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Worksheetsfinal rad bio
Total questions: 73
Worksheet time: 37mins
A codon is a _______________.
genetic message
cell organelle
protein molecule
somatic cell
A type of DNA damage that may not be reversible is a
_________________.
base change or loss
severed side rail
rung breakage
cross linking
All the hereditary information about an individual is contained in the _______ cells.
blood
germ
brain
skin
An indirect effect from ionizing radiation occurs on a ___________ molecule.
water
DNA
free radical
target
DNA is contained in the __________________ of the cell nucleus
cytoplasm
chromosomes
proteins
RNA
DNA is located in the ____________ of the cell.
wall
cytoplasm
nucleus
nucleus and cytoplasm
DNA is the most radiosensitive molecule in the human body.
true
false
Free radicals can be damaging because they are
______________________.
radioactive
highly reactive
unstable and highly reactive
unstable
Humans are most radiosensitive during ________________.
infancy
adulthood
old age
fetal stages
If a macromolecule has (a) _____________, it will break
down into smaller molecules.
cross-linking
point lesion
main-chain scission
point mutation
If a macromolecule has (a) _____________, it will break
down into smaller molecules.
nonthreshold
threshold
nonlinear
nonlinear
In vitro is irradiation within the cell or body.
true
false
Ionizing events from irradiation are considered to be direct effects if they occur with ___________ molecules
water and DNA
DNA
protein
water
Meiosis is the process of cell division for ___________
cells.
genetic
muscles
skin
somatic
Metabolism consists of catabolism and anabolism
True
false
Radiation induced genetic damage follows a ___________________ dose-response relationship.
nonlinear-threshold
nonlinear-nonthreshold
linear-nonthreshold
linear-threshold
Ribonucleic acid (RNA) is located primarily in the
_________________.
cytoplasm
cell wal
nucleus
ribosomes
The RBE of diagnostic x-rays is equal to _____.
1
20
5
10
The __________ is the basic functional unit of all plants
and animals
DNA
macromolecule
cell
lipid
The ______________ have the function of cleaning
contaminants from the cell.
mitochondria
lysosomes
chromatids
ribosomes
The _______________ in the cell are nucleic acids.
DNA
lipids
RNA
dna and rna
The cell “engines” are the _________________.
lysosomes
mitochondria
nucleoloi
ribosomes
The human body is composed of about 80% ____
protien
carbohydrates
water
nucleic acids
The law of ______ states that radiosensitivity of living tissue is a function of the metabolism and maturation of that tissue.
Bergonie and Tribondeau
Hurter and Driffield
Watson and Crick
Roentgen and Plank
The metabolic process of building large molecules from smaller ones is called ______________.
catabolism
homeostasis
anabolism
synthesis
The most radiosensitive macromolecule is ___________.
mRNA
tRNA
protein
DNA
The most radiosensitive target molecule in the human cell is the _________.
hormone
DNA
glucose
protein
The only principal molecules in the body which are simple molecules are __________ molecules
water
carbohydrate
lipid
protein
The principal radiation interaction within the human body is with _____________.
RNA
water
DNA
macromolecules
The principal radiation interactions within the human body are assumed to be ________________.
DNA damage
direct effects
indirect effects
cell destruction
The two major parts of the cell are the nucleus and the ________________.
nucleolus
mitochondria
cell wall
cytoplasm
Tissues that are ____________ with a _______ metabolic rate are more radiosensitive.
immature; low
immature; high
mature; low
mature; high
Ameasure of the rate at which energy is transferred from ionizing radiation to soft tissue is know as
linear energy transfer
threshold dose
energy absorb dose
entrance skin exposure
In a linear threshold dose, any dose regardless of its size is expected to produce a response.
