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WorksheetsBiochem Exam IV Review_Fall 2022: Max and Serena
Total questions: 45
Worksheet time: 26mins
Whithout considering any modifications, which of these lipid classes are hydrophobic and cannot form micelles?
Triglycerides
Phospholipids
Waxes
Fatty acids
Unlike phospholipids, cholesterol is Not part of eukaryotic membranes.
True
False
Cholesterol is a social construct, and therefore does not exit
While a sphongosine group can be part of phospholipids, this is not the case for glycolipids.
True
False
What even is a glycolipid?
Essentially, hydrophobic interactions drive double-layer membrane formation.
True
False
Relatively speaking, steroids are more polar than sterols.
True
False
Which vitamins are hydrophobic? Selet all that apply.
B
C
E
K
A membrane fluidity is largely determined by the percentage of...
Phosphatidylcholine
Unsaturated fatty acids
Isoprene linked glycoproteins
Phsophatidylserine
Which of the following is generally Not a membrane lipid?
Sphingolipid
Cholesterol
Triglycerides
Phsophatidylserine
Glycerol 3-phosphate is an intermediate of glycolysis
True
False
Which fatty acid will be most water-soluble?
Monoacylglycerol
Diacylglycerol
Triacylglycerol
They are all the same
NSAIDs block the production of leukotrienes and lipoxin from arachidonic acid.
True! I literally took Advil this morming
False! I can read the back of the pill bottle
Which of these are eicosanoids? Select all that apply.
Prostaglandins
Prostacyclins
Thromboxane
Leukotriene
Which of these pairs are incorrect? Select all that apply.
Vitamin A: pigment
Vitamin E: hydrophilic
Vitamin K: hydrophobic
Uncatalyzed transbilayer diffusion
Lipid rafts are enriched in signaling proteins and receptors.
True
False
Where does fatty acid synthesis primarily occur?
Adipocytes
Brain
Liver
Muscles
Lung
Which of these reactions provides the NADPH used for fatty acid synthesis?
Citrate synthesis
Beta oxidation of fatty acid
Gluconeogenesis
Conversion of cytoplasmic malate to pyruvate
Conversion of mitochondrial matrix malate to OAA
Acetyl CoA is the only building block required for fatty acid synthesis.
True
False
Which of the statements below is true about malonyl CoA? Select all that apply.
Inhibits beta oxidation
Promotes beta oxidation
Inhibits fatty acid synthesis
Promotes fatty acid synthesis
How many units of isoprene are required to form 30 carbon squalene molecules
1
3
4
6
A whole bunch for sure
Which of these promotes HMG CoA reductase activity?
Glucagon
Cholesterol
Insulin
AMPK
Which of the following compounds could have their synthesis inhibited if HMG CoA reductase is inhibited?
Testosterone
Cholesterol
Bile salts
Ubiquinone
Fatty acids are broken down in the cytosol.
True
False
The most dense lipoprotein is
HDL
LDL
VLDL
Chylomicrons
Phosphatidic acid is involved in the biosynthesis of cholesterol.
True
False
Fatty acids use the malate shuttle to move from the cytosol to the mitochondrial matrix
True
False
Which of these two is an intermediate in glycolysis?
Glycerol-3-Phosphate
Glyceraldehyde 3-phosphate
Triglycerides are more efficient than glycogen at energy storage
True
False
An omega -6 fatty acid has 20 carbons in total and three double bonds in its structure. With C1 being the carbon with carboxylic group, the first double bond of this mysterious omega-6 fatty acid is located ....
Between C6 and C7
Between C20 and C19
Between C15 and C14
Between C5 and C6
22:1 delta 19 is an omega-3 fatty acid.
True
False
Which is a glycerophospholipid? Select all that apply.
Cardiolipin
Phosphatidylcholine
Phosphtidylinositol
Phosphatidylserine
Phospholipase A1 and D will generate the same products
True
False
Match the disease with the symptom.
Krabbe: hepatosplenomegaly
Tay-sach: Neuronal cell death
Gaucher: Hepatosplenomegaly
Bile acids are derived for phospholipids, and they help emulsify lipids for a better absorption in the intestine.
True
False
Which of these enzyme helps activate fatty acids?
Carnitine acyltransferase 1
Carnitine acyltransferase 2
Fatty acylCoA Synthetase
AcylCoA acetyltransferase
The rate limiting step of beta oxidation is catalyzed by
AcylCoA dehydrogenase
EnoylCoA hydratase
Fatty AcylCoA synthetase
Carnitine Acyl transferase 1
Beta oxidation can occur in which of these organelles? Select all that apply
Lysosomes
mitochondria
peroxisome
Endoplasmic reticulum
Which of these enzymes is/are involved in beta oxidation in the peroxisome? Select all that apply
Catalase
AcylCoA reductase
AcylCoA oxidase
Fatty acylCoA synthetase
Which is Not a ketone body?
Acetoacetate
Acetone
D-b-hydroxybutyrate
All of these options are ketone bodies
The rate limiting enzymes for ketone bodies synthesis is...
HMG CoA reductase
HMG CoA Synthase
HMG CoA Lyase
Acetoacetate decarboxylase
b-Hydroxybutyrate dehydrogenase
Diabetes can be accompanied by ketoacidosis.
True
False
Find the good matches (select all that apply).
Beta oxidation: cytosol
Fatty acid synthesis: NAD/FAD
Fatty acid synthesis: enzyme-bound SH groups
Fatty acid synthesis: NADPH
The rate limiting step of fatty acid synthesis is catalyzed by
Fatty acid synthase
Acetyl CoA carboxylase
Which of these processes is glycerol kinase involved in?
Fatty acid synthesis
TGA synthesis
TGA catabolism
Glycerophospholipid synthesis
Under low concentrations of sterols in the ER, where is the regulatory region of SREBP located?
ER membrane
Proteasome
Insing
Nucleus
Which enzyme is inhibited by the statins?
HMG CoA synthase
HMG CoA reductase
Thiolase
Mevalonate kinase
