with no Hemolysis
What is the recommended specimen used for CKMB?
Serum or Plasma with no hemolyisis
Serum or Plasma with slight hemolysis
Plasma with no Clott
Serum with no Hemolysis
BNP stands for?
(a)
This are released on the ventricular stretch or stress to myocytes?
BNP and pro-BNP
Non BNP and pro-BNP
BNP only
Pro-BNP only
It has a half-life of 20 minutes-quick snapshot of myocardial infarction.
CK
CKMB
CKBB
BNP
Pro-BNP
What are the 3 Layers of the Heart? IN order.
Epicardium, Myocardium & Endocardium
Endocardium, Myocardium & Epicardium
Myocardium, Endocardium, & Epicardium
Myocardium, Epicardium, & Endocardium
The preferred cardiac marker in testing.
(a)
Troponins have a ________ and _________ for myocardial damage.
Specificity, Sensitivity
Sensitivity, Specificity
The two cardiac Laboratory test most likely to be ordered when the physician suspects a MI is?
CK-CKMB and AST
CK-CKBB and AST
CK-CKMM and AST
CK-CKMB, LDH and AST
The cardiac Specific laboratory test most likely to be ordered as a follow-up test.
Creatinine kinase
LDH
Troponin T
BNP and Pro-BNP
It is Clinically useful for early release within 1 to 4 hours from damaged muscle. Its Half-life peaks at 5 -12 hours and will be normal within 24 hours.
Cardiac Troponin
Myoglobin
Protein
Creatinine Kinase
It is an acute phase protein produced by the liver in response to injury, infection and inflammation.
Troponin
Creatinine
Myoglobin
Albumin
High Sensitivity C-reactive protein
Useful in its high predictive value for coronary artery disease due to atherosclerosis.
Troponin
Creatinine
Myoglobin
Albumin
High Sensitivity C-reactive protein
An elevated levels linked to early arterial inflammation and can cause damage to arterial walls that precedes formation of plaque.
Troponin
Myoglobin
Homocysteine
Myoglobin
Cardiac Markers Rise, Peak, & Normal
For Total Creatinine Kinase
4-6 hrs, 18-24 hrs, & 2-3 days
4-5 hrs, 18-24 hrs, & 2 days
4-6 hrs, 16-24 hrs, & 2 days
4-5 hrs, 16-24 hrs, 2-3 days
Cardiac Markers Rise, Peak, & Normal
For CK-MB
4-6 hrs, 18-24 hrs, & 2-3 days
4-5 hrs, 18-24 hrs, & 2 days
4-6 hrs, 16-24 hrs, & 2 days
4-5 hrs, 16-24 hrs, 2-3 days
Cardiac Markers Rise, Peak, & Normal
For Myoglobin
1-4 hrs, 5-12 hrs, & 24 hrs
2-4 hrs, 6-12 hrs, & 24 hrs
1-4 hrs, 8-12 hrs, & 24 hrs
2-4 hrs, 8-12 hrs, & 24 hrs
Cardiac Markers Rise, Peak, & Normal
For Troponin
4-6 hrs, 12-18 hrs, & 24 hrs
6-8 hrs, 10-12 hrs, & 6 days
6-8 hrs, 10-12 hrs, & 24 hrs
4-6 hr 12-18 hrs 6 days
Cardiac Markers Rise, Peak, & Normal
For AST
6-8 hr 24 hrs 5 days
7-8 hr 24 hrs 5 days
6-8 hr 24 hrs 6 days
7-8 hr 24 hrs 6 days
Cardiac Markers Rise, Peak, & Normal
For LDH
24-48 hr 4-6 days 8-10 days
36-48 hr 4-6 days 8-10 days
24-48 hr 2-3 days 8-10 days
36-48 hr 2-3 days 8-10 days
A group of disorders of the heart and blood vessels is called?
Constipation Disorder
Cardiomuscular Disease
Cardiovascular Disase
Crohn's Disease
It is the narrowing or hardening of the arteries due to formation of plaque
Arthritis
Atherosclerosis
Congenital Disease
Rheumatic Heart Disease
What are the process of Plaque Formation? (1 or more Answers might be plausible)
An increased LDL will deposit in the tunica intima and becomes oxidized
There is an increased LDL will deposit in the tunica media and becomes oxidized
The oxidized LDL activates endothelial cells and will express receptors for WBCs
An oxidized LDL activates endothelial cells and will deactivate receptors for WBCs
Choose the correct answer which describes; Coronary Heart Disease.
A disease of the blood vessels supplying the heart muscle.
Poor blood flow to the heart because of plaque formation.
Manifests as myocardial infarction, angina, heart failure and sudden cardiac death
Disease of the blood vessels supplying the brain
.Manifests as stroke or transient ischemic attacks.
Manifests as either aortic aneurysm or aortic dissection.
Disease of blood vessels supplying the arms and legs
.Manifests by intermittent claudication.
Permanent damage to heart muscle, mainly the valves, from the inflammation and scarring caused by rheumatic fever.
Choose the correct answer which describes; Cerebrovascular Disease
A disease of the blood vessels supplying the heart muscle.
Poor blood flow to the heart because of plaque formation.
Manifests as myocardial infarction, angina, heart failure and sudden cardiac death
Disease of the blood vessels supplying the brain
.Manifests as stroke or transient ischemic attacks.
Manifests as either aortic aneurysm or aortic dissection.
Disease of blood vessels supplying the arms and legs
.Manifests by intermittent claudication.
Permanent damage to heart muscle, mainly the valves, from the inflammation and scarring caused by rheumatic fever.
Choose the correct answer which describes; Aortic Atherosclerosis
A disease of the blood vessels supplying the heart muscle.
Poor blood flow to the heart because of plaque formation.
Manifests as myocardial infarction, angina, heart failure and sudden cardiac death
Disease of the blood vessels supplying the brain
.Manifests as stroke or transient ischemic attacks.
Manifests as either aortic aneurysm or aortic dissection.
Disease of blood vessels supplying the arms and legs
.Manifests by intermittent claudication.
Permanent damage to heart muscle, mainly the valves, from the inflammation and scarring caused by rheumatic fever.
Choose the correct answer which describes; Peripheral Artery Disease
A disease of the blood vessels supplying the heart muscle.
Poor blood flow to the heart because of plaque formation.
Manifests as myocardial infarction, angina, heart failure and sudden cardiac death
Disease of the blood vessels supplying the brain
.Manifests as stroke or transient ischemic attacks.
Manifests as either aortic aneurysm or aortic dissection.
Disease of blood vessels supplying the arms and legs
.Manifests by intermittent claudication.
Permanent damage to heart muscle, mainly the valves, from the inflammation and scarring caused by rheumatic fever.
Choose the correct answer which describes; Rheumatic Heart Disease
A disease of the blood vessels supplying the heart muscle.
Poor blood flow to the heart because of plaque formation.
Manifests as myocardial infarction, angina, heart failure and sudden cardiac death
Disease of the blood vessels supplying the brain
.Manifests as stroke or transient ischemic attacks.
Manifests as either aortic aneurysm or aortic dissection.
Disease of blood vessels supplying the arms and legs
.Manifests by intermittent claudication.
Permanent damage to heart muscle, mainly the valves, from the inflammation and scarring caused by rheumatic fever.