True
False
Humans are more radioresistant at birth.
true
false
In vitro refers to outside the body or outside the cell.
true
false
Radiation dose-response relationship is a mathematical relationship between various radiation dose levels and the magnitude of the observe response.
true
false
Which of these corollarries from law of Bergonie and Tribondeau are true
stem cells are radiosensitive
younger tissues and organs are radiosensitive
tissues with high metabolic activity are radiosensitive
Slow proliferation rate cells are more radiosensitive
What three major effects occur when macromolecules are irradiated in solution in vitro?
molecule synthesis
point lesion
cross-linking
main-chain scission
Catabolism is the process of breaking down large molecules into smaller molecules with a release of energy.
true
false
Synthesis of macromolecules from smaller molecules is referred as Metabolism.
true
false
The principal effect of radiation on humas is indirect effect.
true
false
When the ionizing event occurs on the target molecule, the effect of radiation is direct.
true
false
Principle that all plants and animals contain cells as their basic functional units
human radiation response
Human Body composition
cell theory
molecular composition
Organic molecules contain carbon.
hydrogen
carbon
oxygen
nitrogen
What is the most abundant molecule in the human body?
urea
DNA
water
mRNA
Proteins are made up of amino acids that provides structure and support to the human body.
True
false
Carbohydrates provide fuel for cell metabolism.
true
false
Deterministic is a theory that suggesting that all events, including moral choices, are completely determined by previously existing causes.
true
false
Acute radiation effects can also be referred as short term effect.
true
false
Acute Radiation Syndromes include:
hermatologic syndrome
gastrontestinal (GI) syndrome
central nervous system (CNS) syndrome
all of the above
Select the acute radiation lethality stages in order
Prodromal period, latent period, manifestation period
Manifestation period, latent period, prodromal period
latent period, prodromal period, manifestation period
prodromal period, manifestation period, latent period
Alethal whole-body radiation dose that causes 75% of irradiated subjects to die within 30 days can be define as:
Lethal Dose 75/30
Lethal Dose 30/75
Whole Body Exposure 75/30
Lethality 75/30
Shrinkage of an organ or tissue caused by cell death is defined as:
atrophy
desquamation
tissue decay
tissue damage
Damage to basal cells results in the long term manifestation of erythema.
true
false
A chromosome hit represents severe damage to the DNA.
true
false
Select the response curve describing the skin effects following a nonlinear, threshold dose.
A
B
C
D
Stochastic effects of radiation exposure are the result of low doses delivered over a long period.
TRUE
FALSE
At worst, humans can expect a reduced life of approximately 5 days for every 10 mGyt
true
false
Low-dose, chronic irradiation does impairs fertility.
true
false
The most radiosensitive period during pregnancy is
first trimester
second trimester
third trimester
fourth trimester
Radiation exposure in utero does retard the growth and development of the newborn.
true
false
Select the response curve descriving the genetic effects following linear, nonthreshold response.
A
B
C
D
A __________ effect increases in incidence but not severity as the dose increases.
stochastic
deterministic
localized
nonstochastic
Chronic low doses of radiation have ________ effect on fertility.
an increasing
a strong
a weak
no
Data showing radiation-induced human genetic abnormalities __________________.
indicates responses to high doses
. is being studied by the BEIR
does not exist
indicates responses to low doses
It is difficult to link cancer to radiation exposure because it occurs ___________ in the population.
in high proportion
very rarely
with severity
onlu in the elderly
Radiation protection guidelines are based on _______________________.
stochastic effects of radiation
stochastic and deterministic effects of radiation
deterministic effects of radiation
d. lethal effects of radiation
____________ is a stochastic effect of radiation exposure.
nausea
epilation
erythema
cancer
During the latent period, the radiation victim experiences _____________.
nausea and vomiting
hair loss
skin erythema
well-being
High doses of radiation to a localized area can lead to ____________ of tissues and organs in that area.
reduction in size
total loss of function
reduction in size, shrinkage, and total loss of function
shrinkage
The LD 50/60 is the dose of radiation to the whole-body that will result in death within __________ to _____% of the irradiated population.
60 days; 50
50 minutes; 60
60 minutes; 50
50 days; 60
There is usually a _______________ before the symptoms of acute radiation syndromes appear
loss of hair
latent period
recovery period
prolonged illness
