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final rad bio

Total questions: 73

Worksheet time: 37mins

Name
Class
Date
1.

A codon is a _______________.

a)

genetic message

b)

cell organelle

c)

protein molecule

d)

somatic cell

2.

A type of DNA damage that may not be reversible is a

_________________.

a)

base change or loss

b)

severed side rail

c)

rung breakage

d)

cross linking

3.

All the hereditary information about an individual is contained in the _______ cells.

a)

blood

b)

germ

c)

brain

d)

skin

4.

An indirect effect from ionizing radiation occurs on a ___________ molecule.

a)

water

b)

DNA

c)

free radical

d)

target

5.

DNA is contained in the __________________ of the cell nucleus

a)

cytoplasm

b)

chromosomes

c)

proteins

d)

RNA

6.

DNA is located in the ____________ of the cell.

a)

wall

b)

cytoplasm

c)

nucleus

d)

nucleus and cytoplasm

7.

DNA is the most radiosensitive molecule in the human body.

a)

true

b)

false

8.

Free radicals can be damaging because they are

______________________.

a)

radioactive

b)

highly reactive

c)

unstable and highly reactive

d)

unstable

9.

Humans are most radiosensitive during ________________.

a)

infancy

b)

adulthood

c)

old age

d)

fetal stages

10.

If a macromolecule has (a) _____________, it will break

down into smaller molecules.

a)

cross-linking

b)

point lesion

c)

main-chain scission

d)

point mutation

11.

If a macromolecule has (a) _____________, it will break

down into smaller molecules.

a)

nonthreshold

b)

threshold

c)

nonlinear

d)

nonlinear

12.

In vitro is irradiation within the cell or body.

a)

true

b)

false

13.

Ionizing events from irradiation are considered to be direct effects if they occur with ___________ molecules

a)

water and DNA

b)

DNA

c)

protein

d)

water

14.

Meiosis is the process of cell division for ___________

cells.

a)

genetic

b)

muscles

c)

skin

d)

somatic

15.

Metabolism consists of catabolism and anabolism

a)

True

b)

false

16.

Radiation induced genetic damage follows a ___________________ dose-response relationship.

a)

nonlinear-threshold

b)

nonlinear-nonthreshold

c)

linear-nonthreshold

d)

linear-threshold

17.

Ribonucleic acid (RNA) is located primarily in the

_________________.

a)

cytoplasm

b)

cell wal

c)

nucleus

d)

ribosomes

18.

The RBE of diagnostic x-rays is equal to _____.

a)

1

b)

20

c)

5

d)

10

19.

The __________ is the basic functional unit of all plants

and animals

a)

DNA

b)

macromolecule

c)

cell

d)

lipid

20.

The ______________ have the function of cleaning

contaminants from the cell.

a)

mitochondria

b)

lysosomes

c)

chromatids

d)

ribosomes

21.

The _______________ in the cell are nucleic acids.

a)

DNA

b)

lipids

c)

RNA

d)

dna and rna

22.

The cell “engines” are the _________________.

a)

lysosomes

b)

mitochondria

c)

nucleoloi

d)

ribosomes

23.

The human body is composed of about 80% ____

a)

protien

b)

carbohydrates

c)

water

d)

nucleic acids

24.

The law of ______ states that radiosensitivity of living tissue is a function of the metabolism and maturation of that tissue.

a)

Bergonie and Tribondeau

b)

Hurter and Driffield

c)

Watson and Crick

d)

Roentgen and Plank

25.

The metabolic process of building large molecules from smaller ones is called ______________.

a)

catabolism

b)

homeostasis

c)

anabolism

d)

synthesis

26.

The most radiosensitive macromolecule is ___________.

a)

mRNA

b)

tRNA

c)

protein

d)

DNA

27.

The most radiosensitive target molecule in the human cell is the _________.

a)

hormone

b)

DNA

c)

glucose

d)

protein

28.

The only principal molecules in the body which are simple molecules are __________ molecules

a)

water

b)

carbohydrate

c)

lipid

d)

protein

29.

The principal radiation interaction within the human body is with _____________.

a)

RNA

b)

water

c)

DNA

d)

macromolecules

30.

The principal radiation interactions within the human body are assumed to be ________________.

a)

DNA damage

b)

direct effects

c)

indirect effects

d)

cell destruction

31.

The two major parts of the cell are the nucleus and the ________________.

a)

nucleolus

b)

mitochondria

c)

cell wall

d)

cytoplasm

32.

Tissues that are ____________ with a _______ metabolic rate are more radiosensitive.

a)

immature; low

b)

immature; high

c)

mature; low

d)

mature; high

33.

Ameasure of the rate at which energy is transferred from ionizing radiation to soft tissue is know as 

a)

linear energy transfer

b)

threshold dose

c)

energy absorb dose

d)

entrance skin exposure

34.

In a linear threshold dose, any dose regardless of its size is expected to produce a response.

a)

True

b)

False

35.

Humans are more radioresistant at birth.

a)

true

b)

false

36.

In vitro refers to outside the body or outside the cell. 

a)

true

b)

false

37.

Radiation dose-response relationship is a mathematical relationship between various radiation dose levels and the magnitude of the observe response.

a)

true

b)

false

38.

