wayground logo

Free Printable Worksheets

Font size

S
M
L
XL
Worksheets

DNA Structure

Total questions: 118

Worksheet time: 1hrs 5mins

Name
Class
Date
1.

What makes up the SIDES of a DNA ladder?

a)

nitrogen bases

b)

sugars & phosphates

c)

genes & chromosomes

d)

RNA

2.

What makes up the rungs (steps) of a DNA ladder?

a)

sugars & phosphates

b)

nitrogen bases

c)

sugars

d)

genes & chromosomes

3.

What SHAPE is DNA?

a)

single strand

b)

straight ladder

c)

double helix (twisted ladder)

d)

DNA has no shape

4.

In DNA. what base always pairs with A?

a)

A

b)

T

c)

C

d)

G

5.

In DNA, what base always pairs with C?

a)

C

b)

T

c)

A

d)

G

6.

If one strand of a DNA molecule has the following order of bases, what will be the correct order of bases on the complementary (matching) strand?

AATTGGCC

a)

AATTGGCC

b)

TTAACCGG

c)

GGCCAATT

d)

GACTGACT

7.

What is DNA made up of?

a)

nucleotides

b)

cytoplasm

c)

RNA

d)

cells

8.

Which is NOT one of the three parts of a nucleotide?

a)

sugar

b)

base

c)

ribosome

d)

phosphate

9.

In what cell part is the DNA located?

a)

ribosome

b)

cytoplasm

c)

mitochondria

d)

nucleus

10.

What is a section of DNA that codes for a specific protein called?

a)

RNA

b)

replication

c)

gene

d)

protein

11.

What is it called when DNA makes a copy of itself?

a)

Translation

b)

Replication

c)

Mitosis

d)

Gene therapy

12.

TRUE or FALSE? During DNA replication, the two new copies of DNA formed are IDENTICAL

a)

True

b)

False

13.

DNA sends a messenger with a copy of the code out of the nucleus to make proteins. What is that messenger?

a)

mRNA

b)

Uracil

c)

DNA

d)

phosphate

14.

During protein synthesis, DNA sends mRNA out of the nucleus to make what?

a)

identical DNA molecules

b)

genes

c)

proteins

d)

fats

15.

How is RNA different than DNA?

a)

It is 2 stranded

b)

It has the sugar deoxyribose

c)

It has the base U instead of T

d)

It is not different- RNA is identical to DNA

16.

What are proteins made of?

a)

Amino acids

b)

chloroplasts

c)

guanine

d)

carbohydrates

17.

What does DNA stand for?

a)

Deoxyribonucleic acid

b)

Diribose nutride acidosis

c)

Dinitro acid

d)

Deoxynitrogenic acid

18.

What scientists were credited with discovering the structure of DNA?

a)

Einstein and Darwin

b)

Watson and Crick

c)

Wallace and Cooper

d)

Wegener and Chargoff

19.

Fill in the matching bases that would appear on the top strand of the DNA molecule pictured, in order.


A G T C A T G A

a)

A G T C A T G A

b)

T T T A A A C C

c)

T C A G T A C T

d)

C A T G A G A T

20.

Challenge- How many TOTAL NUCLEOTIDES are there in the DNA molecule pictured?

a)

5

b)

10

c)

2

d)

