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Biotechnology product

Total questions: 21

Worksheet time: 21mins

Name
Class
Date
1.

What are the types of biotechnology products?

(a)  

2.

Luxturna is an example of ___ biotechnology product

a)

Cells

b)

Proteins

c)

Genes

3.

SELECT ALL the genes biotechnology products

a)

Pfizer

b)

Johnson & Johnson

c)

Talimogene laherparepvec

d)

Alemtuzumab

e)

Sipuleucel-T

4.

All stem-cell therapy products are approved to be used by FDA

a)

True

b)

False

5.

Sipuleucel-T is a cell therapy product

a)

True

b)

False

6.

SELECT ALL the natural protein products

a)

Insulin

b)

Factor VIII

c)

Cytokines

d)

Monoclonal antibodies

e)

Moderna

7.

Monoclonal antibodies are ___

a)

Novel proteins

b)

Gene therapy products

c)

Cell therapy products

d)

Natural proteins

8.

SELECT ALL the techiques use to create biotechnology products

a)

Recombinant DNA

b)

Monoclonal Antibodies

c)

Nucleotide blockade/antisense

d)

Peptide technology

9.

Biotechnology products are typically administered through ___

a)

Oral

b)

Injection

c)

Inhalation

d)

Topical

10.

Monoclonal antibodies are natural antibodies that act as substitute that mimic the immune system's attack on cells.

a)

True

b)

False

11.

The majority of commerical mAb products belong belong to ___ sub-class

a)

IgG

b)

IgE

c)

IgA

d)

IgD

12.

The advantage of smaller fragments of mAb products in therapy are (SELECT ALL)

a)

attaching toxins

b)

act as delivery vehicle

c)

Eliminate diseased cells

d)

Enhance solubility

13.

Which of the following products has the least immunogenicity?

a)

abcximab

b)

canakinumab

c)

trastuzumab

d)

alemtuzumab

14.

-vimab products target ___

a)

virus

b)

fungi

c)

bone

d)

tumor

15.

Which of these is the smallest antibody fragment?

a)

scFv

b)

Fab

c)

F(ab)2

d)

Fc

16.

In which of the these is DNA inserted into patient's cells to replace missing or defective ones?

a)

Gene therapy

b)

DNA hybridization probe technology

c)

Transcriptional therapy

d)

Monoclonal antibody technology

17.

Which of these is an example of a cell therapy product?

a)

talimogene laherparepvec

b)

Nivolumab

c)

Tisagenlecleucel

d)

Nursinesen

18.

Which of these is an example of a gene-therapy product?

a)

Voretigene neparvovec-rzyl intraocular suspension for injection

b)

tisagenlecleucel injection, suspension

c)

Rituximab

d)

Insulin Glargine, Injectable solution

19.

Based on the suffix of the mAb, which of these would you expect to be most immunogenic?

a)

Ofatumab

b)

Detumomab

c)

Rituximab

20.

Which of these types of mAbs is Trastuzumab (Herceptin)?

a)

Chimeric

b)

Humanized

c)

Fully human

d)

Murine

21.

Which of these were the first commercial therapeutic recombinant protein drugs in the US?

a)

Factor VIII and rituximab

b)

Epoetin alfa and tissue plasminogen activator

c)

Insulin and human growth hormone

d)

Filgrastim and interferon alpa-2b