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WorksheetsRespiratory Exam 1: Jones - Review
Total questions: 84
Worksheet time: 3600secs
Which type of alveolar cells secrete surfactant?
Type I
Type II
Type III
None
T or F: The parietal pleura covers the surface of the lungs.
True
False
As the diaphragm contracts during inspiration, the Intrapulmonary Pressure (Pip) ________.
increases
decreases
does not change
As the amount of surfactant in the lungs increases, the lung compliance _______.
increases
decreases
does not change
T or F: Contraction of the internal intercostal muscles expands the thoracic cavity.
True
False
The maximum amount of gas that can be inspired after a normal tidal expiration is the:
Inspiratory Capacity
Tidal Volume
Inspiratory Reserve Volume
Residual Volume
T or F: Sympathetic agonists could be utilized to treat asthma.
True
False
T or F: The partial pressure of oxygen decreases at high altitude because the amount of oxygen in the air is decreased.
False
True
T or F: Breathing 100% oxygen will increase the total oxygen content of whole blood by 5 times.
False
True
Arterial blood pH is _______ proportional to the partial carbon dioxide pressure of arterial blood.
directly
indirectly
not
Central chemoreceptors respond to changes in:
Carbon Dioxide
Oxygen
Both
Neither
Which of the following are parts of the conducting zone?
Primary Bronchi
Trachea
Nose
Terminal Bronchioles
Respiratory Bronchioles
Which of the following are parts of the Respiratory Zone?
Respiratory Bronchioles
Alveolar ducts
Alveolar sacs
Terminal Bronchioles
What are the functions of the conducting zone?
Filtering the air
Cleaning the air
Warming the air
Humidifying the air
Gas exchange
During expiration, Intrapleural Pressure ________
decreases
increases
remains unchanged
During inspiration,
Alveolar pressure exceeds atmospheric pressure
Transpulmonary pressure increases
the diaphragm relaxes
intrapulmonary pressure is less than atmospheric pressure
The pressure of a given quantity of gas is inversely proportional to its volume.
Boyle's Law
Charles' Law
Dalton's Law
Henry's Law
A measure of the distensibility of the lungs is:
Compliance
Elasticity
Surface tension
The tendency of the lungs to return to their initial size after stretching is:
compliance
elasticity
surface tension
The pressure in a small alveolus is greater than a large alveolus as long as the surface tension is equal:
Boyle's Law
Dalton's Law
Laplace's Law
Henry's Law
Quiet expiration is caused by:
Contraction of the external intercostals
Contraction of the internal intercostals
Lung recoil
Increased intrapulmonary pressure
Contraction of the scalenes
Quiet inspiration will ______ thoracic and lung volume and ______ intrapulmonary pressure.
increase, increase
increase, decrease
decrease, increase
decrease, decrease
Which of the following are true?
Blood in the pulmonary veins is low in oxygen
Blood in the pulmonary veins is high in carbon dioxide
The oxygen concentration of inspired air is higher than that of alveolar air
All are true
The volume of gas inspired or expired in a quiet respiration cycle is the
tidal volume
vital capacity
inspiratory reserve volume
residual volume
The total amount of gas in the lungs after a maximum inspiration is the
vital capacity
total lung capacity
tidal volume
functional residual capacity
The amount of a given gas dissolved in the blood:
is directly proportional to the partial pressure of the gas
is indirectly proportional to the partial pressure of the gas
increases at higher altitudes
is described primarily by Boyle's Law
Normal arterial Po2 is
90 mmHg
100 mmHg
50 mmHg
190 mmHg
Normal venous Pco2 is:
40 mmHg
46 mmHg
100 mmHg
86 mmHg
The ventilation/perfusion ratio:
is lowest at the apex of the lungs
increases when blood flow is decreased
decreases when ventilation is increased
increases due to dilation of the pulmonary arterioles
Blood flow is greatest at the ____ of the lungs and perfusion is greatest at the ____ of the lungs.
apex, apex
apex, base
base, base
base, apex
Peripheral chemoreceptors that can detect changes in blood pH are located in the:
medulla oblongata
aortic and carotid bodies
pons
lungs
The primary drive to breath is elicited by which of the following:
reduced Po2
reduced Pco2
increased Po2
increased Pco2
What is the condition of having low blood oxygen levels?
