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WorksheetsPeds Exam III - Oncology & Neurology
Total questions: 58
Worksheet time: 33mins
The most common childhood malignancy is?
ALL
AML
CLL
CML
The 3 P's associated with ALL are?
Pallor
Petechiae
Purpura
Pancreatitis
The most useful initial test for evaluation of ALL is?
CBC
CMP
PET scan
EKG
This malignancy is associated with congenital conditions, chromosomal and molecular abnormalities
ALL
AML
CLL
CML
The presence of the Philadelphia chromosome is consistent with what form of malignancy?
ALL
AML
CLL
CML
Which of the following bloodlines are commonly effected in patients with leukemia?
Erythrocytes
Leukocytes
Thrombocytes
____ symptoms which include fever, weight loss, and drenching night sweats are associated with Hodgkin and NHL
A
B
C
D
History of Epstein Barr virus infection, mononucleosis, and HIV are RF associated with the development of Hodgkin and NHL
True
False
The presence of Reed-Sternberg cells is diagnostic for?
Hodgkin's Lymphoma
Non-Hodgkin's Lymphoma
Multiple Myeloma
Chronic Myeloid Leukemia
A 6 year old presents with his mother for swelling to the jaw that began 3 weeks ago. The mother reports moving from Africa to the US 2 months ago. On exam, there are large hard submandibular lymph nodes that are non-mobile. Labs show positive EBV antibodies and biopsy shows a "starry sky" pattern. Based off these results what is the most likely type of NHL?
Burkitt lymphoma
Diffuse large B cell lymphoma
Lymphoblastic lymphoma
Anaplastic large cell lymphoma
Sites of malignancy associated with NHL are?
lymph nodes
thymus
liver
spleen
femurs
Which of the following is the most common brain tumor in children?
Astrocytoma
Medulloblastoma
Ependymomas
Neuroblastoma
The most frequent type of astrocytoma are grade _____ and occur in the ____
I
IV
cerebellum
cerebrum
III
A rapidly growing, invasive and malignant tumor that occurs bimodally in childhood and is associated with certain syndromes is known as?
Astrocytoma
Medulloblastoma
Ependymomas
Neuroblastoma
Ependymomas are the least frequent CNS tumor of children, but form at what site most often?
Cerebellum
Ventricles
Brainstem
Pons
A 14 month old presents with his mother to the ER after the mother noted a mass to the abdomen with some abdominal pain. On exam there is a palpable mass and periorbital ecchymosis is noted. CT shows a mass located on the adrenal glands and UA is positive for noradrenaline. What is the most likely diagnosis?
Neuroblastoma
Wilm's Tumor
Ewing's Sarcoma
Astrocytoma
A palpable painless abdominal mass that is often found by a caretaker or during a physical exam that develops on the kidney during embryonic development is known as?
Wilm's tumor
Hodgkin's lymphoma
Grawitz tumor
Klatskin's tumor
A 16 y/o M presents with his father to the ER after the developing bone pain of the leg that has become progressively worse. Exam is unremarkable except for pain with ROM of the leg. Labs show LDH of 1000 IU/L (300-700 IU/L). The patient is referred to oncology for biopsy to check for which of the following?
Neuroblastoma
Wilm's Tumor
Ewing's Sarcoma
Medulloblastoma
The biopsy finding associated with Ewing's sarcoma is?
Reed-Sternberg cells
Starry night appearance
Small, blue, round cells
Homogenous infiltration of blasts
Osteosarcoma is a non-aggressive form of cancer characterized by chromosomal instability
True
False
Rhabdomyosarcoma is a malignancy which arises from _____ embryonic stem cells and has potential to differentiate into skeletal muscle cells which can vary the site of tumor formation.
ectoderm
mesenchymal
endoderm
neural crest
The most common site of rhabdomyosarcoma (35%) is _____ and occurs in school-aged children.
Head & neck
GU
Extremities
Trunk & misc. sites
Leukocoria is the most common presenting sign of which of the following?
pediatric cataracts
retinoblastoma
strabismus
pediatric glaucoma
It is imperative for treatment of retinoblastoma. If let untreated there is a 100% mortality rate.
True
False
A grandmother presents with her 24 month granddaughter to the clinic. Grandmother reports that the child has been eating dirt, chalk, and ice. You inform the grandmother that is known as pica and a symptom commonly associated with?
iron deficiency anemia
pernicious anemia
sickle cell anemia
aplastic anemia
A Hb of ____ at the 1 year screening visit can be closely monitored or empirically treated with PO iron supplements
10-11 mg/dL
12-13 mg/dL
5-6 mg/dL
4-5 mg/dL
A mother presents with her 15 month old child who is HbSS. The mother reports some increased swelling of the child's hands which are painful to touch. This sign is known as ____ and is the most common presenting sx of sickle cell disease
dactylitis
polydactyly
Reynaud's phenomenon
juvenile idiopathic arthritis
It is important that children with sickle cell disease receive annual influenza vaccine and the pneumococcal vaccine.
