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AP Unit 4: Test Review

Total questions: 60

Worksheet time: 50mins

Name
Class
Date
1.
A signal molecule that binds to a plasma-membrane protein is a
a)
ligand
b)
second messenger
c)
protein kinase
d)
receptor protein
2.

What type of signaling is shown here?

a)

autocrine

b)

synaptic

c)

endocrine

d)

paracrine

3.

Long distance signals involving hormones are ________ signals.

a)

paracrine

b)

synaptic

c)

endocrine

4.

An example of LOCAL cell communication is:

a)

White blood cells bumping into each other sharing antigen info

b)

Neurons communicating across a synapse

c)

Hormones traveling through the blood stream to target tissues

5.

Which of the following is a chemical message that usually travels through the bloodstream to target cells?

a)

hormone

b)

local regulator

c)

endocrine cell

d)

plasmodesmata

6.

Choose the correct order of communication.

a)

reception, response, transduction

b)

transduction, reception, response

c)

response, transduction, reception

d)

reception, transduction, response

7.

What does protein phosphatase do?

a)

Removes phosphates to shut off pathways through dephosphorylation.

b)

Adds phosphates from ATP to proteins to relay signals.

8.
Which of the following can activate a protein by transferring a phosphate group to it?
a)
cAMP
b)
protein kinase
c)
protein phosphatase
9.

A cell converting a chemical signal into a cellular response is known as __.

a)

reception

b)

transduction

c)

response

10.

What do secondary messengers, like cAMP, do?

a)

transport a signal through the lipid bilayer

b)

relay & amplify a message from the inside of the membrane throughout the cytoplasm

c)

reduce the signal of a ligand

11.

What type of transmembrane receptor is being shown?

a)

Ligand Gated Ion Channel

b)

G-protein Coupled Receptor

12.

A protein called Sonic Hedgehog plays a key role in vertebrate embryonic development. When this protein is released by secretory cells, it travels through the extracellular fluid and signals adjacent cells to go through the process of cell differentiation (process of cells becoming specialized). Sonic hedgehog is thought to be especially important for the development of the brain and limbs. What type of signaling is this an example of?

a)

Synaptic Signaling (Local)

b)

Paracrine Signaling (Local)

c)

Endocrine Signaling (Long Distance)

13.

Adjacent plant cells have narrow channels called plasmodesmata that pass through the cell walls of the connected cells and allow a cytoplasmic connection between the cells.

Which of the following statements best describes a primary function of plasmodesmata?

a)

They allow the movement of molecules from one cell to another, enabling communication between cells.

b)

They prevent the cell membrane from pulling away from the cell wall during periods of drought.

c)

They increase the surface area available for attachment of ribosomes and thus increase protein synthesis.

14.

Which of the following represents a signaling molecule that is used in long-distance signaling?

a)

hormone

b)

second messengers

c)

neurotransmitter

15.

Steroid hormones (non-polar/hydrophobic molecules) can passively diffuse across membranes,

a)

True

b)

False

16.

What is it called when energy is added to a molecule via the addition of a phosphate group?

a)

phosphorylation

b)

dephosphorlation

17.

Largest category of cell surface receptors important to animal sensory systems.

a)

G Protein Coupled Receptors

b)

Ligand Gated Ion Channels

18.

Receptors located in the plasma membrane that are important to the nervous system.

a)

G Protein Coupled Receptors

b)

Ligand Gated Ion Channels

19.

Phosphorylation cascades are often used for

a)

reception

b)

responses

c)

amplification

d)

termination

20.

If ATP were unavailable, what would be the effect on this pathway?

a)

Protein kinase A would not be produced

b)

GDP would not bind to the transmembrane protein

c)

The hormone would not bind to the transmembrane protein

d)

The secondary messenger would not be produced

21.

Classify the image by their type of communication.

a)

Direct Contact (Animal Cell)

b)

Direct Contact (Plant Cell)

c)

Long Distance / Endocrine Signaling

d)

Local Signaling / Paracrine

e)

Local Signaling / Synaptic Signaling

22.

