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Biology 1

Total questions: 87

Worksheet time: 1hrs 3mins

Name
Class
Date
1.

All cells carry the entire genome of an organism apart from:

a)

hair follicles and gametes.

b)

skin cells and gametes.

c)

gametes and red blood cells.

d)

gametes.

2.

Gene expression is the ability for a gene to be:

a)

in the genome.

b)

transcribed.

c)

non-coding.

d)

a dominant allele.

3.

Which RNA type is the result of transcription?

a)

tRNA

b)

Non-coding RNA

c)

rRNA

d)

mRNA

4.

Which of the following is correct?

a)

Nucleotide triplets code a single amino acid.

b)

Each amino acid codes a nucleotide.

c)

Each nucleotide codes an amino acid.

d)

Amino acid triplets code a single nucleotide.

5.

RNA substitutes uracil for which nucleotide?

a)

Adenine

b)

Cytosine

c)

Guanine

d)

Thymine

6.

Translation is a process where:

a)

a polypeptide sequence is produced from a sequence of rRNA codons.

b)

a polypeptide sequence is produced from a sequence of tRNA codons.

c)

a polypeptide sequence is produced from a sequence of mRNA codons.

d)

a DNA nucleotide sequence is used to produce mRNA codon sequence.

7.

Epigenetics modulates genetic expression:

a)

differently in each cell in the body.

b)

by altering the genome.

c)

in response to only intracellular processes.

d)

consistently throughout an individual's life.

8.

Transcription factors are produced by:

a)

coding DNA.

b)

structural genes.

c)

non-coding DNA and structural genes.

d)

non-coding DNA.

9.

Hox genes are the most powerful control on the morphology of animals. They do this by:

a)

being highly conserved.

b)

coding for the body plan.

c)

coding body segmentation.

d)

regulating transcription of other genes.

10.

Monozygotic twins can look different to one another because:

a)

they have different genetic material from the mother but the same genetic material from the father.

b)

they have different genetic material from the father but the same genetic material from the mother.

c)

the environment is determinative of phenotype.

d)

a mutation has occurred in one twin during embryonic development.

11.

A traumatic event experienced by an organism can affect the health of its children and grandchildren. This can happen through inherited:

a)

epigenetic tags.

b)

polypetide chains.

c)

transcription factors.

d)

DNA nucleotide patterns.

12.

A split gene includes non-coding introns that are ____________ during post-transcriptional modification.

a)

capped

b)

removed

c)

retained

d)

methylated

13.

DNA methylation patterns are generally:

a)

predictable

b)

substantially altered when an individual smokes.

c)

inherited from the parents.

d)

set early in embryonic development.

14.

The homeobox gene is highly conserved. This shows that:

a)

it is a sequence that is unlikely to mutate.

b)

its role in gene expression is vital to survival.

c)

it is coded for in several places.

d)

it is very powerful; therefore maintained by evolution.

15.

Gene regulation occurs:

a)

only in some cells.

b)

when the variability within the genetic code is insufficiently adaptive for the individual to survive in its environment.

c)

constantly, in all known life forms.

d)

during embryonic development.

16.
_______ is to transcription as ________ is to translation.
a)
mRNA / Amino Acid Chain
b)
Amino Acid Chain / mRNA
c)
Ribosome / Nucleus
d)
mRNA / tRNA
17.
Which of these processes begin with an mRNA molecule?
a)
DNA Replication
b)
Transcription
c)
Translation
d)
None of them
18.

Translation in eukaryotes occurs:

a)

outside of the nucleus.

b)

inside of the nucleus.

19.
What structure of this molecule binds with the mRNA molecule?
a)
Amino Acid
b)
tRNA
c)
Anticodon
d)
Codon
20.

The SRY gene codes for a transcription factor which:

a)

begins the process that turns a female foetus into a male foetus.

b)

ensures that development begins as a female foetus.

c)

ensures that development begins as a male foetus.

d)

begins the process that turns a male foetus into a female foetus.

21.

All the genes in both a prokaryotic cell and a eukaryotic cell are expressed at the same time.

a)

True

b)

False

22.

Prokaryotes regulate gene expression primarily

a)

in order to maintain homeostasis

b)

in response to changing environmental conditions

c)

during development as cells specialize

d)

Prokaryotes do not regulate gene expression. All genes are always on.

23.

One way to regulate the expression of a gene is to control the formation of mRNA. This is called ___ control.

a)

transcriptional

b)

translational

c)

post-transcriptional

d)

post-translational

24.

In order for a gene to be expressed, ___ must bind to the gene's ___, a specific sequence of nucleotides at one end of the gene, thus initiating transcription.

a)

DNA polymerase, promotor

b)

DNA polymerase, operator

c)

RNA polymerase, promotor

d)

RNA polymerase, operator

25.

An operon is

a)

a genetic on/off switch in prokaryotes

b)

a genetic on/off switch in eukaryotes

c)

a group of related genes and the associated gene switches in prokaryotes

d)

a group of related genes and the associated gene switches in eukaryotes

26.

