WorksheetsIMHM LEC WEEK 3: BASIC IMMUNOLOGY
Total questions: 73
Worksheet time: 55mins
It is a study of a host's reactions when foreig substances are intriduced into the body
(a)
A foreign substance that induces such an immune response
(a)
Ability of an individual to resist infections by means of normally present body infections; innate
natural immunity
acquired immunity
type of resistance that is characterized by specificity for each individual pathogen, micorbial agent
natural immunity
acquired immunity
this is when your body produces antibodies when you are sick
naturally acquired active immunity
artifically acquired active immunity
it reduces the virulence factor of a certain patogen
(a)
It is ued to treat mycobacterium tuberculosis. it is the wicked version of mycobacterium bovis
(a)
A bacteria that is closely related to mycobacterium tuberculosis
(a)
engulfment of cells and particulate matter by leukocyte, macrophage, and other cells
(a)
These are cells that are attracted to the site of inflammatio by chemical substances
(a)
toward the inflammation by chemical substances
positive chemotaxis
negative chemotaxis
away from the stimulus
positive chemotaxis
negative chemotaxis
These are chemical messengers which is why thre is migration in our cells within the attracted site of inflammation
(a)
coating of antibody and/or complement to facilitate phagocytosis
(a)
it is a greek word that means "be prepared for eating"
(a)
They are serym proteins and they are attached to a foreign substacnes and it helps to prepare for the phagocytosis
(a)
via opsonin receptors that recognize opsonin such as IgG, CRP and C3b bound to microorganisms
indirect phagocytosis
direct phagocytosis
via pattern recognition receptors (PRR) that recognizes lipid and carbohydrate sequences on microorganisms
indirect phagocytosis
direct phagocytosis
It is the overall reaction of the body to injury or invasion by an infection agent
(a)
It is the 1st cell to migrate to the site of inflammation
neutrophil
macrophages
monocytes
NOTA
It is the 2nd cell to migrate to the site of inflammation
neutrophil
macrophages
monocytes
there are 2 correct answers
NOTA
RUBOR
redness
swelling
heat
pain
tumor
redness
swelling
heat
pain
calor
redness
swelling
heat
pain
dolor
heat
pain
loss of function
redness
functio laesa
redness
loss of function
swelling
pain
Function: opsonization & complement activation
c reactive protein
serym amyloid A
alpha antitrypsin
haptoglobin
Function: removal of cholesterol
C reactive protein
serum amyloid A
alpha antitrypsin
fibrinogen
function: protease inhibitor
alpha antitrypsin
fibrinogen
haptoglobin
ceruloplasmin
function: clot formation
alpha antitrypsin
fibrinogen
haptglobin
ceruloplasmin
function: bind hemoglobin
alpha antitrypsin
fibrinogen
haptoglobin
ceruloplasmin
function: binds copper and oxidizes iron
haptoglobin
ceruloplasmin
complement C3
mannose binding protein
function: opsonization and lysis
ceruloplasmin
complement C3
mannose binding protein
function: complement activation
alpha antitrypsin
complement C3
mannose binding protein
ceruloplasmin
It serves as a chemical messenger and it influence the activities of other cells
(a)
it affects the same cell that secreted it
autocrine stimulation
paracrine stimulation
it affects the target cell in close proximity
autoccrine stimulation
paracrine stimulation
It refers to a substance that reacts with antibody or sensitized T cells but may not be able to evoke an immune response in the first place
(a)
synthetic polymers
(a)
they are molecular shapes or configuration tha tare recognized by B or T cells
(a)
These are incomplete antigens that are able to stimulate it into an immune response
(a)
these are those antigens that beongs to the host
autoantigens
alloantigens
These are from other members of the host's species, and these are capable fo eliciting an immune response
autoantigens
alloantigens
It is also knwon as the scene graph tha tis derived from the different class but identical individuals
(a)
These are substance administered with an immunogen that increases the immune response
(a)
These are the only ones approved for clinical use in the united states, and these are used to complex with the imunogen to increase its size and to prevent a rapid escape from the tissues
(a)
MHC meaning
(a)
A french scientist that gav ehis name, because they were first defined by discovering an antibody response to circulating white blood cells
(a)
it plays a role in graph rejection which is why it should be histocompatible
(a)
It serves as watch dog for viral tumor and certain antigens that are synthesized in the cell
class 1
class 2
class 3
they are found primarily in the antigen presenting cells (APC) and it includes the b lymphocytes, monocytes, macrophages and dendritic cells
class 1
class 2
class 3
it can be class 1 or class 2 regions which is located on the chromosome6
class 1
class 2
class 3
he used pepsin to obtain additional evidence for the structure of immunoglobulins
(a)
one signle fragment with a molecule weight of 100,000 and all the antigen binding ability knonw as?
(a)
composed of 2 light chains and 2 halves of heavy chain
1 fab
1 fc
fab region
constant region
Similar to fc except that it is disintegrated into several smaller pieces
1 fab
1fc
fab region
the H chain that is unique to each immunoglobulin
isotype
allotype
idiotype
genetic variation in the constant regions
isotype
allotype
idiotype
variations in variable regions that give individual antibody molecule specificity
isotype
allotype
idiotype
the segment of H chain located between the CH1 and CH2 regions is known as
(a)
mmunoglobulins that has hinge regions
IgG
IgD
IgA
IgE
IgM
immunoglobulins that has no hinge region
IgG
IgD
IgA
IgE
IgM
It is important for the hinge regions because it determines the number of the antigen binding site
(a)
It is the most predominant immunoglobulin
(a)
IgM is also known as?
(a)
It is known as the primary response because it is th efirst to appear when it comes to an antigenic stimulation
(a)
An immunoglobulin that does not cross the placenta
(a)
It is characterized by a long lag phase, slow exponential increase in antibody, and short lived response
primary response
secondary response
It has a shortened lag period, antibody rise is much more rapid, and serum levels remain higher for longer period
primary response
secondary response
It is synthesized in the plasma cells that is found mainly in the mucosal associated lymphoid tissue or the mouth
(a)
It is found as a dimier along the respiratory, urogenital, and intestinal mucosa, and it also appears in milk, saliva, tears, and sweat
(a)
An immunoglobulin that is found on the surface of immunocomponent but unstimulated B lymphocytes abd plays an important role in the B cell activation
(a)
It is the least abundant immunoglobulin in the serum and the most heat labile of all immunoglobulins and does not participate imunoglobulin reactions
(a)
