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3.1 Genes

Total questions: 24

Worksheet time: 39mins

Name
Class
Date
1.

What determines the genomic size of a species?

a)

The total amount of DNA

b)

The total number of genes

c)

The total number of alleles

d)

The total number of chromosomes

2.

What is the cause of sickle-cell anemia?

a)

A change to the base sequence of a hemoglobin gene

b)

Mosquitos acting as the vector for malaria

c)

Iron deficiency due to the malaria parasite

d)

Production of more white blood cells than red blood cells by bone marrow

3.

Which of the following is the cause of sickle-cell anemia?

a)

Tryptophan is replaced by leucine

b)

Leucine is replaced by valine

c)

Glutamic acid is replaced by valine

d)

Lysine is replaced by glutamic acid

4.
What is the name given to part of a DNA molecule that codes for a protein?
a)
Glucose
b)
Chromosome
c)
Gene
d)
Phosphate
5.

What distinguishes an allele from a gene?

a)

An allele is made of RNA

b)

An allele is shorter

c)

An allele is a variety of a gene

d)

An allele cannot be transferred during genetic modification

6.
Genes are made of a pair of ____
a)
DNA
b)
Chromosome
c)
Alleles
d)
Phenotype
7.

Which statement correctly describes genome and proteome?

a)

Only the genome but not the proteome can be analysed using gel electrophoresis.

b)

The genome and the proteome are the same in all tissues in an organism.

c)

In cells of different tissues, the genome is the same while the proteome varies.

d)

Only mutations in the proteome but not in the genome cause any variability

8.
Genes are made of a pair of ____
a)
DNA
b)
Chromosome
c)
Alleles
d)
Phenotype
9.

A genome is.....

a)

the total of all the genetic information an organism has

b)

the number of chromosomes an organism has

c)

the mechanism by which an individual passes on genetic information

d)

a small garden statue belonging to a frenchman

10.
How can the change of one base in a gene sequence completely change the protein it codes for?
a)
Protein shape is specific to the primary sequence of the amino acids it is comprised of
b)
One change of base is not enough to change the shape or effectiveness of a protein
c)
The change in the gene sequence results in the resulting enzyme being denatured at a lower temperature
d)
Proteins are comprised of polysaccharide monomers which are sensitive to changes in DNA
11.
What is the primary cause of the conformational change in the hemoglobin of individuals with sickle cell anemia?
a)
A single base substitution results in glutamic acid being replaced by valine during translation
b)
Low concentrations of oxygen causes normal red blood cells to change shape
c)
Individuals lack iron in their diet which causes them to be anemic
d)
The individual is completely lacking the gene to code for hemoglobin
12.

True or false, the number of genes is determined by the complexity of the organism?

a)
b)
13.

Each gene occupies a specific position on a specific chromosome, this position is referred to as....

a)

the locus

b)

the centromere

c)

the allele

d)

the proteome

14.

Which molecules make up a eukaryotic chromosome?

a)

DNA & RNA

b)

DNA & Protein

c)

DNA, RNA, & Protein

d)

DNA, RNA, & Carbohydrate

15.

Which of the following answers are TRUE? (2)

a)

The genome of prokaryotes is much smaller and consists of a circular chromosome

b)

The genome of both prokaryotes and eukaryotes consist of chromosomes comprised of DNA coiled around histones

c)

The genome of humans consists of 46 molecules, whereas the genome of prokaryotes consists of one molecule plus any plasmids present

d)

Plants do not have a genome

e)

A genome refers only to the portions of DNA that contain genes

16.

What type of mutation causes sickle cell anemia?

a)

Base substitution

b)

Base deletion

c)

Base insertion

d)

All of these types of mutation

17.

How are new alleles formed?

a)

By random mutation

b)

By pre-determined mutation

c)

During protein synthesis

d)

New alleles can never be formed

18.
Which sentence is FALSE?
a)
All organisms have 23 pairs of DNA.
b)
Chromosomes are made of genes.
c)
DNA is made out of 4 chemicals: adenine, cytosine, thymine, guanine
d)
DNA is the recipe for life.
19.
Which of the following changes in DNA is likely to have the greatest effect on the resulting peptide? 
a)
 a “G” is inserted at the end of a gene 
b)
in a strand of DNA, one T is changed to a C
c)
in a strand of DNA, one C is changed to a T
d)
a “G” is inserted at the beginning of a gene
20.
What is the set of alleles that an individual possesses?
a)
Gene
b)
Genotype
c)
Genome
d)
Genus
21.

What are the units of heredity responsible for influencing our traits (characteristics)?

a)

proteins

b)

ribonucleic acid

c)

genes

d)

hormones

22.

Which of the following conditions makes a person a carrier of sickle cell anaemia?

a)

having two normal versions of the HBB gene

b)

have one normal and one faulty version of the HBB gene

c)

having two faulty versions of the HBB gene

d)

having no HBB gene at all

23.

Which one of the following is incorrect about the effects of sickle cell anaemia?

a)

higher frequency of blood clotting

b)

irregular blood flow

c)

lower oxygen carrying capacity

d)

lower resistance to malaria

24.
A human cell has between 20,000-25,000 genes whereas an E. coli cell has approximately 4,000 genes.  Which of the following statements is true?
a)
The human genome is larger than the E. coli genome
b)
There are more genes on each human chromosome than on the E. coli chromosome
c)
The human cell and the E. coli cell produce approximately the same variety of proteins
d)
The DNA in both organisms is associated with histones (proteins)