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DNA Replication & Gene expression

Total questions: 61

Worksheet time: 1hrs 2mins

Name
Class
Date
1.
Which of the following best describes a DNA molecule?
a)
double helix
b)
contains ribose
c)
made of amino acids
d)
contains Uracil
2.
Which of the following units are repeatedly joined together to form a strand of DNA? (This is the MONOMER of DNA.) 
a)
amino acids
b)
nucleotides
c)
fatty acids
d)
polysaccharides
3.
Adenine bonds with ______________.
a)
Guanine
b)
Thymine
c)
Cytosine
d)
Adenine
4.
Guanine bonds with ______________.
a)
Adenine
b)
Guanine
c)
Cytosine
d)
Thymine
5.
Why is DNA important?
a)
it is very small and very complicated
b)
it's in everything
c)
it serves as the blueprint for traits of all living things
d)
because we eat it every day for energy
6.
What are the 4 nitrogen bases?
a)
adenine, thymine, cytoplasm, and guanine
b)
adenine, thymine cytosine, and guanine
c)
adenine, thymine, cytosine, and gylcerol
d)
adenine, thymine, cytosine, and glucose
7.
Which 2 molecules forms the sides (backbone) of the DNA ladder?
a)
deoxyribose and adenine
b)
deoxyribose and a hydrogen bond
c)
sugar and the nucleus
d)
deoxyribose (sugar) and phosphate
8.
Which enzyme is responsible for adding nucleotides?
a)
Topoisomerase
b)
DNA Polymerase
c)
Ligase
d)
Primase
9.
Which sequence of DNA bases would pair with this partial strand
ATG TGA CAG
a)
ATG TGA CAG
b)
TAC ACT GTC
c)
GTA AGT GAC
d)
CAT TCA CTG
10.
A process in which DNA has the unique ability to make an exact copy of itself.
a)
Replication
b)
Translation
c)
Transcription
11.
Nitrogenous bases are joined by which type of bond?
a)
polar bonds
b)
ionic bonds
c)
covalent bonds
d)
hydrogen bonds
12.

Which enzyme is responsible for unzipping or the DNA molecule when replication begins?

a)

Helicase

b)

DNA breakase

c)

Primase

d)

DNA polymerase

13.

Where does the DNA molecule unzip at during DNA replication?

a)

Between the sugar and phosphate

b)

Between the sugar and nitrogen bases

c)

Between the nitrogen bases

14.

Which part of a DNA molecule is responsible for the direct coding of specific traits in an organism?

a)

The number of hydrogen bonds that hold the strands of DNA together

b)

The number of carbons in the DNA molecule.

c)

The sequence of nucleotide bases in the DNA molecule

d)

The sequences of phosphates along each DNA strand

15.
DNA replication results in two DNA molecules,
a)
each one with two original strands
b)
each one with two new strands
c)
each one with one new strand and one original strand
d)
one with two new strands and the other with two original strands
16.
order of replication
a)
3, 2, 1, 4
b)
2, 1, 4, 3
c)
2, 3, 1, 4
d)
3, 4, 1, 2
17.
What are the three components of a nucleotide?
a)
sugar, hydrogen, nitrogen base
b)
sugar, oxygen, nitrogen base
c)
sugar, phosphate, nitrogen base
d)
sugar, phosphate, protein
18.

Compliment the following strand of DNA:  AATCATGGA

a)

AATCATGGA

b)

TTAGTACCT

c)

UUAGUACCU

d)

GGATAUCUA

19.
What determines the code, or information, of a DNA molecule?
a)
the shape (structure) of the nitrogen bases
b)
the order (sequence) of the nitrogen bases
c)
the color of the nitrogen bases
d)
the frequency (number) of nitrogen bases
20.
In a molecule of double-stranded DNA, the amount of Adenine present is always equal to the amount of
a)
cytosine
b)
guanine
c)
thymine
d)
uracil
21.
What sugar is in DNA?
a)
deoxyribose
b)
ribose
c)
oxyribose
d)
deoxyose
22.
Which organelle is DNA usually found in?
a)
cell membrane
b)
vacuole
c)
chloroplast
d)
nucleus
23.

a)

A

b)

B

c)

C

d)

D

24.

a)

A

b)

B

c)

C

d)

D

25.

a)

A

b)

B

c)

C

d)

D

26.

a)

F

b)

G

c)

H

d)

J

27.

a)

A

b)

B

c)

C

d)

D

28.

Enzyme that connects the DNA to the backbone (glues)

a)

Ligase

b)

Polymerase

c)

Helicase

d)

Primase

29.

#1 in the picture above (builder)

a)

Helicase

b)

Primase

c)

Polymerase

d)

Ligase

30.
Which of the following is a base that is NOT contained in DNA?
a)
Adenine
b)
Thymine
c)
Uracil
d)
Guanine
31.
What sugar is in DNA?
a)
deoxyribose
b)
ribose
c)
oxyribose
d)
deoxyose
32.
What is the purpose of DNA Replication?
a)
ensures that every cell has exactly half of the DNA as original
b)
assures that every cell has a complete set of identical genetic information
c)
ensures each cell has twice as much DNA as the original
d)
ensures that your offspring will look just like you
33.

Nitrogen bases pair in a specific way. What is this called?

a)

complementary

b)

antiparallel

c)

hydrogen bonding

d)

homologous

34.