Classify the image by their type of communication.

a)

Direct Contact (Animal Cell)

b)

Direct Contact (Plant Cell)

c)

Long Distance / Endocrine Signaling

d)

Local Signaling / Paracrine

e)

Local Signaling / Synaptic Signaling

23.

What is direct contact communication in animal cells called?

a)

Gap Junctions

b)

Plasmodesmata

24.

What is the stage of signal transduction labeled A?

a)

Transduction

b)

Response

c)

Reception

d)

Endocrine

25.

How do bacteria sense local population density?

a)

quorum sensing

b)

bacteria sensing

c)

signal sensing

d)

population sensing

26.
What does a protein phosphatase do?
a)
removes phosphates
b)
transfers phosphates from ATP to proteins
c)
activates an enzyme with a signal molecule
27.

When a blood vessel is damaged, platelets will rush to the site of damage and adhere to the vessel beginning the formation of a blood clot. These platelets will then release a chemical into the bloodstream, which recruits even more platelets to rush to the site of damage. As more platelets accumulate, more of the signaling chemical is released into the blood. This process will end when the blood has been sufficiently clotted and active bleeding is no longer occurring. What type of feedback loop is blood clotting an example of?

a)

Negative Feedback Loop

b)

Positive Feedback Loop

28.

When we are dehydrated, ADH is released which causes more water to be absorbed into our bloodstream. What type of feedback does this represent?

a)

Positive feedback

b)

Negative feedback

29.

How is negative feedback different from positive feedback?

a)

Negative feedback harms the body

b)

Negative feedback works to reverse a change in a system

c)

Negative feedback is rarer than positive

d)

Negative feedback is slower than positive feedback

30.

A process in which an initial change will bring about more change in the same direction.

a)

negative feedback

b)

positive feedback

31.

Which of the following is NOT an example of a negative feedback loop?

a)

body maintaining a temperature of about 37°C

b)

a ripe apple releasing ethylene, which causes more ripening

c)

heart rate increasing when exercising to deliver more O2 to cells

32.

Which type of feedback loop would mammals use to maintain a constant body temperature?

a)

Postive

b)

Negative

33.
What type of feedback loop is shown?
a)
negative
b)
neutral 
c)
positive
34.
Why do cells go through cell division
a)
Growth
b)
Reproduction
c)
Repair
d)
All of the above
35.
Structure (b) is a ____.
a)
chromosome
b)
chromatid
c)
centromere
36.
Structure (c) is a ____.
a)
chromosome
b)
chromatid
c)
centromere
37.

Mitosis results in...

a)

2 identical diploid cells

b)

4 unique diploid cells

c)

2 unique haploid cells

d)

4 identical haploid cells

38.

Which phase of the cell cycle is characterized by DNA replication?

a)

G1

b)

S

c)

G2

d)

M Phase

39.
Which of the following shows the correct sequence of the cell cycle?
a)
Mitosis-> G1->S->G2->cytokinesis
b)
S->G1-> G2-> mitosis-> cytokinesis
c)
cytokinesis->mitosis->G1->S->G2
d)
 G1->S->G2->mitosis->cytokinesis
40.

The amount of DNA in a cell is measured right after mitosis and found to be 8 picograms. How many picograms of DNA would be found in a nucleus in the G2 phase?

a)

4

b)

8

c)

16

d)

24

41.

Name the phase:

a)

prophase

b)

anaphase

c)

metaphase

d)

telophase

e)

interphase

42.
Name the phase:
a)
Prophase
b)
Metaphase
c)
Anaphase
d)
Telophase
43.

Which of the following best describes anaphase?

a)

Chromatin condenses into chromosomes, and the nuclear membrane is broken down

b)

Sister chromatids are separated and kinetochores begin pulling chromosomes to opposite poles

c)

Spindle fibers attach to centromeres and begin moving sister chromatids towards the cell's equator

d)

Chromosomes decondense and two nuclei form within the cell

44.
In which phase of mitosis does the nucleus disappear, centrioles move to the poles, and chromosomes condense into sister chromatids?
a)
Prophase
b)
Metaphase
c)
Anaphase
d)
Telophase
45.