True
False
α-thalassemia patients may be asymptomatic or have mild microcytic anemia unless there is a deletion of how many α-Hb genes? (Select all that apply)
0
1
2
3
4
Children with β-thalassemia minor should be treated with chronic transfusion with iron chelation or stem cell transplant
True
False
Disorders of hemostasis that result in prolonged bleeding times include which of the following?
Hemophilia
Von Willebrand disease
Factor V Leiden
Antiphospholipid antibody syndrome
Antithrombin III deficency
Treatment of children with thrombolytic disease including anticoagulation with heparins or warfarin.
True
False
The criteria for diagnosis of febrile seizures includes which of the following?
age 3 month - 6 years
fever of greater than 38.8° C (101.8° F)
non-CNS infection
up to date on all vaccinations
illness that has been taking place for at least 5 days
Common causes of febrile seizures include which of the following?
URI
Otitis media
Gastroenteritis
UTI
Following live attenuated virus vaccination
The phase of seizure associated with rapid contracting jerking movements is known as the ____ phase
prodrome
tonic
clonic
post-ictal
Treatment of febrile seizures lasting < 15 minutes include which 2 of the following?
Antipyretics - Acetaminophen
Benzodiazepines - Lorazepam
Anticonvulsants - Phenytoin
Airway protection with intubation
Supportive care
The classic triad of signs & symptoms associated with meningitis is?
Headache
Fever
Nuchal rigidity
Photophobia
Vomiting
The most common infectious organism of bacterial meningitis is newborns is?
Group B Streptococcus
S. pneumoniae
N. meningitidis
E. coli
The most common infectious organism of bacterial meningitis is infants and children is?
Group B Streptococcus
S. pneumoniae
N. meningitidis
E. coli
The most common infectious organism of bacterial meningitis in unvaccinated adolescents and young adults is?
Group B Streptococcus
S. pneumoniae
N. meningitidis
E. coli
It is not abnormal to see 1-3 PMNs in CSF of a child in the first 3 months.
True
False
Passive flexion of the neck which causes tension and pain of inflamed meninges, resulting in flexion of the hips to relive pain is known as?
Kernig sign
Brudzinksi sign
Ausptiz sign
Stop sign
Which of the following CSF findings are consistent with bacterial meningitis?
Normal opening pressure
Purulent CSF appearance
High WBC
Elevated glucose
Elevated protein
Empirical abx treatment of children >3 months includes a ceftriaxone/cefotaxime + vancomycin
True
False
Viral meningitis is most commonly caused by which of the following?
Adenovirus
Norovirus
Enterovirus
Coxsackievirus
It is important to isolate patients with viral meningitis as the risk of spread and the development of meningitis is very high.
True
False
The most useful diagnostic method for evaluation of viral meningitis as results return in 24-48 hours is?
PCR
CBC
CMP
CT
Viral culture
A 7 month old is admitted to your service for suspected viral meningitis. On exam the patient appears moderately ill. It would be acceptable to start empiric antibiotics until negative cultures are resulted.
True
False
Which of the following CSF findings are associated with viral meningitis?
Elevated WBCs predominantly monocytes
Decreased glucose
Normal protein
Turbid appearance
Slightly elevated opening pressure
Sensory processing disorder may result in which of the following?
resistance to change
problems with motor skills
lack of social skills
poor self control
trouble focusing
Sensory processing disorder is often seen in concomitant with ASD and ADHD
True
False
A father presents with his 4 year old son for evaluation. The father notes increased sensitivity to light and sound and the child refuses to wear shoes reporting they are "too tight." The father also states the child is avoidant of touch including hugs and refuses to cuddle. You would likely diagnosis this child with what form of SPD?
Hypoactive
Hyperactive
AD(H)D is a syndrome which includes which of the following?
Inattention
Hyperactivity
Impulsivity
Frequent tantrums
According to the DSM-V diagnosis of AD(H)D requires impairment in at least _ settings which includes home, school, occupation, with friends or relatives, in other activities
1
2
3
4
0
According to the DSM-V diagnosis of AD(H)D requires at least _ of 9 symptoms to be present for diagnosis
9
5
6
4
7
Consistent structure of daily routines and positive behavior reinforcement are both part of behavior modification and educational interventions for AD(H)D
True
False
Poor outcomes of adolescence and adulthood for this with AD(H)D includes the following
Coexisting low intelligence
Aggressiveness
Social and interpersonal problems
Parental psychopathology
Early recognition and intervention
Stimulant medications used to treat AD(H)D include
Ritalin
Concerta
Vyvanse
Adderall
Strattera