Genes can be shut off (not expressed) when a ___ binds to the ____.

a)

activator, operator

b)

repressor, operator

c)

corepressor, operator

d)

repressor, promotor

27.

What molecule can remove a repressor protein from the operator?

a)

a corepressor

b)

an inducer

28.

What is the inducer in the lac operon?

a)

cAMP

b)

glucose

c)

lactose

d)

CRP

29.

Genes can be turned on (expressed) when a(n) ____ such as CRP or cAMP receptor protein binds to the CRP binding site.

a)

repressor

b)

corepressor

c)

inducer

d)

activator

30.

In the lac operon system, __ must first bind to CRP so that it is capable of binding to the DNA. This occurs when glucose levels are __.

a)

cAMP, high

b)

cAMP, low

c)

inducer, high

d)

inducer, low

31.

Negative control of gene expression is mediated by __ and results in a(n) __ in the frequency of transcription.

a)

activators, increase

b)

activators, decrease

c)

repressors, increase

d)

repressors, decrease

32.

In the trp operon, __ acts as a __ and helps the repressor bind to the operator.

a)

tryptophan, corepressor

b)

tryptophan, inducer

c)

lactose, corepressor

d)

lactose, inducer

33.

The trp operon has only ___ control which is common for the genes needed for ___ processes.

a)

positive, catabolic

b)

positive, anabolic

c)

negative, catabolic

d)

negative, anabolic

34.

Eukaryotes need to regulate their genes

a)

during cell specialization that occurs during development

b)

in order to maintain homeostasis

c)

both a and b

d)

neither a or b

35.

Which of the following is/are similarities between prokaryotic and eukaryotic gene expression?

a)

both use proteins to interact with the DNA to control gene expression

b)

both have histones complexed with their DNA

c)

both separate the processes of transcription and translation spatially

d)

all of the above

36.

___ are DNA sequences which are often located far from the genes they regulate in eukaryotes where transcription activators can bind.

a)

histones

b)

promotors

c)

enhancers

37.

Which of the following help to turn genes on so that they are expressed (transcribed and translated)?

a)

a high level of condensation (coiling around histones)

b)

histone acetylation

c)

DNA methylation

d)

histone methylation

38.

Inheritance NOT involving the nucleotide sequence of the DNA but involving chromatin modifications such as methylation is called

a)

epigenetic inheritance

b)

antigenetic inheritance

39.

Which of the following are types of post-transcriptional control of genes in eukaryotes?

a)

alternative RNA splicing or processing

b)

gene silencing through RNA interference

c)

destruction of ubiquitin tagged proteins

d)

all of the above

40.

Alternative RNA splicing involves

a)

removing introns and splicing the same exons together

b)

removing exons and splicing the same introns together

c)

removing introns and splicing different exons together

d)

removing exons and splicing different introns together

41.

The z gene codes for:

a)

permease

b)

beta-galactosidase

c)

repressor of lac operon

d)

transacetylase

42.

Operons are found in which of the following organisms?

a)

Bacteria(prokaryotes)

b)

plants and animals(eukaryotes)

c)

only animals

d)

virsuses

43.

An operon consists of all of the following except:

a)

operator

b)

regulatory gene

c)

promoter

d)

genes of the operon

44.

The y gene codes for:

a)

beta-galactosidase

b)

permease

c)

transacetylase

d)

repressor of lac operon

45.

The a gene codes for:

a)

Beta-galactosidase

b)

permease

c)

transacetylase

d)

repressor of lac operon

46.

The i gene codes for:

a)

transacetylase

b)

repressor of lac operon

c)

permease

d)

beta-galactosidase

47.

The cistrons in lac operon have a common promoter.

a)

True

b)

False

48.

The lac operon genes only become expressed if:

a)

lactose binds to repressor

b)

glucose binds to repressor

c)

repressor binds to operator

d)

lactose binds to operator

49.

A protein that binds to the operator and blocks the RNA polymerase:

a)

activator

b)

repressor

c)

regulator

d)

corepressor

50.

Beta-galactosidase is used for:

a)

hydrolysis of lactose

b)

inducing the lac operon

c)

represses the lac operon

d)

increase permeability to beta-galactosides

51.

The on/off switch for an operon is:

a)

gene

b)

operator

c)

promoter

d)

repressor

52.

What type of gene control is shown in this image?

a)

processing control

b)

transcriptional control

c)

post translational control

d)

mRNA stability control

53.
If this image were real, it would represent what type of inheritance?
a)
incomplete dominance
b)
codominance
c)
polygenic inheritance
d)
compete dominance
54.
A red flowered plant (RR) breeds with a White flowered plant (WW). The gene for petal color in these plants expresses incomplete dominance.  What percentage of the offspring will have pink (RW) flowers?
a)
0%
b)
25%
c)
50%
d)
100%
55.
What are the possible genotypes for this cross?
a)
TT = 25% Tt= 50% tt=25%
b)
all tall
c)
TT= 75% tt = 25%
d)
Tt = 100%
56.
If a gene is found only on the X chromosome and not the Y chromosome, it is said to be what?
a)
sex-linked trait
b)
polygenic trait
c)
codominant trait
d)
incomplete dominance trait
57.
Which of the following genotypes belongs in the red box in the Punnett square?
a)
XBXB
b)
XbXb
c)
XbY
d)
XBY
58.