20

21.
Which enzyme has the job of unzipping the double helix?
a)
Helicase
b)
Polymerase
c)
Ligase
d)
Primerase
22.
Which enzyme fixes the Okazaki fragments in the lagging strand?
a)
Helicase
b)
Polymerase
c)
Ligase
d)
Primerase
23.
If a strand reads:
3' A A A T T T C 5'
The matching strand would read...
a)
5' T T T A A A G 3'
b)
3' T T T A A A G 5'
c)
5' A A A T T T C 3'
d)
3' U U U A A A G 5'
24.
What are the gaps between the newly synthesized DNA on the lagging strand called?
a)
Okazaki fragments
b)
Polymer gaps
c)
Helicase fragments
d)
Acidic gaps
25.
This picture is illustrating the ____ nature of DNA.
a)
anti-parallel
b)
deoxyribosic
c)
helical
d)
radioactive
26.
3' and 5' refer to...
a)
How effectively the helicase works
b)
What direction the nucleotides are pointing
c)
Where the RNA primer attaches
d)
Okazaki's famous experiment
27.
The enzyme that splits open the DNA creates what's called a fork - where the DNA separates into the lagging strand and the ______ strand.
a)
leading
b)
leveraging
c)
Okazaki
d)
ligase
28.
Polymerase is able to replicate the new DNA ______ along the leading strand.
a)
continuously
b)
only in short fragments
c)
very slowly
d)
prokaryotically
29.
A DNA nucleotide contains all of the following, except...
a)
Deoxyribose
b)
Phosphate group
c)
Nitrogenous base
d)
Cholesterol
30.
What is the shape of DNA?
a)
Double helix
b)
Triple helix
c)
Flat, bilayer
d)
Three-pronged rigid ladder
31.
DNA replication turns one strand of DNA into two new strands of DNA. What percent of each new strand is the old strand?
a)
Half of each new DNA is the old DNA
b)
The old strand of DNA was digested, so none
c)
The new DNA is entirely made up of the old DNA
d)
About every sixth base comes from the old DNA
32.
Sometimes, DNA is called "semi-conservative." Why might this be?
a)
The old strand is "conserved" and used to make the new strands
b)
Uracil is "conserved" in that it is only used to make the new strands
c)
ATP is "conserved" via the usage of facilitated diffusion
d)
Ligase is "conserved" in that it is denatured by the process
33.

The picture below shows the steps of DNA replication beginning with step one and ending with step three.


​Because you are reusing the old, or parent, DNA strand DNA replication is said to be

a)

Semi- Conservative

b)

Semi-discontinuous

c)

Continuous

d)

Fully-Conserveative

34.

The picture below shows an enzyme unwinding and unzipping DNA.

​

​What is the name of this enzyme?

a)

DNA Helicase

b)

DNA Ligase

c)

DNA polyermase

d)

RNA Polymerase

35.

Match he nucleotide with its complementary nucleotide. (DNA to DNA).


Adenine -

a)

Thymine

b)

Guanine

c)

Cytosine

36.

Match he nucleotide with its complementary nucleotide. (DNA to DNA).


Cytosine-

a)

Thymine

b)

Guanine

c)

Adenine

37.

Which enzyme is responsible for adding the free nucleotides to the replicating DNA? ​

a)

DNA Helicase

b)

DNA Ligase

c)

DNA polyermase

d)

RNA Polymerase

38.

Which is the first step?

a)

DNA Helicase unwinds original DNA strand

b)

RNA Primase lays down RNA primer for new nucleotide bases.

c)

DNA polymerase builds new strands by bring in new nucleotide bases.

d)

Ligase knits together fragments on lagging strand

39.

Which is the second step?

a)

DNA Helicase unwinds original DNA strand

b)

RNA Primase lays down RNA primer for new nucleotide bases.

c)

DNA polymerase builds new strands by bring in new nucleotide bases.

d)

Ligase knits together fragments on lagging strand

40.

Which is the third step?

a)

DNA Helicase unwinds original DNA strand

b)

RNA Primase lays down RNA primer for new nucleotide bases.

c)

DNA polymerase builds new strands by bring in new nucleotide bases.

d)

Ligase knits together fragments on lagging strand

41.

Which is the fourth step?

a)

DNA Helicase unwinds original DNA strand

b)

RNA Primase lays down RNA primer for new nucleotide bases.

c)

DNA polymerase builds new strands by bring in new nucleotide bases.

d)

Ligase knits together fragments on lagging strand

42.

Which letter in the picture below depicts the lagging strand in DNA replication?

a)

A

b)

C

c)

B

d)

None of the above

43.

Which letter in the picture below depicts the leading strand in DNA replication?

a)

A

b)

C

c)

B

d)

None of the above

44.

Which letter in the picture below depicts the replication fork in DNA replication?

a)

A

b)

C

c)

B

d)

None of the above

45.

If a person suffered from a disorder where their DNA fragments were unable to fill in the missing slots in between the fragments of the lagging strand, they would most likely have a disorder that affected which enzyme?

a)

DNA Helicase

b)

DNA Ligase

c)

DNA polyermase

d)

RNA Polymerase

46.

DNA replication runs from ______' to _____' and is said to be ______________________

a)

5, 3, antiparallel

b)

3, 5, antiparallel

c)

5, 3, parallel

d)

3, 5, parallel

47.

Okazaki fragments appear on which strand of DNA during DNA replication?

a)

lagging

b)

leading

48.

The directionality of DNA is said to be ___________, because it is side by side by goes in opposite directions.

a)

Anti-directional

b)

Parallel

c)

Anti-parallel

d)

Anti-uniform

49.

