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WorksheetsNDDS-01
Total questions: 16
Worksheet time: 8mins
One of the following is not an advantages of NDDS.
Patient Compliance
Steady State Plasma Conentration
Less drug of dose
Chance of dose dumping
One of the following is not a type of CDDS
Rate-programmed DDS
Stimuli-activated DDS
Site-targeted DDS
None of the above
Correct statement regarding an Ocusert system is
it is a tablet taken orally
it is meant to be insert in cul-de-sac cavity
It is example of Osmotic DDS
It is example of Transdermal DDS
Which of the osmogen used in an osmotic controlled drug delivery system
Sodium chlorid
Propylene glycol
Poly vinly acetate
Polly vinyl pyrollidone
Mainly drugs are absorbed through skin by one of the processes
Passive diffusion
Active tranport
Filteration
Carrier transport
Chose the drawback of using CDDS
Prompt termination of therapy is not possible
Prevention of side effects
Risk of dose dumping
Maintenance of drug levels within a desired range
Following are the physiological (Physicochemical) factors affecting on CDDS, except
Aqueous solubility
Drug pKa
Biological Half-life
§Protein binding
The rate-limiting steps for the controlled release dosage form
Dissolution
Drug release from the dosage form
Drug absorption
Drug penetration
A good drug candidate for controlled drug delivery should have half-life of
2-6 hr
8-12 hr
Less than 2 hr
More than 24 hr
___________selected to release the drug in controlled manner, at a predetermine rate and predetermine time.
Orally disintegrating drug delivery system
Fast drug delivery system
Immediate release DDS
Controlled DDS
OROS is a technology developed for
Oral release rapid onset system
Transdermal drug delivery system
Osmotic controlled oral controlled drug delivery system
Orally rapid disintegrating tablets
The drug release form OSDDS (Osmotic Pump) is
First order
Zero order
Mix order
Pseudo first order
The pKa range for an acidic drug that ionization depends on the pH range is
1.0 to 3.0
3.0 to 7.5
7.0 to 11.0
9.0 to 14.00
Drugs showing high plasma protein binding
Not a good candidate for CRDDS
A very good candidate for CRDDS
Can not be used for any drug delivery system
None of the above statements is suitable
The ideal molecular size of a drug candidate for CDDS is
200 D
4000 D
600 D
1200 D
Full Name of TR formulation is (a)