Which of these corollarries from law of Bergonie and Tribondeau are true

a)

stem cells are radiosensitive

b)

younger tissues and organs are radiosensitive

c)

tissues with high metabolic activity are radiosensitive

d)

Slow proliferation rate cells are more radiosensitive

39.

What three major effects occur when macromolecules are irradiated in solution in vitro?

a)

molecule synthesis

b)

point lesion

c)

cross-linking

d)

main-chain scission

40.

Catabolism is the process of breaking down large molecules into smaller molecules with a release of energy.

a)

true

b)

false

41.

Synthesis of macromolecules from smaller molecules is referred as Metabolism.

a)

true

b)

false

42.

The principal effect of radiation on humas is indirect effect.

a)

true

b)

false

43.

When the ionizing event occurs on the target molecule, the effect of radiation is direct.

a)

true

b)

false

44.

Principle that all plants and animals contain cells as their basic functional units

a)

human radiation response

b)

Human Body composition

c)

cell theory

d)

molecular composition

45.

Organic molecules contain carbon.

a)

hydrogen

b)

carbon

c)

oxygen

d)

nitrogen

46.

What is the most abundant molecule in the human body?

a)

urea

b)

DNA

c)

water

d)

mRNA

47.

Proteins are made up of amino acids that provides structure and support to the human body.

a)

True

b)

false

48.

Carbohydrates provide fuel for cell metabolism. 

a)

true

b)

false

49.

Deterministic is a theory that suggesting that all events, including moral choices, are completely determined by previously existing causes.

a)

true

b)

false

50.

Acute radiation effects can also be referred as short term effect.

a)

true

b)

false

51.

Acute Radiation Syndromes include: 

a)

hermatologic syndrome

b)

gastrontestinal (GI) syndrome

c)

central nervous system (CNS) syndrome

d)

all of the above

52.

Select the acute radiation lethality stages in order

a)

Prodromal period, latent period, manifestation period

b)

Manifestation period, latent period, prodromal period

c)

latent period, prodromal period, manifestation period

d)

prodromal period, manifestation period, latent period

53.

Alethal whole-body radiation dose that causes 75% of irradiated subjects to die within 30 days can be define as:

a)

Lethal Dose 75/30

b)

Lethal Dose 30/75

c)

Whole Body Exposure 75/30

d)

Lethality 75/30

54.

Shrinkage of an organ or tissue caused by cell death is defined as:

a)

atrophy

b)

desquamation

c)

tissue decay

d)

tissue damage

55.

Damage to basal cells results in the long term manifestation of erythema.

a)

true

b)

false

56.

A chromosome hit represents severe damage to the DNA.

a)

true

b)

false

57.

Select the response curve describing the skin effects following a nonlinear, threshold dose.

a)

A

b)

B

c)

C

d)

D

58.

Stochastic effects of radiation exposure are the result of low doses delivered over a long period.

a)

TRUE

b)

FALSE

59.

At worst, humans can expect a reduced life of approximately 5 days for every 10 mGyt

a)

true

b)

false

60.

Low-dose, chronic irradiation does impairs fertility.

a)

true

b)

false

61.

The most radiosensitive period during pregnancy is

a)

first trimester

b)

second trimester

c)

third trimester

d)

fourth trimester

62.

Radiation exposure in utero does retard the growth and development of the newborn.

a)

true

b)

false

63.

Select the response curve descriving the genetic effects following linear, nonthreshold response.

a)

A

b)

B

c)

C

d)

D

64.

A __________ effect increases in incidence but not severity as the dose increases.

a)

stochastic

b)

deterministic

c)

localized

d)

nonstochastic

65.

Chronic low doses of radiation have ________ effect on fertility.

a)

an increasing

b)

a strong

c)

a weak

d)

no

66.

Data showing radiation-induced human genetic abnormalities __________________.

a)

indicates responses to high doses

b)

. is being studied by the BEIR

c)

does not exist

d)

indicates responses to low doses

67.

It is difficult to link cancer to radiation exposure because it occurs ___________ in the population.

a)

in high proportion

b)

very rarely

c)

with severity

d)

onlu in the elderly

68.

Radiation protection guidelines are based on _______________________.

a)

stochastic effects of radiation

b)

stochastic and deterministic effects of radiation

c)

deterministic effects of radiation

d)

d. lethal effects of radiation

69.

____________ is a stochastic effect of radiation exposure.

a)

nausea

b)

epilation

c)

erythema

d)

cancer

70.

During the latent period, the radiation victim experiences _____________.

a)

nausea and vomiting

b)

hair loss

c)

skin erythema

d)

well-being

71.

High doses of radiation to a localized area can lead to ____________ of tissues and organs in that area.

a)

reduction in size

b)

total loss of function

c)

reduction in size, shrinkage, and total loss of function

d)

shrinkage

72.

The LD 50/60 is the dose of radiation to the whole-body that will result in death within __________ to _____% of the irradiated population.

a)

60 days; 50

b)

50 minutes; 60

c)

60 minutes; 50

d)

50 days; 60

73.

There is usually a _______________ before the symptoms of acute radiation syndromes appear

a)

loss of hair

b)

latent period

c)

recovery period

d)

prolonged illness