​What gray enzyme in the picture is shown removing the RNA primer?

a)

DNA ligase

b)

DNA Polymerase

c)

Exonuclease

d)

RNA Primase

50.
Why does DNA replicate?
a)
To create another copy for the new cell
b)
To create a duplicate copy in case the original gets damaged
c)
To create a new copy to replace the damaged original
51.
The enzyme that unwinds the DNA to prepare for replication
a)
helicase
b)
replicase
c)
polymerase
d)
synthase
52.
order of replication
a)
3, 4, 2, 1
b)
3, 1, 4, 2
c)
2, 1, 4, 3
d)
3, 4, 1, 2
53.
A process in which DNA has the unique ability to make an exact copy of itself.
a)
Replication
b)
Translation
c)
Transcription
54.
Place the following in sequential order
1. Recoil
2. Straightens the double helix
3. Breaks Hydrogen bonds
4. Adds Free nucleotides
a)
1, 2, 3, 4
b)
3, 4, 2, 1
c)
3, 2, 4, 1
d)
2, 3, 4, 1
55.
What will the first four bases of the new DNA strand look like if copying the template strand?
a)
TGGT
b)
ACCA
c)
GTTG
d)
CAAC
56.
Which sequence of DNA bases would pair with this partial strand
CAT TCA CTG
a)
ATG TGA CAG
b)
TAC ACT GTC
c)
GTA AGT GAC
d)
CAT TCA CTG
57.
What are the gaps between the newly synthesized DNA on the lagging strand called?
a)
Okazaki fragments
b)
Polymer gaps
c)
Helicase fragments
d)
Acidic gaps
58.
A DNA nucleotide contains all of the following, except...
a)
Deoxyribose
b)
Phosphate group
c)
Nitrogenous base
d)
Cholesterol
59.
What is the shape of DNA?
a)
Double helix
b)
Triple helix
c)
Flat, bilayer
d)
Three-pronged rigid ladder
60.

DNA replication results in

a)

2 completely new DNA molecules

b)

2 DNA molecules that each contain a strand of the original

c)

1 new DNA molecule and 1 old

d)

1 new molecule of DNA

61.

Enzyme that connects the DNA to the backbone (glues)

a)

Ligase

b)

Polymerase

c)

Helicase

d)

Primase

62.

Enzyme that breaks hydrogen bonds (unzips)

a)

Ligase

b)

Polymerase

c)

Primase

d)

Helicase

63.

Site where replication begins

a)

Polymerase action site

b)

Replication fork

c)

Replication Origin

d)

In the front

64.

The new DNA strand formed after DNA replication is an exact copy of its parent strand

a)

True

b)

False

65.

#4 in the picture

a)

Polymerase

b)

Primase

c)

Helicase

d)

Ligase

66.

#1 in the picture above (builder)

a)

Helicase

b)

Primase

c)

Polymerase

d)

Ligase

67.

#3 setting Primers

a)

Ligase

b)

Helicase

c)

Polymerase

d)

Primase

68.

Number 1 in the picture above

a)

Replication

b)

DNA Polymerase

c)

Primase

d)

Ligase

69.

Match he nucleotide with its complementary nucleotide. (DNA to DNA).


Adenine -

a)

Thymine

b)

Guanine

c)

