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POP QUIZ CHAPTER 4- BIOCATALYSIS

Total questions: 40

Worksheet time: 34mins

Name
Class
Date
1.

Enzyme affect the speed of chemical reaction without being consumed, they are referred to as

a)

hydrogen acceptor

b)

activation energy

c)

biocatalyst

d)

cytochrome

2.

Enzymes are important biological catalysts because they:

a)

supply the energy to initiate a biochemical reaction

b)

increase the free energy of a biochemical reaction

c)

lower the entropy and enthalpy of a biochemical reaction

d)

lower the activation energy of a biochemical reaction

3.

Most enzyme are ___________

a)

carbohydrate

b)

lipid

c)

protein

d)

DNA

4.

The line on the graph labeled A represents the:

a)

activation energy with an enzyme

b)

activation energy without an enzyme

c)

free energy of the reactants

d)

change in entropy and enthalpy

5.

Parts of the enzyme molecule that interact with a substrate are called:

a)

cofactors

b)

active sites

c)

induced-fit models

d)

reaction sites

6.

Which of the following is true of enzymes?

a)

Enzymes may require a non-protein cofactor or ion for catalysis to take place

b)

Enzyme function is influenced by physical and chemical environmental factors such as pH and temperature

c)

Enzymes increase the rate of chemical reaction by lowering activation energy

d)

All of these are correct

7.

Only a small amount of enzyme is needed for a large amount of substrate because _______

a)

Enzymes do not change at the end of a reaction and as such can be reused

b)

A small amount of enzyme can provide enough energy to continue the reaction

c)

More enzymes are formed while reaction takes place

d)

Enzymes act till completion of a reaction or not at all

8.

Which of the following match with the characteristics of enzyme that the bonds are broken down and cause enzyme is not function anymore

a)

will denature in high pH and temperature

b)

enzyme is highly specific

c)

will denature in extreme pH & very high temperature

d)

enzyme is reusable

9.

Enzyme that catalyses the transfer of functional group of atoms from one molecule to another. This enzyme is

a)

Isomerases

b)

Transferases

c)

Oxidoreductase

d)

Lyases

10.

Enzymes in group Isomerases catalyse

a)

the rearrangement of atoms

b)

the transfer of functional group of atoms

c)

the breaking of chemical bond

d)

the formation of bonds

11.

What is structure C?

a)

Substrate-enzyme complex

b)

Substrate-enzyme complement

c)

Enzyme-substrate complement

d)

Enzyme-substrate complex

12.

Which of the following statements regarding enzyme is TRUE

a)

Enzyme decreases the free energy change of a reaction

b)

Enzyme changes the direction of chemical reaction

c)

Enzyme increase rate of reaction

d)

Enzyme prevents changes in substrate concentration

13.

Watch the animation and identify the hypothesis involved

a)

Lock and Key hypothesis

b)

Induced Fit hypothesis

c)

Enzyme-Substrate hypothesis

14.

Which of the following does not affect enzyme activity?

a)

temperature

b)

pH

c)

substrate concentration

d)

sugar

15.

What will happen when enzyme is denatured?

a)

A proton is added or removed from the enzyme.

b)

It reaches its temperature at which it exhibits maximum activity.

c)

A substance binds to it which slows or stops its normal catalytic function.

d)

It changes shape and the active site no longer matches the shape of the substrate molecule.

16.

This graph shows the enzyme activity when substrate concentration is increased. What is the reason of this enzyme activity pattern?

a)

There is no available substrate.

b)

The active site changes its shape, thus, preventing the substrate from binding.

c)

High substrate concentration affects the temperature at which enzymes work best.

d)

Enzymes are all occupied, the incoming substrate molecules must wait for an active empty site.

17.

Why an increased in temperature (up to the optimum temperature) increases the enzyme reaction?

a)

Because kinetic energy of molecules decreases.

b)

Because kinetic energy of molecules increases.

c)

Because denaturation of enzymes occurs.

d)

Because inhibitors are eliminated at this condition.

18.

Competitive inhibition can be overcome by _______________

a)

increase the concentration of substrate

b)

reduce the concentration of enzyme

c)

increase the concentration of enzyme

d)

reduce the concentration of substrate

19.

If one continues to increase the temperature in an enzyme-catalyzed reaction, the rate of the reaction:

a)

increases and then levels off

b)

decreases and then levels off

c)

increases and then decreases rapidly

d)

decreases and then increases rapidly

20.

Select the name of the mechanism of the binding of a substrate to the active site of enzyme which is the active site is flexible.

a)

active site

b)

cofactor

c)

activation energy

d)

Induced fit

21.

Consider the following: “Succinate dehydrogenase catalyzes the conversion of succinate to fumarate. The reaction is inhibited by malonic acid, which resembles succinate but cannot be acted upon by succinate dehydrogenase. Increasing the ratio of succinate to malonic acid reduces the inhibitory effect of malonic acid”.

