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WorksheetsABO blood groups
Total questions: 27
Worksheet time: 14mins
Groups A, B , and O discovered by ____ in 1900.
Karl Landsteiner
Descastello & Sturli
Weiner
Blundell
Whose rule stated that "normal, healthy individuals possess ABO antibodies to the ABO antigens absent from their red blood cells'?
Karl Landsteiner
Descastello & Sturli
Weiner
Blundell
The A blood type is the H antigen and ___
N-acetylgalactosamine
D-galactose
no additional sugar attached
recessive "h"
The B blood type is the H antigen and ___
N-acetylgalactosamine
D-galactose
no additional sugar attached
recessive "h"
The O blood type is the H antigen and ___
N-acetylgalactosamine
D-galactose
no additional sugar attached
recessive "h"
Just L-fucose with no terminal sugar belongs to the _____ antigen
A
B
O
H
In which fluid will you find H, A, and B antigens for non-secretors?
blood
tears
milk
bile
All Secreter genotype(s)
Sese
SeSe and
Sese
sese
All non-secreter genotype(s)
Sese
SeSe and
Sese
sese
Group ‘O’ secretors have ______ in their secretions
H antigen
A and H antigen
B and H antigen
A, B, and H antigen
Group ‘B’ secretors have ______ in their secretions
H antigen
A and H antigen
B and H antigen
A, B, and H antigen
Group ‘AB’ secretors have ______ in their secretions
H antigen
A and H antigen
B and H antigen
A, B, and H antigen
Which is false of ABO antigen production?
A and B antigen development begins 5-6 in utero
adult levels are reached 2-4 years of age
neonates are born with fully functional ABO antigens on their RBCs
Level is about 50% at birth
What is the order of decreasing amounts of H antigen concentration in ABO phenotypes?
O > A2 > B > A2B > A1 > A1B
O > B > A > AB
O > A1 > B > A1B > A2 > A2B
O > A1 > B > A2B > A2 > A1B
What are the two main subgroup of A blood?
A1
A2
A1 lectin
A3
Approximately ____of Group A individuals are A1
____are A2 or a weaker subgroup
Anti-A1 can be found in _____ of Group A2 individuals
80 %
20%
1%-8%
20 %
80 %
<5%
50 %
50%
2%
45 %
45%
10%
Which is true of A subgroups?
strong agglutination with commercial anti-A is key in recognizing subgroups
monoclonal antibodies are designed to enhance the detection of subgroups
shows mixed-field agglutination with anti-A or anti-A,B antisera
they do NOT affect reverse blood typing
Which blood phenotype produce anti-H/A/B and their inheritance is homozygous hh (symbol is Oh)?
A
AB
O
Bombay
genes cause antibody production similar to the way they cause certain antigens to develop on red cells
Genetic theory
Environmental theory
biochemical structures in the environment similar to A and B antigens stimulate ABO antibody production after birth
Genetic theory
Environmental theory
Which is true of Group O individuals, but false of AB?
primarily IgG ABO antibodies
primarily IgM with small amounts of IgG
ABO antibodies
primarily IgG ABO antigens
primarily IgM with small amounts of IgG
ABO antigens
Which correct about ABO antibodies?
React best at room temperature or below during the immediate spin phase
Do require enhancement (Saline agglutinating antibodies)
Do require incubation
at 37 degrees
React best 1-3 hours after centrifugation
Testing unknown patient red cells for ABO antigens using known anti-A and anti-B antisera
FORWARD GROUPING
REVERSE GROUPING
Testing the serum of the patient for ABO antibodies using known A1 and B cells
FORWARD GROUPING
REVERSE GROUPING
How do you find the ABO type of a neonate?
forward grouping only on cord blood
reverse grouping only mother's plasma
forward grouping only capiliary blood
reverse grouping on neonate plasma
Universal RBC donor
O
A
B
AB
Universal plasma donor
O
A
B
AB