Cytosine

70.
Which enzyme has the job of unzipping the double helix?
a)
Helicase
b)
Polymerase
c)
Ligase
d)
Primerase
71.
Which enzyme fixes the Okazaki fragments in the lagging strand?
a)
Helicase
b)
Polymerase
c)
Ligase
d)
Primerase
72.
If a strand reads:
3' A A A T T T C 5'
The matching strand would read...
a)
5' T T T A A A G 3'
b)
3' T T T A A A G 5'
c)
5' A A A T T T C 3'
d)
3' U U U A A A G 5'
73.
What are the gaps between the newly synthesized DNA on the lagging strand called?
a)
Okazaki fragments
b)
Polymer gaps
c)
Helicase fragments
d)
Acidic gaps
74.
This picture is illustrating the ____ nature of DNA.
a)
anti-parallel
b)
deoxyribosic
c)
helical
d)
radioactive
75.
3' and 5' refer to...
a)
How effectively the helicase works
b)
What direction the nucleotides are pointing
c)
Where the RNA primer attaches
d)
Okazaki's famous experiment
76.
The enzyme that splits open the DNA creates what's called a fork - where the DNA separates into the lagging strand and the ______ strand.
a)
leading
b)
leveraging
c)
Okazaki
d)
ligase
77.
Polymerase is able to replicate the new DNA ______ along the leading strand.
a)
continuously
b)
only in short fragments
c)
very slowly
d)
prokaryotically
78.
A DNA nucleotide contains all of the following, except...
a)
Deoxyribose
b)
Phosphate group
c)
Nitrogenous base
d)
Cholesterol
79.
What is the shape of DNA?
a)
Double helix
b)
Triple helix
c)
Flat, bilayer
d)
Three-pronged rigid ladder
80.
DNA replication turns one strand of DNA into two new strands of DNA. What percent of each new strand is the old strand?
a)
Half of each new DNA is the old DNA
b)
The old strand of DNA was digested, so none
c)
The new DNA is entirely made up of the old DNA
d)
About every sixth base comes from the old DNA
81.
Sometimes, DNA is called "semi-conservative." Why might this be?
a)
The old strand is "conserved" and used to make the new strands
b)
Uracil is "conserved" in that it is only used to make the new strands
c)
ATP is "conserved" via the usage of facilitated diffusion
d)
Ligase is "conserved" in that it is denatured by the process
82.

The picture below shows the steps of DNA replication beginning with step one and ending with step three.


​Because you are reusing the old, or parent, DNA strand DNA replication is said to be

a)

Semi- Conservative

b)

Semi-discontinuous

c)

Continuous

d)

Fully-Conserveative

83.

The picture below shows an enzyme unwinding and unzipping DNA.

​

​What is the name of this enzyme?

a)

DNA Helicase

b)

DNA Ligase

c)

DNA polyermase

d)

RNA Polymerase

84.

Match he nucleotide with its complementary nucleotide. (DNA to DNA).


Adenine -

a)

Thymine

b)

Guanine

c)

Cytosine

85.

Match he nucleotide with its complementary nucleotide. (DNA to DNA).


Cytosine-

a)

Thymine

b)

Guanine

c)

Adenine

86.

Which enzyme is responsible for adding the free nucleotides to the replicating DNA? ​

a)

DNA Helicase

b)

DNA Ligase

c)

DNA polyermase

d)

RNA Polymerase

87.

Which is the first step?

a)

DNA Helicase unwinds original DNA strand

b)

RNA Primase lays down RNA primer for new nucleotide bases.

c)

DNA polymerase builds new strands by bring in new nucleotide bases.

d)

Ligase knits together fragments on lagging strand

88.

Which is the second step?

a)

DNA Helicase unwinds original DNA strand

b)

RNA Primase lays down RNA primer for new nucleotide bases.

c)

DNA polymerase builds new strands by bring in new nucleotide bases.

d)

Ligase knits together fragments on lagging strand

89.

Which is the third step?

a)

DNA Helicase unwinds original DNA strand

b)

RNA Primase lays down RNA primer for new nucleotide bases.

c)

DNA polymerase builds new strands by bring in new nucleotide bases.

d)

Ligase knits together fragments on lagging strand

90.

Which is the fourth step?

a)

DNA Helicase unwinds original DNA strand

b)

RNA Primase lays down RNA primer for new nucleotide bases.

c)

DNA polymerase builds new strands by bring in new nucleotide bases.

d)

Ligase knits together fragments on lagging strand

91.

Which letter in the picture below depicts the lagging strand in DNA replication?

a)

A

b)

C

c)

B

d)

None of the above

92.

Which letter in the picture below depicts the leading strand in DNA replication?

a)

A

b)

C

c)

B

d)

None of the above

93.

Which letter in the picture below depicts the replication fork in DNA replication?

a)

A

b)

C

c)

B

d)

None of the above

94.

If a person suffered from a disorder where their DNA fragments were unable to fill in the missing slots in between the fragments of the lagging strand, they would most likely have a disorder that affected which enzyme?

a)

DNA Helicase

b)

DNA Ligase

c)

DNA polyermase

d)

RNA Polymerase

95.

DNA replication runs from ______' to _____' and is said to be ______________________

a)

5, 3, antiparallel

b)

3, 5, antiparallel

c)

5, 3, parallel

d)

3, 5, parallel

96.

Okazaki fragments appear on which strand of DNA during DNA replication?

a)

lagging

b)

leading

97.

The directionality of DNA is said to be ___________, because it is side by side by goes in opposite directions.

a)

Anti-directional

b)

Parallel

c)

Anti-parallel

d)

Anti-uniform

98.