What is the phenotype of a person with the genotype IAi?

a)
type A
b)
type O
c)
AA
d)
OO
59.

If two parents are heterozygous for type A blood , what is the probability that their offspring would have type O blood? Do the Punnett Square. Do not guess.

a)

100 %

b)

75%

c)

50%

d)

25%

60.
Universal blood donors have type ______ blood.
a)
A
b)
AB
c)
B
d)
O
61.
this image is an example of
a)
codominance
b)
dominance
c)
incomplete dominance
62.
Hemophilia is a recessive x-linked disorder.
Which genotype represents a female who is a carrier for hemophilia?
a)
XHXh
b)
XhXh
c)
XHXH
d)
XhY
63.

A condition in which both alleles for a gene are expressed so that both traits are visible is known as ---

a)

Codominance

b)

Incomplete dominance

64.

The blending of two traits is known as ---

a)

incomplete dominance

b)

codominance

65.

Codominance occurs in calico cats, which allows for the Black and Tan colors to show. What percentage of the offspring will be calico (black and tan spotted)?

a)

25

b)

50

c)

75

d)

100

66.

Incomplete dominance occurs in cats, which allows them to be Black, White, or gray as shown on this Punnett square. What percentage of the offspring will be black?

a)

25

b)

50

c)

75

d)

100

67.
What would indicate a normal human male?
a)
XX
b)
X
c)
XY
d)
XXY
68.

If a father has homozygous Type A blood and a mother has type AB, what is the probability for a child with AB blood? 

a)
0%
b)
25%
c)
50%
d)
75%
69.
If two parents are heterozygous for type A blood, what is the probability that their offspring would have type O blood?
a)
100 %
b)
75%
c)
50%
d)
25%
70.

In dogs, brown fur (B) is dominant over white fur (b). A homozygous dominant dog with brown fur is crossed with a heterozygous dog with brown fur. What are the percentages of the possible genotypes?

a)
100% BB
b)
75% BB and 25%Bb
c)
50 % BB and 50% Bb
d)
50% Bb and 50% bb
71.

What is a phenotype?

a)
The genetic make up (code)
b)
The physical trait
72.

 Which allele combination is heterozygous ?  

a)
Tt
b)
TT
c)

tt

73.

A blue flower is crossed with a red flower and you get a purple flower. Which pattern of inheritance is this?

a)

Incomplete Dominance

b)

Codominance

c)

Multiple Alleles

d)

Polygenic Inheritance

74.

If both traits are fully and equally expressed, one trait is __________ to the other.

a)

Dominant

b)

Codominant

c)

Incompletely Dominant

d)

Recessive

75.

Chickens with black feathers are crossed with chickens with white feathers. Their offspring have black and white feathers. Which pattern of inheritance is this?

a)

Codominance

b)

Incomplete Dominance

c)

Multiple Alleles

d)

Polygenic Inheritance

76.

Which of the following is not an allele for blood type?

a)

A

b)

B

c)

O

d)

i

77.

If you have type O blood, what is your blood genotype?

a)

Ai

b)

Bi

c)

OO

d)

ii

78.

If you have type a blood what is your blood genotype?

a)

AA

b)

Ai

c)

AB

d)

Aa

79.

Which blood type is the universal donor? (They can give blood to all other blood types)

a)

A

b)

B

c)

AB

d)

O

80.

Which blood type is the universal recipient? (They can receive any type of blood.)

a)

A

b)

B

c)

AB

d)

O

81.

Blood type is an example of which two (2) patterns of inheritance?

a)

Multiple Alleles & Codominance

b)

Polygenic Inheritance & Multiple Alleles

c)

Incomplete Dominance & Multiple Polygenic Inheritance

d)

Codominance & Incomplete Dominance

82.

A trait produced by two (2) or more genes is an example of...

a)

Polygenic Inheritance

b)

Multiple Alleles

c)

Codominance

d)

Incomplete Dominance

83.

What is epistasis?

a)

When one gene controls the others

b)

When one gene is recessive to the others

c)

When one gene is codominant to another

d)

When there are multiple alleles for one gene

84.

Why are linked genes not always inherited together?

a)

Crossing over occurs during meiosis

b)

The chromosomes separate during anaphase

c)

Linked genes are on different chromosomes

d)

Genes are always inherited independently

85.

If someone is a biological male, what are their sex chromosomes?

a)

XX

b)

XY

c)

AB

d)

23

86.

Why does the X-Chromosome affect more traits than the Y-Chromosome?

a)

X chromosome is smaller than the Y chromosome

b)

X chromosome is larger than the Y chromosome

c)

X chromosome is dominant to the Y chromosome

d)

X and Y chromosomes are incompletely dominant

87.

Why will males always express the recessive version of an x-linked trait?

a)

Males have 2 X chromosomes

b)

Males only have 1 X chromosome

c)

Male chromosomes are always incompletely dominant

d)

Males have more chromosomes