hypoxemia
hypoxia
hypercapnia
hypocapnia
The dorsal respiratory group in the medulla oblongata is involved with
inspiration
expiration
breathing rhythm
both inspiration and expiration
Hyperventilation is stimulated by
increased activity of the apneustic center
decreased contraction of the scaleness
hypercapnia (high carbon dioxide)
hypoxemia
Carbon monoxide is lethal because it
reduces CO2 and slows breathing
increases CO2 and causes seizures
binds hemoglobin preventing oxygen binding
increases oxygen at the cells
The affinity of hemoglobin for oxygen is _____ as the partial pressure of oxygen is raised.
increased
decreased
remains unchanged
The Bohr effect:
describes the effect of pH on the affinity of hemoglobin for oxygen
describes the effect of pH on the affinity of hemoglobin for carbon dioxide
describes the mechanism of ventilation
describes the effect of solubility on the amount of gas dissolved in blood
A decrease in temperature will shift the oxygen dissociation curve to the
right
left
no change
An increase in 2,3-diphosphoglyceric acid (2,3-DPG) will _____ the affinity of hemoglobin for oxygen.
increase
decrease
no change
Which of the following will decrease the affinity of hemoglobin for oxygen?
decreased pH
increased temperature
increased 2,3-DPG
The exchange of chloride ions for bicarbonate through tissue capillaries is called the
Chloride shift
Bohr effect
Oxygen Toxicity
Acidosis
The majority of carbon dioxide is transported in the blood as
dissolved carbon dioxide
bicarbonate ion
carbaminohemoglobin
carboxyhemoglobin
Carbon dioxide ____ oxygen unloading and oxygen unloading ____ carbon dioxide transport.
increases, improves
increases, worsens
decreases, improves
decreases, worsens
What are the functions of the respiratory system?
Gas Exchange
Maintain blood pH
Speech/Sensory
Hormone Activation
Clot dissolution
Where does most gas exchange take place?
Alveolar ducts
Alveolar sacs
Trachea
Terminal Bronchioles
What muscles are utilized during Inspiration - Quiet Breathing?
Diaphram
External Intercostals
Internal Intercostals
Scalene
When the volume in the lungs decreases -->
Pressure decreases
Pressure increases
Change in Patm
Decreased air flow
T or F: Flow = Change in Pressure/Resistance
True
False
Change in Pressure = Palv-Patm
Change in Pressure = Patm-Palv
Inspiration:
Expansion of the chest
Compression of the chest
Pip decreases
Ptp increases
Palv becomes subatmospheric
Expiration:
Expansion of the chest
Compression of the chest
Pip becomes less negative
Palv becomes greater than Patm
Ptp moves back toward pre inspiration value
Increased Compliance
Floppy Lungs
Decreased Compliance
Fibrinolytic Lungs
Lung Volume on Y Axis
Transpulmonary Pressure on X Axis
Compliance is:
Change in Lung Volume/(Palv-Pip)
How easily the lungs can expand their volume for a given change in Ptp
Less Compliant = Stiffer lungs, not as much air
Alveoli that are already expanded will have less compliance
T or F: Surfactant reduce surface tension which causes alveolar collapse.
False
True
What is airway resistance dependent on?
Diameter of the Bronchioles
Compliance
Surface Tension
Surfactant
What is the correct equation for airway resistance?
R=length*viscosity/radius^4
R=length*viscosity/radius^2
R=length*viscosity/radius
R=length*radius^4/viscosity
Define alveolar ventilation:
Amount of fresh air which reaches the alveoli each minute
Amount of fresh air which reaches the alveoli each second
Amount of air which leaves the alveoli each minute
Amount of air which leaves the alveoli each second
Volume of air inhaled and exhaled during a breathing cycle
Tidal Volume (TV)
Amount of air which can be inhaled with maximal effort
Inspiratory Reserve Volume (IRV)
Amount of air which can be maximally exhaled
Expiratory Reserve Volume (ERV)
Amount of air left in the lungs following a maximal expiration
Residual Volume (RV)
IRV + TV + ERV; The total volume of air which can be inhaled and exhaled from the lungs
Vital Capacity (VC)
IRV + TV
Inspiratory Capacity (IC)
RV + ERV; Amount of air in the lungs following expiration/normal breathing
Functional Residual Capacity (FRC)
RV + FRC; About 6L; Amount of air we move maximally into and out of the lungs
Total Lung Capacity (TLC)
How do you calculate total dead space?
Vd = Tidal Volume - (PEco2*TV)/Paco2
Vd = Tidal Volume - (Paco2*TV)/PEco2
Vd = (PEco2*TV)/Paco2- Tidal Volume
Vd = (Paco2*TV)/PEco2 - Tidal Volume
How do you calculate Alveolar Ventilation?