Which sequence puts the images in the correct order of the cell cycle?

a)
C,D, B, A, F, E
b)
D,A,F,C,E,B
c)
B,E,C,F,A,D
d)
C,B,D,A E,F
46.

If a cell has 20 chromosomes and under goes mitosis twelve times how many chromosomes will the daughter cell have?I

a)

20

b)

40

c)

240

d)

10

47.

When a plant cell goes undergoes cytokinesis,  _____________.

a)

a cleavage furrow is formed

b)

a cell plate is formed

c)

a contractile ring is formed

48.

Which of the following helps to regulate the cell cycle?

a)

Internal regulators only

b)

External regulators only

c)

Both internal and external regulators

49.

What is the role of cyclins in the cell cycle regulation?

a)

Cyclins regulate the process of apoptosis in the cell cycle.

b)

Cyclins inhibit cyclin-dependent kinases (CDKs) at specific points in the cell cycle.

c)

Cyclins have no role in the cell cycle regulation.

d)

Cyclins activate cyclin-dependent kinases (CDKs) at specific points in the cell cycle.

50.
How does the concentration of cyclin change as a cell goes through the cell cycle?
a)
Cyclin concentration remains constant.
b)
Cyclin concentration increases during interphase and decreases during mitosis.
c)
Cyclin concentration decreases during interphase and increases during mitosis.
d)
Cyclin concentration is inversely related to MPF concentrations.
51.
How does the concentration of cyclin dependent kinases (Cdk) change as the cell proceeds through the cell cycle?
a)
Cdk concentration remains constant.
b)
Cdk concentration increases during interphase and decreases during mitosis.
c)
Cdk concentration decreases during interphase and increases during mitosis.
d)
Cdk concentration correlates directly with MPF concentration.
52.

What is the significance of apoptosis in the cell cycle?

a)

It helps in removing unwanted or damaged cells from the cell cycle.

b)

It helps in repairing damaged DNA in the cell cycle

c)

It causes the cell to divide rapidly

d)

It has no significance in the cell cycle

53.

Which of the following is the stage where the cell no longer divides?

a)

G0

b)

G1

c)

G2

d)

S

54.

Which cell cycle checkpoint is the MOST IMPORTANT that verifies cell size and checks the DNA for damage?

a)

G1 checkpoint

b)

S checkpoint

c)

G2 checkpoint

d)

M checkpoint

55.

Which cell cycle checkpoint makes sure that chromosomes are duplicated and checks for damage of the replicated DNA?

a)

G1 checkpoint

b)

S checkpoint

c)

G2 checkpoint

d)

M checkpoint

56.

Which cell cycle checkpoint makes sure that the chromatids are correctly attached to the spindle fibers?

a)

G1 checkpoint

b)

S checkpoint

c)

G2 checkpoint

d)

M checkpoint

57.

What is the purpose of density-dependent inhibition?

a)

To stop cell division when there is no room

b)

To stimulate cell growth during injury

c)

To ensure DNA replication occurs without problems

d)

To separate sister chromatids during mitosis

58.

Mutations in genes that regulate the cell cycle will most likely lead to what disease?

a)

Cancer

b)

Apoptosis

c)

Meiosis

d)

Diabetes

59.

Which of the following is a true statement?

a)

Benign tumors have cells that have broken away from the main tumor.

b)

Malignant tumors have cells that have broken away from the main tumor.

c)

Malignant tumors consist of cells that have stayed together.

d)

Benign tumors spread through the blood and lymph to other organs

60.

What can be a risk factor for cells to become cancerous?

a)

Genetic factors

b)

Exposure to toxins

c)

Excessive UV light exposure

d)

All of the above