WorksheetsImmune system
Total questions: 60
Worksheet time: 42mins
The response to an infection. Causes the area to redden, swell, and feel warm.
Fever
Mucus
Dilation
Inflammation
Which is NOT considered FIRST line of defense?
Helper T-Cells
Skin
Hair
Mucous Membranes
The innate immune system is...
Always working and doesn't require any special preparation
Needs to be "primed" before it can work to its full effectiveness
Very specific and only defends against a specific pathogen
Not very effective at preventing intruders
This sticky fluid traps any pathogens that try and get in our body
Mucous Lining
Blood
Stomach Acid
Skin
Epitope is
antigen carrier molecule
antigen determinant site
Antibodies are
immunoglobulins
carbohydrates
lipids
Antibody structure is commonly
Z shaped
Y shaped
W shaped
T shaped
Antibody structure contains
One heavy and one light polypeptide chain
One heavy and two light polypeptide chain
Two heavy and one light polypeptide chain
Two identical heavy and two light polypeptide chain
Heavy chain and light chain in an antibody joint by
phosphate di ester bonds
Disulfide bonds
peptide bond
Antibodies divided into
two class
five class
ten class
three class
Types of immunoglobulins are
IgA, IgM, IgG, IgE and IgD
IgA and IgM only
IgD and IgG only
IgA only
IgM is
Monomer
Dimer
Trimer
Pentamer
IgG is
dimer
monomer
tetramer
pentamer
Major immunoglobulin in serum is
IgG
IgM
IgA
IgE
Antibody which can pass through placenta from mother to foetus is
IgE
IgM
IgD
IgG
Determine the main antibody that found in the mucus secretion
Ig A
Ig G
Ig M
Ig D
Which is the Immunoglobulin seen during allergy reaction?
Ig G
Ig E
Ig M
Ig D
What are the two types of the immune system?
Innate and adaptive immune systems
Primary and Secondary immune systems
Natural and flexible immune systems
Dendritic cells eat up harmful microorganisms via the process
Phagocytosis
Phagocytes
Phagocytose
What produce antibodies?
Helper T cells
B cells
Cytotoxic T cells
dendritic cells
Which of the following is part of innate immunity ?
macrophages
neutrophils
B cells
T cells
Which of the following antigens would bind to this B cell receptor?
Which of the following would best represent APC interactions?
Which of the following best describes the actions of cytotoxic T cells?
They secrete antibodies that are specific to the pathogen
They secrete granzymes and perforins that destroy the pathogen
They are involved in activating B cells
They are the clean-up crew after the infection.
Which part of the graph would represent a secondary response?
A
B
C
none of them
The response in “B” in the graph above could have been caused by which of the following?
The person was given a vaccine as a baby and then was exposed to measles later in life
The person was given their mom’s antibodies and they made antibodies from hers
The person was given antibodies from someone else and the person made their own.
“B” is the first response of the measles exposure.
What is the result of this interaction?
A T-cell is activated
The virus can't bind to and infect a cell
A B cell starts making antibodies
An antigen presenting cell will present its antigen
What is the main purpose of the MHC1 molecule?
to display antigens from pathogens it has engulfed from phagocytosis
to activate Helper T cells
to display endogenous antigens, either normal cell proteins or viral proteins
to bind to antibodies
What is this cell doing?
it is a normal body cell presenting a viral protein after being infected and presenting the antigen on its MHC1 molecule
it is an antigen presenting cell engulfing a virus, breaking it down, and presenting it on its MHC2 molecule
It is a B cell producing antibodies
It is a T cell being activated
In clonal selection of B cells, which of the following is responsible for determining which cells will eventually become cloned?
matching the correct antigen to the correct B cell
secretion of mucus
the production of antibody
the secretion of histamines
Which of the following best describes what happens next?
The antigenic determinant binds to the virus and neutralizes it
The antigenic determinant matches to B cell 2 and activates it, causing B cell 2 to divide rapidly
The antigenic determinant matches to all B cells and activates all of them, creating the B cell army
The antigenic determinant will bind to the infected cell and alert an antigen presenting cell
A person has lost the humoral/B cell activity in their immune system. What is one of the most detrimental results of this?
Infected cells can't be killed
antibodies can't be made
pathogens can't be engulfed
T cells can't be actviated
Many new treatments for diseases are being created using antibodies, such as cancer, lupus, Crohns, and rheumatoid arthritis. Many of them work by attaching to a molecule causing inflammation and blocking its action. Which of the following characteristics of antibodies allows researchers to use antibodies so successfully?
antibodies are proteins
Millions of antibodies are made
Antibodies are specific to their target
Antibodies last for a long time.
Regarding the antibodies as new medications,: The fact that these treatments usually involve a longterm treatment plan with the patient coming in every 6 – 8 weeks for an IV infusion means that this is
a passive immune treatment
an active immune treatment
a natural immune treatment
one that invokes memory cells
Which part of an antibody can attach to an antigen?
A
B
C
D
E
If, for some reason, the humoral branch of the immune system is unable to respond, what would be one possible effect of that loss?
no antibodies would be made
no T cells would be activate
no helper T cells would be activated
macrophages are activated
Antibody mediated immunity is called
Non specific immunity
Humoral immunity
innate Immunity
cell mediated immunity
The most prevalent antibody in serum
IgG
IgM
IgA
IgE
The immunoglobulin found in a mother's milk is
IgM
IgA
IgE
IgG
encapsulated bacteria are more efficiently phagocytized if they are coated with antibodies, It is called
Optimization
Inflammation
compliment fixation
immunization
The healthy human immune system responds to pathogens with both specific and nonspecific processes. Which of the following models represents a nonspecific response?
After an initial infection, B-cells recognize the measles virus. How is this helpful in human immune response?
The B-cells use this recognition to defend the body against other pathogens, such as bacteria.
The B-cells more quickly recognize and respond to any other virus that invades the body.
The B-cells produce antibodies more quickly if the measles virus is encountered again.
The B-cells transfer this recognition to T-cells, which will then devour the viruses.
What is an example of Artificial active immunity?
Vaccination
Natural infection
What do chemical barriers include?
Tears, breast milk, sweat, saliva, stomach acid
Tears, breast milk, sweat, stomach acid, and feces
Tears and urine
Hair, breast milk, sweat, saliva, stomach acid
What are the major types of cells of Adaptive (Specific) Immunity?
Natural Killer Cells
Neutrophils and Basophils
T cells and B cells
Eosinophils and Macrophages
Which type of immunity is transmitted from mother to child?
Artificial active immunity
Natural active immunity
Passive immunity
Mother immunity