Which of the following is correct?

a)

Succinate dehydrogenase is the enzyme, and fumarate is the substrate

b)

Succinate dehydrogenase is the enzyme, and malonic acid is the substrate

c)

Succinate is the substrate, and fumarate is the product

d)

Fumarate is the substrate, and malonic acid is a non-competitive inhibitor

22.

What is an organic non-protein "helper" of an enzyme molecule called?

a)

accessory enzyme

b)

allosteric group

c)

cofactor

d)

functional group

23.

Which of the following is true of enzymes?

a)

Enzymes may require a non-protein cofactor or ion for catalysis to take place

b)

Enzyme function is influenced by physical and chemical environmental factors such as pH and temperature

c)

Enzymes increase the rate of chemical reaction by lowering activation energy

d)

All of these are correct

24.

In which way the enzymatic reaction can be increased if the enzymes are saturated with the substrate?

a)

add more enzymes

b)

add more substrate

c)

increase the temperature

d)

add cofactor

25.

How does enzyme lower the activation energy?

a)

Bring substrate closer to each other

b)

Increase the kinetic energy of substrate

c)

Weakening the bonds inside the substrate

d)

Bring substrate together into correct orientation

26.

what reduces the productivity of enzymes by blocking substrates from entering active sites?

a)

non competitive inhibitors

b)

competitive inhibitors

c)

coenzymes

d)

cofactors

27.

Which of the following are the properties of enzyme?

I        Enzymes are highly specific.
II       All enzymes are denatured at 60°c60\degree c  
III      A large number of enzymes is needed to react with large number of substrate.
IV       Enzymes lower the activation energy.

a)

I only.

b)

I and IV only.

c)

I, II and III 

d)

I, II and IV

28.

The protein part of an enzyme that binds to prosthetic group to form a functional enzyme is called

a)

holoenzyme

b)

apoenzyme

c)

coenzyme

d)

conjugated protein

29.

Which of these statements are true about competitive inhibitor?

a)

Inhibitor and substrate has similar structure

b)

The inhibitor binds to the allosteric site

c)

The conformation of active site changed due to the inhibitor

d)

Quantity of product formed is the same as reaction with no inhibitor

30.
Succinate dehydrogenase catalyzes the conversion of succinate to fumarate. The reaction is inhibited by malonic acid, which resembles succinate but cannot be acted upon by succinate dehydrogenase. Increasing the ratio of succinate to malonic acid reduces the inhibitory effect of malonic acid. What is malonic acid's role with respect to succinate dehydrogenase?
a)
It is a competitive inhibitor.
b)
It is an allosteric regulator.
c)
It is able to bind to succinate.
d)
It blocks the binding of fumarate.
31.
The place, other than the active site, where activators and inhibitors bind to an enzyme is called the ________ site.
a)
competitive
b)
allosteric
c)
alterior
d)
rate
32.

When a molecule can occupy the same active site as the substrate, a situation called __________________ can result

a)

Competitive lnhibition

b)

Allosteric Regulation

c)

Non-Competitive Inhibition

d)

Feedback Inhibition

33.

A receptor site that a molecule can bind to that changes the shape of the active site is called a(n):

a)

Allosteric Site

b)

Active Site

c)

DiSulphide Bridge

d)

MHC Receptor

34.

Molecules that bind to enzymes and enhance an enzyme's ability are called:

a)

CoFactors

b)

CoEnzymes

c)

Allosteric Inhibitors

d)

Allosteric Activators

35.

Organic molecules that temporarily bind to enzymes and enhance an enzyme's ability are called:

a)

CoFactors

b)

CoEnzymes

c)

Allosteric Inhibitors

d)

Allosteric Activators

36.

When an enzyme tightens around a substrate, this is called:

a)

An awkward hug

b)

Induced fit

c)

Competitive Inhibition

d)

Non competitive Inhibition

37.

What's going on in this picture?

a)

The enzyme is taking the red substrate and turning it blue

b)

The enzyme's active site is blocked by a competitive inhibitor

c)

The enzyme can't function if too many substrates are trying to bind

d)

This is an example of an anabolic enzyme reaction

38.

Which is true of non-competitive inhibition?

a)

It is irreversible

b)

The inhibitor binds only to the active site of enzyme

c)

The inhibitor binds to enzyme to lower activation energy

d)

It can be reduced by increasing the concentration of the substrate

39.

Which type of reversible enzyme inhibitor binds to both the free enzyme and the enzyme-substrate complex?

a)

Non-competitive inhibitor

b)

End product inhibitor

c)

Competitive inhibitor

d)

None of the above

40.

Describe the effect of temperature as it increase

a)

kinetic energy of substrate and enzyme increased

b)

rate of reaction is maximum

c)

collision between substrate and enzyme's active site increased