​What gray enzyme in the picture is shown removing the RNA primer?

a)

DNA ligase

b)

DNA Polymerase

c)

Exonuclease

d)

RNA Primase

99.
Why does DNA replicate?
a)
To create another copy for the new cell
b)
To create a duplicate copy in case the original gets damaged
c)
To create a new copy to replace the damaged original
100.
The enzyme that unwinds the DNA to prepare for replication
a)
helicase
b)
replicase
c)
polymerase
d)
synthase
101.
order of replication
a)
3, 4, 2, 1
b)
3, 1, 4, 2
c)
2, 1, 4, 3
d)
3, 4, 1, 2
102.
A process in which DNA has the unique ability to make an exact copy of itself.
a)
Replication
b)
Translation
c)
Transcription
103.
Place the following in sequential order
1. Recoil
2. Straightens the double helix
3. Breaks Hydrogen bonds
4. Adds Free nucleotides
a)
1, 2, 3, 4
b)
3, 4, 2, 1
c)
3, 2, 4, 1
d)
2, 3, 4, 1
104.
What will the first four bases of the new DNA strand look like if copying the template strand?
a)
TGGT
b)
ACCA
c)
GTTG
d)
CAAC
105.
Which sequence of DNA bases would pair with this partial strand
CAT TCA CTG
a)
ATG TGA CAG
b)
TAC ACT GTC
c)
GTA AGT GAC
d)
CAT TCA CTG
106.
What are the gaps between the newly synthesized DNA on the lagging strand called?
a)
Okazaki fragments
b)
Polymer gaps
c)
Helicase fragments
d)
Acidic gaps
107.
A DNA nucleotide contains all of the following, except...
a)
Deoxyribose
b)
Phosphate group
c)
Nitrogenous base
d)
Cholesterol
108.
What is the shape of DNA?
a)
Double helix
b)
Triple helix
c)
Flat, bilayer
d)
Three-pronged rigid ladder
109.

DNA replication results in

a)

2 completely new DNA molecules

b)

2 DNA molecules that each contain a strand of the original

c)

1 new DNA molecule and 1 old

d)

1 new molecule of DNA

110.

Enzyme that connects the DNA to the backbone (glues)

a)

Ligase

b)

Polymerase

c)

Helicase

d)

Primase

111.

Enzyme that breaks hydrogen bonds (unzips)

a)

Ligase

b)

Polymerase

c)

Primase

d)

Helicase

112.

Site where replication begins

a)

Polymerase action site

b)

Replication fork

c)

Replication Origin

d)

In the front

113.

The new DNA strand formed after DNA replication is an exact copy of its parent strand

a)

True

b)

False

114.

#4 in the picture

a)

Polymerase

b)

Primase

c)

Helicase

d)

Ligase

115.

#1 in the picture above (builder)

a)

Helicase

b)

Primase

c)

Polymerase

d)

Ligase

116.

#3 setting Primers

a)

Ligase

b)

Helicase

c)

Polymerase

d)

Primase

117.

Number 1 in the picture above

a)

Replication

b)

DNA Polymerase

c)

Primase

d)

Ligase

118.

Match he nucleotide with its complementary nucleotide. (DNA to DNA).


Adenine -

a)

Thymine

b)

Guanine

c)

Cytosine

Similar Resources on Wayground

Biology Review Test

113 questions

Biology Review Test

quiz

Worksheet

•

9th - 12th Grade

Cells - Human Reproduction Part #1

118 questions

Cells - Human Reproduction Part #1

quiz

Worksheet

•

9th Grade

Quarter 2 Review

113 questions

Quarter 2 Review

quiz

Worksheet

•

9th Grade

Human Body Review- Pre-AP Bio

123 questions

Human Body Review- Pre-AP Bio

quiz

Worksheet

•

9th Grade

CAT 4 BIOLOGY EOC

121 questions

CAT 4 BIOLOGY EOC

quiz

Worksheet

•

9th - 10th Grade

Semester 2 Review for Final

122 questions

Semester 2 Review for Final

quiz

Worksheet

•

9th Grade

Unit 5 - Gene Expression Study Guide

120 questions

Unit 5 - Gene Expression Study Guide

quiz

Worksheet

•

9th Grade

Fresh Bio Semester Review

117 questions

Fresh Bio Semester Review

quiz

Worksheet

•

9th Grade