Match with the complementary strand.


TACCGTAGCCG

a)

ATGGCGTCGGC

b)

TTGGCATCGGC

c)

ATGGCATCGGC

d)

ATGGCATGGGC

35.

What enzyme reads the original DNA and match complementary nucleotides to build a new DNA strand

a)

Helicase

b)

DNA polymerase

c)

Ligase

d)

primase

36.

Where in the cell does DNA replication take place?

a)

mitochondria

b)

cytoplasm

c)

nucleus

d)

ribosome

37.

A piece of DNA that has instructions to code for one protein is called _______________?

a)

chromosome

b)

gene

c)

primase

d)

codon

38.

What type of bond is between the nitrogen bases?

a)

covalent

b)

hydrogen

c)

phosphodiester

d)

carbon

39.
Which sugar is contained in DNA
a)
Dextrose
b)
Ribose
c)
Deoxyribose
d)
Glucose
40.
Given the following sequence - ATGCGTGACGATA
The complimentary sequence would be...
a)
ATGCGTGACGATA
b)
UACGCACUGCUAU
c)
TACGCACTGCTAT
d)
TACGTCGATATGE
41.

Which of the following describes the difference between a purine and a pyrimidine?

a)

Purines are single ring structures while pyrimidines are double ring structures.

b)

Pyrimidines are single ring structures while purines are double ring structures.

c)

Purines are composed of single bonds while pyrimidines are composed of double bonds.

d)

Pyrimidines are composed of single bonds while purines are composed of double bonds.

42.

Which of the following are purines?

a)

adenine

b)

cytosine

c)

guanine

d)

thymine

43.

Which of the following are pyrimidines?

a)

adenine

b)

cytosine

c)

guanine

d)

thymine

44.

The picture below shows an enzyme unwinding and unzipping DNA.

​

​What is the name of this enzyme?

a)

DNA Helicase

b)

DNA Ligase

c)

DNA polyermase

d)

RNA Polymerase

45.

Which of the following DNA nucleotides are paired with the correct corresponding DNA nucleotide? (mark all that apply)

a)

Adenine with Thymine

b)

Guanine with Cytosine

c)

Thymine with Cytosine

d)

Adenine with Uracil.

e)

Uracil with Thymine

46.
The following picture must be
a)
DNA because it's double stranded
b)
RNA because it's single stranded
c)
DNA because it's single stranded
d)
RNA because it's double stranded
47.
The sugar in RNA is ____________________.
a)
deoxyribose
b)
ribose
48.
DNA contains the bases Adenine, Guanine, Cytosine and Thymine.  Which base is replaced in RNA by another base?
a)
Adenine is replaced by Uracil
b)
Thymine is replaced by Uracil
c)
Guanine is replaced by Uracil
d)
Cytosine is replaced  Uracil
49.
In RNA, adenine goes with __________.
a)
adnine
b)
cytosine
c)
thymine
d)
uracil
50.
How would the DNA sequence GCTATA be transcribed to mRNA?
a)
GCUAUA
b)
CGATAT
c)
CGAUAU
d)
GCUTUT
51.

Transcribe the following DNA sequence into RNA: (Hint! Remember that RNA has U instead of T!)


AAT TAG GGC TCG

a)

AAT TAG GGC TCG

b)

TTA ATC CCG AGC

c)

UUA AUC CCG AGC

d)

TTU UTC CCG UGC

52.

What is Transcription?

a)

The making DNA segment.from mRNA.

b)

The making of an RNA strand into a protein.

c)

The making of an mRNA strand from the DNA template.

53.
Amino acids are the building blocks of... 
a)
DNA
b)
RNA
c)
Atoms
d)
Proteins
54.

Which of the following is correct?

a)

Nucleotide triplets (a codon) code a single amino acid.

b)

Each amino acid codes a nucleotide.

c)

Each nucleotide codes an amino acid.

d)

Amino acid triplets code a single nucleotide.

55.
_______ is made during transcription and ________ is made during translation.
a)
mRNA / a protein
b)
a protein / mRNA
c)
Ribosome / Nucleus
d)
mRNA / tRNA
56.
What amino acid is represented by the codon CAG?
a)
Aspartic Acid
b)
Histidine
c)
Glutamine
d)
Methionine
57.

Where does TRANSCRIPTION occur?

a)

Nucleus

b)

Ribosome

c)

Cytoplasm

d)

Mitochondria

58.

TRANSLATE this RNA sequence: AUGCAAUGA

a)

Met-Glu-Stop

b)

Met-His-Stop

c)

Thr-Glu-Stop

d)

Thr-Pro-Stop

59.
The DNA sequence ATCAGCGCTGGC is part of a gene. how many amino acids are coded for by this message?
a)
4
b)
8
c)
12
d)
20
60.
Choose the nucleotide sequence of the RNA strand that would be complementary to the following strand: 
GTAGTCA
a)
UATUAGA
b)
ACGACTG
c)
CAUCAGU
d)
CATCAGT
61.
What is the correct amino acid sequence for the mRNA code AUGCCAGUAUGA
a)
Met-Pro-Ala-Val
b)
Met-Pro-Val
c)
Tyr-Gly-His
d)
Tyr-Gly-Arg-His

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