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Biochem Exam IV Review_Fall 2022: Max and Serena

Total questions: 45

Worksheet time: 26mins

Name
Class
Date
1.

Whithout considering any modifications, which of these lipid classes are hydrophobic and cannot form micelles?

a)

Triglycerides

b)

Phospholipids

c)

Waxes

d)

Fatty acids

2.

Unlike phospholipids, cholesterol is Not part of eukaryotic membranes.

a)

True

b)

False

c)

Cholesterol is a social construct, and therefore does not exit

3.

While a sphongosine group can be part of phospholipids, this is not the case for glycolipids.

a)

True

b)

False

c)

What even is a glycolipid?

4.

Essentially, hydrophobic interactions drive double-layer membrane formation.

a)

True

b)

False

5.

Relatively speaking, steroids are more polar than sterols.

a)

True

b)

False

6.

Which vitamins are hydrophobic? Selet all that apply.

a)

B

b)

C

c)

E

d)

K

7.

A membrane fluidity is largely determined by the percentage of...

a)

Phosphatidylcholine

b)

Unsaturated fatty acids

c)

Isoprene linked glycoproteins

d)

Phsophatidylserine

8.

Which of the following is generally Not a membrane lipid?

a)

Sphingolipid

b)

Cholesterol

c)

Triglycerides

d)

Phsophatidylserine

9.

Glycerol 3-phosphate is an intermediate of glycolysis

a)

True

b)

False

10.

Which fatty acid will be most water-soluble?

a)

Monoacylglycerol

b)

Diacylglycerol

c)

Triacylglycerol

d)

They are all the same

11.

NSAIDs block the production of leukotrienes and lipoxin from arachidonic acid.

a)

True! I literally took Advil this morming

b)

False! I can read the back of the pill bottle

12.

Which of these are eicosanoids? Select all that apply.

a)

Prostaglandins

b)

Prostacyclins

c)

Thromboxane

d)

Leukotriene

13.

Which of these pairs are incorrect? Select all that apply.

a)

Vitamin A: pigment

b)

Vitamin E: hydrophilic

c)

Vitamin K: hydrophobic

d)

Uncatalyzed transbilayer diffusion

14.

Lipid rafts are enriched in signaling proteins and receptors.

a)

True

b)

False

15.

Where does fatty acid synthesis primarily occur?

a)

Adipocytes

b)

Brain

c)

Liver

d)

Muscles

e)

Lung

16.

Which of these reactions provides the NADPH used for fatty acid synthesis?

a)

Citrate synthesis

b)

Beta oxidation of fatty acid

c)

Gluconeogenesis

d)

Conversion of cytoplasmic malate to pyruvate

e)

Conversion of mitochondrial matrix malate to OAA

17.

Acetyl CoA is the only building block required for fatty acid synthesis.

a)

True

b)

False

18.

Which of the statements below is true about malonyl CoA? Select all that apply.

a)

Inhibits beta oxidation

b)

Promotes beta oxidation

c)

Inhibits fatty acid synthesis

d)

Promotes fatty acid synthesis

19.

How many units of isoprene are required to form 30 carbon squalene molecules

a)

1

b)

3

c)

4

d)

6

e)

A whole bunch for sure

20.

Which of these promotes HMG CoA reductase activity?

a)

Glucagon

b)

Cholesterol

c)

Insulin

d)

AMPK

21.

Which of the following compounds could have their synthesis inhibited if HMG CoA reductase is inhibited?

a)

Testosterone

b)

Cholesterol

c)

Bile salts

d)

Ubiquinone

22.

Fatty acids are broken down in the cytosol.

a)

True

b)

False

23.

The most dense lipoprotein is

a)

HDL

b)

LDL

c)

VLDL

d)

Chylomicrons

24.

Phosphatidic acid is involved in the biosynthesis of cholesterol.

a)

True

b)

False

25.

Fatty acids use the malate shuttle to move from the cytosol to the mitochondrial matrix

a)

True

b)

False

26.

Which of these two is an intermediate in glycolysis?

a)

Glycerol-3-Phosphate

b)

Glyceraldehyde 3-phosphate

27.

Triglycerides are more efficient than glycogen at energy storage

a)

True

b)

False

28.

An omega -6 fatty acid has 20 carbons in total and three double bonds in its structure. With C1 being the carbon with carboxylic group, the first double bond of this mysterious omega-6 fatty acid is located ....

a)

Between C6 and C7

b)

Between C20 and C19

c)

Between C15 and C14

d)

Between C5 and C6

29.

22:1 delta 19 is an omega-3 fatty acid.

a)

True

b)

False

30.

Which is a glycerophospholipid? Select all that apply.

a)

Cardiolipin

b)

Phosphatidylcholine

c)

Phosphtidylinositol

d)

Phosphatidylserine

31.

Phospholipase A1 and D will generate the same products

a)

True

b)

False

32.

Match the disease with the symptom.

a)

Krabbe: hepatosplenomegaly

b)

Tay-sach: Neuronal cell death

c)

Gaucher: Hepatosplenomegaly

33.

Bile acids are derived for phospholipids, and they help emulsify lipids for a better absorption in the intestine.

a)

True

b)

False

34.

Which of these enzyme helps activate fatty acids?

a)

Carnitine acyltransferase 1

b)

Carnitine acyltransferase 2

c)

Fatty acylCoA Synthetase

d)

AcylCoA acetyltransferase

35.

The rate limiting step of beta oxidation is catalyzed by

a)

AcylCoA dehydrogenase

b)

EnoylCoA hydratase

c)

Fatty AcylCoA synthetase

d)

Carnitine Acyl transferase 1

36.

Beta oxidation can occur in which of these organelles? Select all that apply

a)

Lysosomes

b)

mitochondria

c)

peroxisome

d)

Endoplasmic reticulum

37.

Which of these enzymes is/are involved in beta oxidation in the peroxisome? Select all that apply

a)

Catalase

b)

AcylCoA reductase

c)

AcylCoA oxidase

d)

Fatty acylCoA synthetase

38.

Which is Not a ketone body?

a)

Acetoacetate

b)

Acetone

c)

D-b-hydroxybutyrate

d)

All of these options are ketone bodies

39.

The rate limiting enzymes for ketone bodies synthesis is...

a)

HMG CoA reductase

b)

HMG CoA Synthase

c)

HMG CoA Lyase

d)

Acetoacetate decarboxylase

e)

b-Hydroxybutyrate dehydrogenase

40.

Diabetes can be accompanied by ketoacidosis.

a)

True

b)

False

41.

Find the good matches (select all that apply).

a)

Beta oxidation: cytosol

b)

Fatty acid synthesis: NAD/FAD

c)

Fatty acid synthesis: enzyme-bound SH groups

d)

Fatty acid synthesis: NADPH

42.

The rate limiting step of fatty acid synthesis is catalyzed by

a)

Fatty acid synthase

b)

Acetyl CoA carboxylase

43.

Which of these processes is glycerol kinase involved in?

a)

Fatty acid synthesis

b)

TGA synthesis

c)

TGA catabolism

d)

Glycerophospholipid synthesis

44.

Under low concentrations of sterols in the ER, where is the regulatory region of SREBP located?

a)

ER membrane

b)

Proteasome

c)

Insing

d)

Nucleus

45.

Which enzyme is inhibited by the statins?

a)

HMG CoA synthase

b)

HMG CoA reductase

c)

Thiolase

d)

Mevalonate kinase