Va = f(Tidal Volume-Dead Space Volume)
f = breaths/minute
21%
Oxygen
0.04%
Carbon Dioxide
(760-47)*21%=150 mmHg
Inspired Oxygen
100 mmHg
Alveolar Air Oxygen
40 mmHg
Alveolar Air Carbon Dioxide
Bronchiole: Dilate
Pulmonary Arteriole: (constrict)
Systemic Arteriole: dilate
Increased Carbon Dioxide
Bronchiole: constrict
Pulmonary Arteriole: (dilate)
Systemic Arteriole: constrict
Decreased Carbon Dioxide
Bronchiole: (constrict)
Pulmonary Arteriole: dilate
Systemic Arteriole: constrict
Increased Oxygen
Bronchiole: (dilate)
Pulmonary Arteriole: constrict
Systemic Arteriole: dilate
Decreased Oxygen
Low blood flow; Small amounts of ventilation
Apex
High blood flow; high amounts of ventilation
Base
Answer 3
Answer 3
What factors determine the diffusion of Oxygen and Carbon Dioxide?
Thickness
Surface area
Molecular weight
Lipophilicity
Describe the transport of Oxygen:
Oxygen is dissolved in plasma
Binds to Hb
Transported to Cells
D
Remaining Oxygen is dissolved
Right Curve Shift
Decreased affinity for O2 --> More unloading at tissues
Left Curve Shift
Increased affinity for O2 --> Less unloading at tissues
PO2
Determines binding affinity
Transport Mechanism for CO2:
Cellular respiration in peripheral tissues
Dissolved CO2 or Bound to Hb in RBC
Becomes HCO3- or Transported to Lungs
Dissolved CO2
T or F: The Bohr effect is an increase in Oxygen that will lead to a decrease of CO2 binding to Hb
True
False
Contract Peripheral and Central Chemoreceptors:
Peripheral Chemoreceptors - Activated by low O2, Increased CO2, Low pH
Central Chemoreceptors - Activated by low O2, Increased CO2, Low pH
Peripheral Chemoreceptors - Activated by increased CO2
Central Chemoreceptors - Activated by increased CO2
Stretch Receptors:
Reflex: Inspiration off, bronchodilation, tachycardia
Smooth muscle of bronchioles and visceral pleura
Free nerve endings in epithelial cells
Reflex: Bronchiole constriction, shallow breathing, coughing, prolonged inspiration
Irritant:
Reflex: Inspiration off, bronchodilation, tachycardia
Smooth muscle of bronchioles and visceral pleura
Free nerve endings in epithelial cells
Reflex: Bronchiole constriction, shallow breathing, coughing, prolonged inspiration
What is Valsalva Maneuver?
A breathing technique -- unclogs ears, restores heart rhythm
Increases Intrathoracic Pressure
Decreases Intrathoracic Pressure
Reduction in Preload -- Reduce Heart Rate
Lower blood pressure
Which of the following are examples of Obstructive Diseases?
Asthma (Wall Thickens)
Emphysema (Tissue damage, loss of traction)
Chronic Bronchitis (Blocked lumen, excessive secretion)
Increased Fibrosis (Thickening of alveolar interstitial wall)
Review this anatomy
Yes
No
Match the following lung pressures
Normal Lungs at Rest
Normal Lungs Mid Inspiration
Normal Lungs during Peak Inhalation
Which line represents a pH increase?
Red
Black
Blue
Green
Yellow
Which line represents anemia?
Red
Black
Blue
Green
Yellow
Which line represents a higher affinity for oxygen with decreased binding quantity?
Red
Black
Blue
Green
Yellow
Which line represents the body during exercise?
Red
Black
Blue
Green
Yellow
Which line represents fetal hemoglobin?
Red
Black
Blue
Green
Yellow
Prebotzinger
Pacemaker of the respiratory system is located here
PRG (Pontine)
Regulates the actions medulla respiratory centers
VRG
Neurons from this region contact muscle used for inspiration and expiration
DRG
Neurons from this region regulate diaphragm contraction during quiet inspiration
Determine the effect each of the following will have on alveolar ventilation?
Decreased PCO2 to 35 mmHg
Decrease
Decreased PO2 to 90 mmHg or Decreased Hemoglobin (anemia)
No change
Decreased PO2 to 50 mmHg
Increase
Match the pressures in the locations indicated during the respiratory cycle with the normal expected value.
Transpulmonary pressure in a resting lung at sea level
5
Atmospheric pressure during expiration
0
Alveolar pressure during mid expiration of a quiet expiration
1
Intrapluearal pressure during a forced inspiration
-12
