Which among the following statement is correct about ciclopirox?

1. AOC for cutaneous candidiasis

2. AOC for various Tinea infection

3. DOC for onychomycosis

Which among the following can inhibit squalene epoxidase?

Which among the following is an example of polyene antifungal antibiotics:

1. Griseofulvin           2. Nystatin   3. Natamycin             4.Amphotericin B

First orally active broad spectrum imidazole antifungal:

Which among the following does not belong the group?

The following limitations are associated with the use of polyenes, except:

1. good water solubility

2. it is nephrotoxic esp. amphotericin B

3. it chemically stable

Polyene antifungals possess conjugated double bonds, which among the following is/are correct?

For the treatment of systemic mycosis, which of the following antifungal agents can be administered by intravenous route?

Which among the following is true about 5-FU?

1. It can inhibit protein synthesis

2. It can inhibit DNA synthesis

3. It is activated from flucytosine by the help of cytosine permease

Which among the following fatty acid is found normally on perspiration as fungicidal agent?

The most common problem associated with the use of amphotericin B thus making it as the last option for systemic antifungal therapy is

An example of anti-fungal antibiotics:

Which of the following is considered the treatment of choice for Aspergillus infections in immunocompetent and immunocompromised patients?

Drug interactions can occur with all azoles but are LESS likely with which of the following drugs?

Which among the following is/are true about this structure:

1. it is an example of triazole antifungal

2. it is an example of imidazole antifungal agent

3. it possess piperazine ring

Griseofulvin must be given on a high fat meal.

Any substitution on the triazole or imidazole is allowed provided that an electron withdrawing group is present.

Benzoic acid is an example of antifungal that cannot penetrate the skin, hence effective in the management of topical fungal infection

Presence of an electron withdrawing group found on the aromatic ring enhances antifungal property of azole antifungals.

The salt form of fatty acid that can be used as antifungal are static in nature.

Skin is considered as a formidable barrier for drug penetration and absorption.

Undecylenic acid is a product of the destructive distillation of ricinoleic acid from castor oil.

To become an effective keratolytic agent, benzoic acid is not used with other drug so that it can enhances drug penetration.

The polyene antifungals can act as false membrane component.

Chemically speaking, terbinafine is not a true example of allylamine.

MOA or chemical classification: allylamine

MOA or Chemical Classification: triazole type

phenolic

nucleoside anti-fungal

polyene antifungal - antibiotic

sodium caprylate

caspofungin

terfenadine

Tinea capitis

Tinea cruris

Tinea corporis

Salicylic acid with resorcinol and benzoic acid can produce synergistic effect.

DOC: fungal meningitis